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Published in: Journal of Neurology 12/2006

01-12-2006 | REVIEW

News on the genetics, epidemiology, medical care and translational research of Schwannomas

Authors: C.O. Hanemann, D.G. Evans

Published in: Journal of Neurology | Issue 12/2006

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Abstract

Recent years have seen substantial news and updates in the genetics and diagnosis of schwannomas, even a new hereditary disease with schwannomas; Schwannomatosis has been defined. These developments have consequently led to better evaluation of the incidence of schwannomas. Although there has also been progress in the treatment of schwannomas especially in the field of radiation therapy, hereditary diseases with multiple tumours still represent a therapeutic dilemma. NF2 in particular still causes major morbidity and mortality owing to the neurological deficit of multiple tumour disease and deafness caused by vestibular nerve involvement. Thus there has been great enthusiasm about disease models in the hope that translational research will give rise to new therapies.
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Metadata
Title
News on the genetics, epidemiology, medical care and translational research of Schwannomas
Authors
C.O. Hanemann
D.G. Evans
Publication date
01-12-2006
Publisher
Steinkopff-Verlag
Published in
Journal of Neurology / Issue 12/2006
Print ISSN: 0340-5354
Electronic ISSN: 1432-1459
DOI
https://doi.org/10.1007/s00415-006-0347-0

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