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01-05-2017 | Population Data

Study of InDel genetic markers with forensic and ancestry informative interest in PALOP’s immigrant populations in Lisboa

Authors: Ana Inácio, Heloísa Afonso Costa, Cláudia Vieira da Silva, Teresa Ribeiro, Maria João Porto, Jorge Costa Santos, Gilberto Igrejas, António Amorim

Published in: International Journal of Legal Medicine | Issue 3/2017

Abstract

The migratory phenomenon in Portugal has become one of the main factors for the genetic variability. In the last few years, a new class of autosomal insertion/deletion markers—InDel—has attracted interest in forensic genetics. Since there is no data for InDel markers of Portuguese-speaking African countries (PALOP) immigrants living in Lisboa, our aim is the characterization of those groups of individuals by typing them with at least 30 InDel markers and to compare different groups of individuals/populations. We studied 454 bloodstain samples belonging to immigrant individuals from Angola, Guinea-Bissau, and Mozambique. DNA extraction was performed with the Chelex® 100 method. After extraction, all samples were typed with the Investigator® DIPplex method. Through the obtained results, allelic frequencies show that all markers are at Hardy-Weinberg equilibrium, and we can confirm that those populations show significant genetic distances between themselves, between them, and the host Lisboa population. Because of this, they introduce genetic variability in Lisboa population.

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Title: Study of InDel genetic markers with forensic and ancestry informative interest in PALOP’s immigrant populations in Lisboa
Authors: Ana Inácio
Heloísa Afonso Costa
Cláudia Vieira da Silva
Teresa Ribeiro
Maria João Porto
Jorge Costa Santos
Gilberto Igrejas
António Amorim
Publication date: 01-05-2017
Publisher: Springer Berlin Heidelberg
Published in: International Journal of Legal Medicine / Issue 3/2017
Print ISSN: 0937-9827
Electronic ISSN: 1437-1596
DOI: https://doi.org/10.1007/s00414-016-1484-3

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Study of InDel genetic markers with forensic and ancestry informative interest in PALOP’s immigrant populations in Lisboa

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