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01-01-2012 | Technical Note

Method to predict the chance of developing a male profile out of mixtures of male and female DNA

Authors: Patrick Johannes Laberke, Rahel Grossenbacher, Roland Hausmann, Beate Balitzki

Published in: International Journal of Legal Medicine | Issue 1/2012

Abstract

In forensic examination it is a standard to take vaginal swabs from victims of sexual assault for further molecular genetic analysis. Laboratories then are usually confronted with mixtures of lots of female and only a small amount of male DNA. Nowadays it is possible to work with specific Y chromosomal markers after DNA extraction by differential lysis. The determined ratio of autosomal DNA and Y chromosomal DNA can be used to identify the possibility of generating a male profile in these samples.

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Title: Method to predict the chance of developing a male profile out of mixtures of male and female DNA
Authors: Patrick Johannes Laberke
Rahel Grossenbacher
Roland Hausmann
Beate Balitzki
Publication date: 01-01-2012
Publisher: Springer-Verlag
Published in: International Journal of Legal Medicine / Issue 1/2012
Print ISSN: 0937-9827
Electronic ISSN: 1437-1596
DOI: https://doi.org/10.1007/s00414-011-0615-0

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Springer Medicine

Method to predict the chance of developing a male profile out of mixtures of male and female DNA

Abstract

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Abstract

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