Top

Published in:

01-05-2009 | Short Communication

Meiosis study in a population sample from Nigeria: allele frequencies and mutation rates of 16 STR loci

Authors: Carsten Hohoff, Marianne Schürenkamp, Bernd Brinkmann

Published in: International Journal of Legal Medicine | Issue 3/2009

Abstract

Allele frequencies for the 16 short tandem repeat (STR) loci D2S1338, D3S1358, D5S818, D7S820, D8S1179, D13S317, D16S539, D18S51, D19S433, D21S11, ACTBP2, CSF1PO, FGA, TH01, TPOX and VWA were determined for 337 immigrants from Nigeria. All loci were in Hardy–Weinberg equilibrium. More than 6,000 meiotic transfers were investigated and ten mutations were observed. Single mutations were observed in the STR systems D2S1338, D3S1358, D7S820, D8S1179, D16S539 and FGA, whereas two mutations were observed in the systems D21S11 and VWA.

Available only for authorised users

Heinrich M, Müller M, Rand S, Brinkmann B, Hohoff C (2004) Allelic drop-out in the STR system ACTBP2 (SE33) as a result of mutations in the primer binding region. Int J Legal Med 118:361–363PubMedCrossRef

Hohoff C, Schürenkamp M, Börchers T, Eppink M, Brinkmann B (2006) Meiosis study in a population sample from Afghanistan: allele frequencies and mutation rates of 16 STR loci. Int J Legal Med 120:300–302PubMedCrossRef

Heinrich M, Felske-Zech H, Brinkmann B, Hohoff C (2005) Characterisation of variant alleles in the STR systems D2S1338, D3S1358 and D19S433. Int J Legal Med 119:310–313PubMedCrossRef

Brinkmann B, Klintschar M, Neuhuber F, Hühne J, Rolf B (1998) Mutation rate in human microsatellites: influence of the structure and length of the tandem repeat. Am J Hum Genet 62:1408–1415PubMedCrossRef

Griffiths RAL, Barber MD, Johnson PE et al (1998) New reference allelic ladders to improve allelic designation in a multiplex STR system. Int J Legal Med 111:267–272PubMedCrossRef

Gusmao L, Butler JM, Carracedo A et al (2006) DNA Commission of the International Society of Forensic Genetics (ISFG): an update of the recommendations on the use of Y-STRs in forensic analysis. Int J Legal Med 120:191–200PubMedCrossRef

Title: Meiosis study in a population sample from Nigeria: allele frequencies and mutation rates of 16 STR loci
Authors: Carsten Hohoff
Marianne Schürenkamp
Bernd Brinkmann
Publication date: 01-05-2009
Publisher: Springer-Verlag
Published in: International Journal of Legal Medicine / Issue 3/2009
Print ISSN: 0937-9827
Electronic ISSN: 1437-1596
DOI: https://doi.org/10.1007/s00414-008-0307-6

At a glance: The ONWARDS insulin icodec trials

Springer Medicine

Meiosis study in a population sample from Nigeria: allele frequencies and mutation rates of 16 STR loci

Abstract

At a glance: The ONWARDS insulin icodec trials

Springer Medicine

Abstract

Please log in to get access to this content

Other articles of this Issue 3/2009

Evaluation of the ossification of the medial clavicular epiphysis with a digital ultrasonic system to determine the age threshold of 21 years

Virtopsy—noninvasive detection of occult bone lesions in postmortem MRI: additional information for traffic accident reconstruction

Thirteen X-chromosomal short tandem repeat loci multiplex data from Taiwanese

Time-dependent appearance of intrathrombus neutrophils and macrophages in a stasis-induced deep vein thrombosis model and its application to thrombus age determination

Variants of the melanocortin 1 receptor gene (MC1R) and P gene as indicators of the population origin of an individual

Chemical submission: results of 4-year French inquiry