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01-05-2008 | Short Communication

Analysis of Y-chromosomal SNP haplogroups and STR haplotypes in an Algerian population sample

Authors: C. Robino, F. Crobu, C. Di Gaetano, A. Bekada, S. Benhamamouch, N. Cerutti, A. Piazza, S. Inturri, C. Torre

Published in: International Journal of Legal Medicine | Issue 3/2008

Abstract

The distribution of Y-chromosomal single nucleotide polymorphism (SNP) haplogroups and short tandem repeat (STR) haplotypes was determined in a sample of 102 unrelated men of Arab origin from northwestern Algeria (Oran area). A total of nine different haplogroups were identified by a panel of 22 binary markers. The most common haplogroups observed in the Algerian population were E3b2 (45.1%) and J1 (22.5%). Y-STR typing by a 17-loci multiplex system allowed 93 haplotypes to be defined (88 were unique). Striking differences in the allele distribution and gene diversity of Y-STR markers between haplogroups could be found. In particular, intermediate alleles at locus DYS458 specifically characterized the haplotypes of individuals carrying haplogroup J1. All the intermediate alleles shared a common repeat sequence structure, supporting the hypothesis that the variant originated from a single mutational event.

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Title: Analysis of Y-chromosomal SNP haplogroups and STR haplotypes in an Algerian population sample
Authors: C. Robino
F. Crobu
C. Di Gaetano
A. Bekada
S. Benhamamouch
N. Cerutti
A. Piazza
S. Inturri
C. Torre
Publication date: 01-05-2008
Publisher: Springer-Verlag
Published in: International Journal of Legal Medicine / Issue 3/2008
Print ISSN: 0937-9827
Electronic ISSN: 1437-1596
DOI: https://doi.org/10.1007/s00414-007-0203-5

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