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European Archives of Psychiatry and Clinical Neuroscience

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01-02-2014 | Short Communication

Evaluation of autonomic nervous system by salivary alpha-amylase level and heart rate variability in patients with schizophrenia

Authors: Masa Ieda, Tsuyoshi Miyaoka, Rei Wake, Kristian Liaury, Keiko Tsuchie, Michiyo Fukushima, Tomoko Araki, Satoko Ezoe, Takuji Inagaki, Jun Horiguchi

Published in: European Archives of Psychiatry and Clinical Neuroscience | Issue 1/2014

Abstract

Several researches indicate that autonomic nervous system (ANS) dysfunction in patients with schizophrenia. Recently, salivary alpha-amylase (sAA) has been employed as a useful marker for ANS function. We investigated the extent of ANS dysfunction by measuring sAA and heart rate variability (HRV) of 25 patients with schizophrenia compared with controls. Schizophrenia group demonstrated a significant increase in sAA and markedly lower parasympathetic nervous system (PNS) activity in the HRV. However, there were no significant differences between two groups in sympathetic nervous system (SNS) activity. We concluded that PNS might be suppressed and the SNS shows relatively high activity in schizophrenia.

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Title: Evaluation of autonomic nervous system by salivary alpha-amylase level and heart rate variability in patients with schizophrenia
Authors: Masa Ieda
Tsuyoshi Miyaoka
Rei Wake
Kristian Liaury
Keiko Tsuchie
Michiyo Fukushima
Tomoko Araki
Satoko Ezoe
Takuji Inagaki
Jun Horiguchi
Publication date: 01-02-2014
Publisher: Springer Berlin Heidelberg
Published in: European Archives of Psychiatry and Clinical Neuroscience / Issue 1/2014
Print ISSN: 0940-1334
Electronic ISSN: 1433-8491
DOI: https://doi.org/10.1007/s00406-013-0411-6

At a glance: The STEP trials

Springer Medicine

Evaluation of autonomic nervous system by salivary alpha-amylase level and heart rate variability in patients with schizophrenia

Abstract

At a glance: The STEP trials

Springer Medicine

Abstract

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