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European Archives of Psychiatry and Clinical Neuroscience

Published in:

01-11-2008

Neurochemical dementia diagnostics: assays in CSF and blood

Authors: Piotr Lewczuk, Joachim Hornegger, Rüdiger Zimmermann, Markus Otto, Jens Wiltfang, Johannes Kornhuber

Published in: European Archives of Psychiatry and Clinical Neuroscience | Special Issue 5/2008

Abstract

In this review, current neurochemical dementia diagnostics (NDD) procedures are presented with a focus on biomarkers in the cerebrospinal fluid (CSF) and blood: amyloid β peptides, tau protein, and its phosphorylated form (pTau). CSF analysis is an increasingly important tool for early and differential diagnosis of dementia syndromes. Although lumbar puncture is a mildly invasive procedure with a low incidence of complications, establishing blood assays capable of reliably measuring NDD biomarkers is an aim of several studies worldwide.

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Title: Neurochemical dementia diagnostics: assays in CSF and blood
Authors: Piotr Lewczuk
Joachim Hornegger
Rüdiger Zimmermann
Markus Otto
Jens Wiltfang
Johannes Kornhuber
Publication date: 01-11-2008
Publisher: D. Steinkopff-Verlag
Published in: European Archives of Psychiatry and Clinical Neuroscience / Issue Special Issue 5/2008
Print ISSN: 0940-1334
Electronic ISSN: 1433-8491
DOI: https://doi.org/10.1007/s00406-008-5005-3

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Neurochemical dementia diagnostics: assays in CSF and blood

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