Skip to main content
Top
Published in: European Archives of Oto-Rhino-Laryngology 12/2021

01-12-2021 | Endoscopy | Laryngology

An epidemiological survey of gastroesophageal reflux disease at the digestive endoscopy center in Guangzhou

Published in: European Archives of Oto-Rhino-Laryngology | Issue 12/2021

Login to get access

Abstract

Objective

This study aims to investigate the detection rates, common symptoms and risk factors of gastroesophageal reflux disease (GERD), and laryngopharyngeal reflux disease (LPRD) at the digestive endoscopy center.

Methods

A multicenter cross-sectional survey conducted at three hospitals and a total of 565 eligible participants were enrolled. All the patients completed routine ENT examination, gastroscopy, gastroesophageal reflux questionnaire (GerdQ), reflux symptom index (RSI) and a self-designed 25-item symptoms table survey.

Results

Among the 565 eligible participants, the detection rates of GERD and LPRD were 18.41% (104/565) and 9.91% (56/565), respectively. The detection rate of GERD combined with LPRD was 3.19% (18/565). Among GERD and LPRD patients, males (vs. females), middle-aged and elderly patients (vs. young people), BMI ≥ 24.0 kg/m2 (vs. BMI < 24.0 kg/m2), with current smoking history (vs. no smoking), and current drinking history (vs. no drinking), lying down immediately after meal (vs. no lying down immediately after meal) were significantly higher (all p < 0.05). The most common extraesophageal symptoms in patients with GERD were dry mouth (66.35%), globus sensation (56.73%), dry throat and pharyngeal itching (55.77%). The most common extraesophageal symptoms in patients with LPRD were globus sensation (91.07%), dry throat and pharyngeal itching (83.93%), and dry mouth (82.14%).

Conclusion

GERD and LPRD had a high detection rate at the digestive endoscopy center in Guangzhou, China. Older age, BMI ≥ 24.0 kg/m2, smoking and drinking history were risk factors for both GERD and LPRD. Neither GerdQ nor RSI scores included common extraesophageal symptoms.
Literature
16.
go back to reference Sataloff RT, Hawkshaw MJ, Gupta R (2010) Laryngopharyngeal reflux and voice disorders: an overview on disease mechanisms, treatments, and research advances. Discov Med 10(52):213–224PubMed Sataloff RT, Hawkshaw MJ, Gupta R (2010) Laryngopharyngeal reflux and voice disorders: an overview on disease mechanisms, treatments, and research advances. Discov Med 10(52):213–224PubMed
17.
go back to reference GBD 2017 Gastro-oesophageal Reflux Disease Collaborators (2020) The global, regional, and national burden of gastro-oesophageal reflux disease in 195 countries and territories, 1990–2017: a systematic analysis for the Global burden of disease study 2017. Lancet Gastroenterol Hepatol 5(6):561–581. https://doi.org/10.1016/S2468-1253(19)30408-XCrossRef GBD 2017 Gastro-oesophageal Reflux Disease Collaborators (2020) The global, regional, and national burden of gastro-oesophageal reflux disease in 195 countries and territories, 1990–2017: a systematic analysis for the Global burden of disease study 2017. Lancet Gastroenterol Hepatol 5(6):561–581. https://​doi.​org/​10.​1016/​S2468-1253(19)30408-XCrossRef
21.
22.
go back to reference Ryan B, Karl-Hermann F, Wolfram B et al (2020) Clinical presentation of gastroesophageal reflux disease: a prospective study on symptom diversity and modification of questionnaire application. Dig Dis (Basel, Switzerland) 38(3):188–195. https://doi.org/10.1159/000502796CrossRef Ryan B, Karl-Hermann F, Wolfram B et al (2020) Clinical presentation of gastroesophageal reflux disease: a prospective study on symptom diversity and modification of questionnaire application. Dig Dis (Basel, Switzerland) 38(3):188–195. https://​doi.​org/​10.​1159/​000502796CrossRef
Metadata
Title
An epidemiological survey of gastroesophageal reflux disease at the digestive endoscopy center in Guangzhou
Publication date
01-12-2021
Published in
European Archives of Oto-Rhino-Laryngology / Issue 12/2021
Print ISSN: 0937-4477
Electronic ISSN: 1434-4726
DOI
https://doi.org/10.1007/s00405-021-06999-9

Other articles of this Issue 12/2021

European Archives of Oto-Rhino-Laryngology 12/2021 Go to the issue