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European Archives of Oto-Rhino-Laryngology

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01-02-2019 | Otology

Osteoporosis increases the risk of benign paroxysmal positional vertigo: a nested case–control study using a national sample cohort

Authors: Hyo Geun Choi, Joon Kyu Lee, Il Gyu Kong, Hyun Lim, So Young Kim

Published in: European Archives of Oto-Rhino-Laryngology | Issue 2/2019

Abstract

Introduction

The previous studies suggested an association between osteoporosis and sudden sensory neural hearing loss (SSNHL). The aim of the present study was to evaluate the association between osteoporosis and benign paroxysmal positional vertigo (BPPV).

Materials and methods

Data from the Korean National Health Insurance Service-National Sample Cohort of participants who were ≥ 50 years old were collected from 2002 to 2013. A total of 13,484 BPPV participants were matched with respect to age group, sex, income group, region of residence, hypertension, diabetes, and dyslipidemia to 53,936 controls. In both the BPPV and control groups, the previous histories of osteoporosis were evaluated. Crude (simple) and adjusted odds ratios (ORs) of osteoporosis for BPPV were analyzed using unconditional logistic regression analyses. Subgroup analyses were conducted according to age, sex, and BPPV frequency.

Results

A total of 18.64% (2514/13,464) of the BPPV group and 12.21% (6589/53,936) of the control group had a history of osteoporosis (P < 0.001). The adjusted OR of osteoporosis for BPPV was 1.29 (95% CI = 1.23–1.35, P < 0.001). In the subgroup analysis according to age and sex, the ≥ 70-year-old men did not demonstrate a high adjusted OR of osteoporosis for BPPV. All other age and sex subgroups demonstrated high adjusted ORs of osteoporosis for BPPV.

Conclusions

Osteoporosis increased the risk of BPPV in the population aged ≥ 50 years. The OR of osteoporosis was higher in the frequent BPPV group than in the less frequent BPPV group.

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Title: Osteoporosis increases the risk of benign paroxysmal positional vertigo: a nested case–control study using a national sample cohort
Authors: Hyo Geun Choi
Joon Kyu Lee
Il Gyu Kong
Hyun Lim
So Young Kim
Publication date: 01-02-2019
Publisher: Springer Berlin Heidelberg
Published in: European Archives of Oto-Rhino-Laryngology / Issue 2/2019
Print ISSN: 0937-4477
Electronic ISSN: 1434-4726
DOI: https://doi.org/10.1007/s00405-018-5230-y

At a glance: The ONWARDS insulin icodec trials

Springer Medicine

Osteoporosis increases the risk of benign paroxysmal positional vertigo: a nested case–control study using a national sample cohort

Abstract

Introduction

Materials and methods

Results

Conclusions

At a glance: The ONWARDS insulin icodec trials

Springer Medicine

Abstract

Introduction

Materials and methods

Results

Conclusions

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