Skip to main content
Top
Published in: European Archives of Oto-Rhino-Laryngology 11/2018

01-11-2018 | Editorial

Preoperative diagnostic of parotid gland neoplasms: fine-needle aspiration cytology or core needle biopsy?

Authors: Peter Zbären, Asterios Triantafyllou, Kenneth O. Devaney, Vincent Vander Poorten, Henrik Hellquist, Alessandra Rinaldo, Alfio Ferlito

Published in: European Archives of Oto-Rhino-Laryngology | Issue 11/2018

Login to get access

Abstract

A preoperative cytologic or histologic diagnosis of parotid gland neoplasms is mandatory to decide which surgical procedure would be appropriate. Open biopsies are contraindicated because of the risk of recurrence secondary to tumour cell seeding; furthermore a subsequent curative parotid surgery can be complicated by a previous open biopsy. While fine-needle aspiration cytology (FNAC) was the only preoperative diagnostic procedure to distinguish benign versus malignant neoplasms over the past decades, core needle biopsy (CNB) has been increasingly used over the last few years. This created a debate as to whether FNAC or CNB should be the preoperative procedure of choice. The focus of this editorial is to analyse the advantages and disadvantages of FNAC and CNB, and to discuss which procedure is more appropriate in the preoperative work-up of parotid neoplasms.
Literature
1.
go back to reference Frankenthaler RA, Luna MA, Lee SS, Ang K-K, Byers RM, Guillamondegui OM et al (1991) Prognostic variables in parotid gland cancer. Arch Otolaryngol Head Neck Surg 117(11):1251–1256CrossRef Frankenthaler RA, Luna MA, Lee SS, Ang K-K, Byers RM, Guillamondegui OM et al (1991) Prognostic variables in parotid gland cancer. Arch Otolaryngol Head Neck Surg 117(11):1251–1256CrossRef
2.
go back to reference Spiro RH (1986) Salivary neoplasms: overview of a 35-year experience with 2,807 patients. Head Neck Surg 8(3):177–184CrossRef Spiro RH (1986) Salivary neoplasms: overview of a 35-year experience with 2,807 patients. Head Neck Surg 8(3):177–184CrossRef
3.
go back to reference Gallo O, Franchi A, Bottai GV, Fini-Storchi I, Tesi G, Boddi V (1997) Risk factors for distant metastases from carcinoma of the parotid gland. Cancer 80(5):844–851CrossRef Gallo O, Franchi A, Bottai GV, Fini-Storchi I, Tesi G, Boddi V (1997) Risk factors for distant metastases from carcinoma of the parotid gland. Cancer 80(5):844–851CrossRef
4.
go back to reference Parkin D, Whelan S, Ferlay J, Teppo L, Thomas D (2002) Cancer incidence in five continents. IARC Sci Publ 8(143):1–1240 Parkin D, Whelan S, Ferlay J, Teppo L, Thomas D (2002) Cancer incidence in five continents. IARC Sci Publ 8(143):1–1240
5.
go back to reference Vander Poorten V, Bradley PJ, Takes RP, Rinaldo A, Woolgar JA, Ferlito A (2012) Diagnosis and management of parotid carcinoma with a special focus on recent advances in molecular biology. Head Neck 34(3):429–440CrossRef Vander Poorten V, Bradley PJ, Takes RP, Rinaldo A, Woolgar JA, Ferlito A (2012) Diagnosis and management of parotid carcinoma with a special focus on recent advances in molecular biology. Head Neck 34(3):429–440CrossRef
6.
go back to reference Wong DS (2001) Signs and symptoms of malignant parotid tumours: an objective assessment. J R Coll Surg Edinb 46(2):91–95PubMed Wong DS (2001) Signs and symptoms of malignant parotid tumours: an objective assessment. J R Coll Surg Edinb 46(2):91–95PubMed
7.
go back to reference Freling NJ, Molenaar WM, Vermey A, Mooyaart EL, Panders AK, Annyas AA et al (1992) Malignant parotid tumors: clinical use of MR imaging and histologic correlation. Radiology 185(3):691–696CrossRef Freling NJ, Molenaar WM, Vermey A, Mooyaart EL, Panders AK, Annyas AA et al (1992) Malignant parotid tumors: clinical use of MR imaging and histologic correlation. Radiology 185(3):691–696CrossRef
8.
go back to reference Bartels S, Talbot JM, DiTomasso J, Everts EC, Andersen PE, Wax MK et al (2000) The relative value of fine-needle aspiration and imaging in the preoperative evaluation of parotid masses. Head Neck 22(8):781–786CrossRef Bartels S, Talbot JM, DiTomasso J, Everts EC, Andersen PE, Wax MK et al (2000) The relative value of fine-needle aspiration and imaging in the preoperative evaluation of parotid masses. Head Neck 22(8):781–786CrossRef
9.
go back to reference Barsotti JB, Westesson PL, Coniglio JU (1994) Superiority of magnetic resonance over computed tomography for imaging parotid tumor. Ann Otol Rhinol Laryngol 103(9):737–740CrossRef Barsotti JB, Westesson PL, Coniglio JU (1994) Superiority of magnetic resonance over computed tomography for imaging parotid tumor. Ann Otol Rhinol Laryngol 103(9):737–740CrossRef
10.
go back to reference Zbären P, Zbären S, Caversaccio MD, Stauffer E (2008) Carcinoma ex pleomorphic adenoma: diagnostic difficulty and outcome. Otolaryngol Head Neck Surg 138(5):601–605CrossRef Zbären P, Zbären S, Caversaccio MD, Stauffer E (2008) Carcinoma ex pleomorphic adenoma: diagnostic difficulty and outcome. Otolaryngol Head Neck Surg 138(5):601–605CrossRef
11.
go back to reference Mantsopoulos K, Koch M, Iro H (2017) Extracapsular dissection as sole therapy for small low-grade malignant tumors of the parotid gland. Laryngoscope 127(8):1804–1807CrossRef Mantsopoulos K, Koch M, Iro H (2017) Extracapsular dissection as sole therapy for small low-grade malignant tumors of the parotid gland. Laryngoscope 127(8):1804–1807CrossRef
12.
go back to reference Batsakis J, Sneige N, el-Naggar A (1992) Fine-needle aspiration of salivary glands: it’s utility and effects. Ann Otol Rhinol Laryngol 101:185–188CrossRef Batsakis J, Sneige N, el-Naggar A (1992) Fine-needle aspiration of salivary glands: it’s utility and effects. Ann Otol Rhinol Laryngol 101:185–188CrossRef
13.
go back to reference Witt RL (2002) The significance of the margin in parotid surgery for pleomorphic adenoma. Laryngoscope 112(12):2141–2154CrossRef Witt RL (2002) The significance of the margin in parotid surgery for pleomorphic adenoma. Laryngoscope 112(12):2141–2154CrossRef
14.
go back to reference Vaiman M, Abuita R, Jabarin B (2015) Selective deep lobe parotid surgery for benign tumors. Acta Otolaryngol 135(12):1319–1322CrossRef Vaiman M, Abuita R, Jabarin B (2015) Selective deep lobe parotid surgery for benign tumors. Acta Otolaryngol 135(12):1319–1322CrossRef
15.
go back to reference Hussain A, Murray DP (2005) Preservation of the superficial lobe for deep-lobe parotid tumors: a better aesthetic outcome. Ear Nose Throat J 84(8):518–524PubMed Hussain A, Murray DP (2005) Preservation of the superficial lobe for deep-lobe parotid tumors: a better aesthetic outcome. Ear Nose Throat J 84(8):518–524PubMed
16.
go back to reference McGurk M, Thomas BL, Renehan AG (2003) Extracapsular dissection for clinically benign parotid lumps: reduced morbidity without oncological compromise. Br J Cancer 89(9):1610–1613CrossRef McGurk M, Thomas BL, Renehan AG (2003) Extracapsular dissection for clinically benign parotid lumps: reduced morbidity without oncological compromise. Br J Cancer 89(9):1610–1613CrossRef
17.
go back to reference Zbären P, Vander Poorten V, Witt RL, Woolgar JA, Shaha AR, Triantafyllou A et al (2013) Pleomorphic adenoma of the parotid: formal parotidectomy or limited surgery? Am J Surg 205:109–118CrossRef Zbären P, Vander Poorten V, Witt RL, Woolgar JA, Shaha AR, Triantafyllou A et al (2013) Pleomorphic adenoma of the parotid: formal parotidectomy or limited surgery? Am J Surg 205:109–118CrossRef
18.
go back to reference Quer M, Guntinas-Lichius O, Marchal F, Vander Poorten V, Chevalier D, León X et al (2016) Classification of parotidectomies: a proposal of the European Salivary Gland Society. Eur Arch Oto-Rhino-Laryngol 273(10):3307–3312CrossRef Quer M, Guntinas-Lichius O, Marchal F, Vander Poorten V, Chevalier D, León X et al (2016) Classification of parotidectomies: a proposal of the European Salivary Gland Society. Eur Arch Oto-Rhino-Laryngol 273(10):3307–3312CrossRef
19.
go back to reference Olsen KD, Quer M, de Bree R, Vander Poorten V, Rinaldo A, Ferlito A. Deep lobe parotidectomy—why, when, and how? European Archives of Oto-Rhino-Laryngology. 2017;274(12):4073–4078 Olsen KD, Quer M, de Bree R, Vander Poorten V, Rinaldo A, Ferlito A. Deep lobe parotidectomy—why, when, and how? European Archives of Oto-Rhino-Laryngology. 2017;274(12):4073–4078
20.
go back to reference Schmidt RL, Hall BJ, Wilson ARLL (2011) A systematic review and meta-analysis of the diagnostic accuracy of fine- needle aspiration cytology for parotid gland lesions. Am J Clin Pathol 136(1):45–59CrossRef Schmidt RL, Hall BJ, Wilson ARLL (2011) A systematic review and meta-analysis of the diagnostic accuracy of fine- needle aspiration cytology for parotid gland lesions. Am J Clin Pathol 136(1):45–59CrossRef
21.
go back to reference Liu CC, Jethwa AR, Khariwala SS, Johnson J, Shin JJ (2016) Sensitivity, specificity, and posttest probability of parotid fine-needle aspiration: a systematic review and meta-analysis. Otolaryngol Head Neck Surg 154(1):9–23CrossRef Liu CC, Jethwa AR, Khariwala SS, Johnson J, Shin JJ (2016) Sensitivity, specificity, and posttest probability of parotid fine-needle aspiration: a systematic review and meta-analysis. Otolaryngol Head Neck Surg 154(1):9–23CrossRef
22.
go back to reference Feinstein AJ, Alonso J, Yang SE, John MS (2016) Diagnostic accuracy of fine-needle aspiration for parotid and submandibular gland lesions. Otolaryngol Head Neck Surg 155(3):431–436CrossRef Feinstein AJ, Alonso J, Yang SE, John MS (2016) Diagnostic accuracy of fine-needle aspiration for parotid and submandibular gland lesions. Otolaryngol Head Neck Surg 155(3):431–436CrossRef
23.
go back to reference Eytan DF, Yin LX, Maleki Z, Koch WM, Tufano RP, Eisele DW et al (2018) Utility of preoperative fine needle aspiration in parotid lesions. Laryngoscope 128(2):398–402CrossRef Eytan DF, Yin LX, Maleki Z, Koch WM, Tufano RP, Eisele DW et al (2018) Utility of preoperative fine needle aspiration in parotid lesions. Laryngoscope 128(2):398–402CrossRef
24.
go back to reference Zbären P, Nuyens M, Loosli H, Stauffer E (2004) Diagnostic accuracy of fine-needle aspiration cytology and frozen section in primary parotid carcinoma. Cancer 100(9):1876–1883CrossRef Zbären P, Nuyens M, Loosli H, Stauffer E (2004) Diagnostic accuracy of fine-needle aspiration cytology and frozen section in primary parotid carcinoma. Cancer 100(9):1876–1883CrossRef
25.
go back to reference Zurrida S, Alasio L, Pilotti S, Tradati N, Chiesa F, Bartoli C (1993) Fine-needle aspiration of parotid masses. Cancer 72(8):2306–2311CrossRef Zurrida S, Alasio L, Pilotti S, Tradati N, Chiesa F, Bartoli C (1993) Fine-needle aspiration of parotid masses. Cancer 72(8):2306–2311CrossRef
26.
go back to reference Song IH, Song JS, Sung CO, Roh J-L, Choi S-H, Nam SY et al (2015) Accuracy of core needle biopsy versus fine needle aspiration cytology for diagnosing salivary gland tumors. J Pathol Transl Med 49(2):136–143CrossRef Song IH, Song JS, Sung CO, Roh J-L, Choi S-H, Nam SY et al (2015) Accuracy of core needle biopsy versus fine needle aspiration cytology for diagnosing salivary gland tumors. J Pathol Transl Med 49(2):136–143CrossRef
27.
go back to reference Que Hee CG, Perry CF (2001) Fine-needle aspiration cytology of parotid tumours: is it useful? ANZ J Surg 71(6):345–348CrossRef Que Hee CG, Perry CF (2001) Fine-needle aspiration cytology of parotid tumours: is it useful? ANZ J Surg 71(6):345–348CrossRef
28.
go back to reference Zbären P, Guélat D, Loosli H, Stauffer E (2008) Parotid tumors: fine-needle aspiration and/or frozen section. Otolaryngol Head Neck Surg 139(6):811–815CrossRef Zbären P, Guélat D, Loosli H, Stauffer E (2008) Parotid tumors: fine-needle aspiration and/or frozen section. Otolaryngol Head Neck Surg 139(6):811–815CrossRef
29.
go back to reference Shah KSV, Ethunandan M (2016) Tumour seeding after fine-needle aspiration and core biopsy of the head and neck—a systematic review. Br J Oral Maxillofac Surg 54:260–265CrossRef Shah KSV, Ethunandan M (2016) Tumour seeding after fine-needle aspiration and core biopsy of the head and neck—a systematic review. Br J Oral Maxillofac Surg 54:260–265CrossRef
30.
go back to reference Polyzos SA, Anastasilakis AD (2010) A systematic review of cases reporting needle tract seeding following thyroid fine needle biopsy. World J Surg 34:844–851CrossRef Polyzos SA, Anastasilakis AD (2010) A systematic review of cases reporting needle tract seeding following thyroid fine needle biopsy. World J Surg 34:844–851CrossRef
31.
go back to reference Tung WC, Huang YJ, Leung SW, Kuo FY, Tung H, Wang JH et al (2007) Incidence of needle tract seeding and responses of soft tissue metastasis by hepatocellular carcinoma postradiotherapy. Liver Int 27(2):192–200CrossRef Tung WC, Huang YJ, Leung SW, Kuo FY, Tung H, Wang JH et al (2007) Incidence of needle tract seeding and responses of soft tissue metastasis by hepatocellular carcinoma postradiotherapy. Liver Int 27(2):192–200CrossRef
32.
go back to reference Eisele DW, Sherman ME, Koch WM, Richtsmeier WJ, Wu AY, Erozan YS (1992) Utility of immediate on-site cytopathological procurement and evaluation in fine needle aspiration biopsy of head and neck masses. Laryngoscope 102(12):1328–1330CrossRef Eisele DW, Sherman ME, Koch WM, Richtsmeier WJ, Wu AY, Erozan YS (1992) Utility of immediate on-site cytopathological procurement and evaluation in fine needle aspiration biopsy of head and neck masses. Laryngoscope 102(12):1328–1330CrossRef
33.
go back to reference Wu M, Burstein DE, Yuan S, Nurse LA, Szporn AH, Zhang D et al (2006) A comparative study of 200 fine needle aspiration biopsies performed by clinicians and cytopathologists. Laryngoscope 116(7):1212–1215CrossRef Wu M, Burstein DE, Yuan S, Nurse LA, Szporn AH, Zhang D et al (2006) A comparative study of 200 fine needle aspiration biopsies performed by clinicians and cytopathologists. Laryngoscope 116(7):1212–1215CrossRef
34.
go back to reference Schmidt RL, Hall BJ, Layfield LJ (2011) A systematic review and meta-analysis of the diagnostic accuracy of ultrasound-guided core needle biopsy for salivary gland lesions. Am J Clin Pathol 136:516–526CrossRef Schmidt RL, Hall BJ, Layfield LJ (2011) A systematic review and meta-analysis of the diagnostic accuracy of ultrasound-guided core needle biopsy for salivary gland lesions. Am J Clin Pathol 136:516–526CrossRef
35.
go back to reference Breeze J, Andi A, Williams MD, Howlett DC (2009) The use of fine needle core biopsy under ultrasound guidance in the diagnosis of a parotid mass. Br J Oral Maxillofac Surg 47(1):78–79CrossRef Breeze J, Andi A, Williams MD, Howlett DC (2009) The use of fine needle core biopsy under ultrasound guidance in the diagnosis of a parotid mass. Br J Oral Maxillofac Surg 47(1):78–79CrossRef
36.
go back to reference Carbone A, Ferlito A, Devaney KO, Rinaldo A (2008) Ultrasound-guided core-needle biopsy: Is it effective in the diagnosis of suspected lymphomas presenting in the head and neck? J Surg Oncol 98(1):4–5CrossRef Carbone A, Ferlito A, Devaney KO, Rinaldo A (2008) Ultrasound-guided core-needle biopsy: Is it effective in the diagnosis of suspected lymphomas presenting in the head and neck? J Surg Oncol 98(1):4–5CrossRef
37.
go back to reference Kim HJ, Kim JS (2018) Ultrasound-guided core needle biopsy in salivary glands: a meta-analysis. Laryngoscope 128(1):118–125CrossRef Kim HJ, Kim JS (2018) Ultrasound-guided core needle biopsy in salivary glands: a meta-analysis. Laryngoscope 128(1):118–125CrossRef
38.
go back to reference Witt BL, Schmidt RL (2014) Ultrasound-guided core needle biopsy of salivary gland lesions: a systematic review and meta-analysis. Laryngoscope 124(3):695–700CrossRef Witt BL, Schmidt RL (2014) Ultrasound-guided core needle biopsy of salivary gland lesions: a systematic review and meta-analysis. Laryngoscope 124(3):695–700CrossRef
39.
go back to reference Yamaguchi KT, Strong MS, Shapshay SM, Soto E (1979) Seeding of parotid carcinoma along Vim-Silverman needle tract. J Otolaryngol 8(1):49–52PubMed Yamaguchi KT, Strong MS, Shapshay SM, Soto E (1979) Seeding of parotid carcinoma along Vim-Silverman needle tract. J Otolaryngol 8(1):49–52PubMed
40.
go back to reference Kraft M, Laeng H, Schmuziger N, Arnoux A, Gürtler N (2008) Comparison of ultrasound-guided core-needle biopsy and fine-needle aspiration in the assessment of head and neck lesions. Head Neck 30(11):1457–1463CrossRef Kraft M, Laeng H, Schmuziger N, Arnoux A, Gürtler N (2008) Comparison of ultrasound-guided core-needle biopsy and fine-needle aspiration in the assessment of head and neck lesions. Head Neck 30(11):1457–1463CrossRef
41.
go back to reference Novoa E, Gürtler N, Arnoux A, Kraft M (2016) Diagnostic value of core needle biopsy and fine-needle aspiration in salivary gland lesions. Head Neck 38(suppl 1):E346–E352CrossRef Novoa E, Gürtler N, Arnoux A, Kraft M (2016) Diagnostic value of core needle biopsy and fine-needle aspiration in salivary gland lesions. Head Neck 38(suppl 1):E346–E352CrossRef
42.
go back to reference Kesse KW, Manjaly G, Violaris N, Howlett DC (2002) Ultrasound-guided biopsy in the evaluation of focal lesions and diffuse swelling of the parotid gland. Br J Oral Maxillofac Surg 40(5):384–388CrossRef Kesse KW, Manjaly G, Violaris N, Howlett DC (2002) Ultrasound-guided biopsy in the evaluation of focal lesions and diffuse swelling of the parotid gland. Br J Oral Maxillofac Surg 40(5):384–388CrossRef
43.
go back to reference Douville NJ, Bradford CR (2013) Comparison of ultrasound-guided core biopsy versus fine-needle aspiration biopsy in the evaluation of salivary gland lesions. Head Neck 35(11):1657–1661CrossRef Douville NJ, Bradford CR (2013) Comparison of ultrasound-guided core biopsy versus fine-needle aspiration biopsy in the evaluation of salivary gland lesions. Head Neck 35(11):1657–1661CrossRef
44.
go back to reference Eom HJ, Lee JH, Ko MS, Choi YJ, Yoon RG, Cho KJ et al (2015) Comparison of fine-needle aspiration and core needle biopsy under ultrasonographic guidance for detecting malignancy and for the tissue-specific diagnosis of salivary gland tumors. Am J Neuroradiol 36(6):1188–1193CrossRef Eom HJ, Lee JH, Ko MS, Choi YJ, Yoon RG, Cho KJ et al (2015) Comparison of fine-needle aspiration and core needle biopsy under ultrasonographic guidance for detecting malignancy and for the tissue-specific diagnosis of salivary gland tumors. Am J Neuroradiol 36(6):1188–1193CrossRef
45.
go back to reference Huang YC, Wu C, Lin G, Chuang WY, Yeow KM, Wan YL (2012) Comparison of ultrasonographically guided fine-needle aspiration and core needle biopsy in the diagnosis of parotid masses. J Clin Ultrasound 40(4):189–194CrossRef Huang YC, Wu C, Lin G, Chuang WY, Yeow KM, Wan YL (2012) Comparison of ultrasonographically guided fine-needle aspiration and core needle biopsy in the diagnosis of parotid masses. J Clin Ultrasound 40(4):189–194CrossRef
46.
go back to reference Olsen KD, Moore EJ, Lewis JE (2013) Frozen section pathology for decision making in parotid surgery. JAMA Otolaryngol Head Neck Surg 139(12):1275–1278CrossRef Olsen KD, Moore EJ, Lewis JE (2013) Frozen section pathology for decision making in parotid surgery. JAMA Otolaryngol Head Neck Surg 139(12):1275–1278CrossRef
47.
go back to reference Skalova A, Stenman G, Simpson RHW, Hellquist H, Slouka D, Svoboda T et al (2018) The role of molecular testing in the differential diagnosis of salivary gland carcinomas. Am J Surg Pathol 42(2):e11–e27CrossRef Skalova A, Stenman G, Simpson RHW, Hellquist H, Slouka D, Svoboda T et al (2018) The role of molecular testing in the differential diagnosis of salivary gland carcinomas. Am J Surg Pathol 42(2):e11–e27CrossRef
48.
go back to reference Evrard SM, Meilleroux J, Daniel G, Basset C, Lacoste-Collin L, Vergez S et al (2017) Use of fluorescent in-situ hybridisation in salivary gland cytology: a powerful diagnostic tool. Cytopathology 28(4):312–320CrossRef Evrard SM, Meilleroux J, Daniel G, Basset C, Lacoste-Collin L, Vergez S et al (2017) Use of fluorescent in-situ hybridisation in salivary gland cytology: a powerful diagnostic tool. Cytopathology 28(4):312–320CrossRef
49.
go back to reference Schmidt RL, Jedrzkiewicz JD, Allred RJ, Matsuoka S, Witt BL (2014) Verification bias in diagnostic accuracy studies for fine- and core needle biopsy of salivary gland lesions in otolaryngology journals: a systematic review and analysis. Head Neck 36(11):1654–1661CrossRef Schmidt RL, Jedrzkiewicz JD, Allred RJ, Matsuoka S, Witt BL (2014) Verification bias in diagnostic accuracy studies for fine- and core needle biopsy of salivary gland lesions in otolaryngology journals: a systematic review and analysis. Head Neck 36(11):1654–1661CrossRef
Metadata
Title
Preoperative diagnostic of parotid gland neoplasms: fine-needle aspiration cytology or core needle biopsy?
Authors
Peter Zbären
Asterios Triantafyllou
Kenneth O. Devaney
Vincent Vander Poorten
Henrik Hellquist
Alessandra Rinaldo
Alfio Ferlito
Publication date
01-11-2018
Publisher
Springer Berlin Heidelberg
Published in
European Archives of Oto-Rhino-Laryngology / Issue 11/2018
Print ISSN: 0937-4477
Electronic ISSN: 1434-4726
DOI
https://doi.org/10.1007/s00405-018-5131-0

Other articles of this Issue 11/2018

European Archives of Oto-Rhino-Laryngology 11/2018 Go to the issue