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European Archives of Oto-Rhino-Laryngology

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01-12-2016 | Head and Neck

Management of recurrent head and neck cancer: variables related to salvage surgery

Authors: Laura Gañán, Montserrat López, Jacinto García, Eduard Esteller, Miquel Quer, Xavier León

Published in: European Archives of Oto-Rhino-Laryngology | Issue 12/2016

Abstract

After a local and/or regional recurrence of head and neck squamous cell carcinoma (HNSCC) not all patients are candidates to salvage treatment. The objective of this study was to identify the variables related to performance of salvage surgery with curative intent in these patients. We performed a retrospective study of 1088 HNSCC patients with a local and/or regional recurrence. According to a multivariate analysis, the variables related to performance of salvage surgery were the Karnofsky index, the location and extension of the primary tumor, the initial treatment, the disease-free interval between treatment of the initial tumor and diagnosis of the recurrence, and the year the recurrence was diagnosed. Considering salvage surgery as the dependent variable, the results of a recursive partitioning analysis defined four categories of patients in function of the category of local and regional extension of the initial tumor, the location of the primary tumor, the initial treatment and the disease-free interval between treatment of the initial tumor and diagnosis of the recurrence.

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Title: Management of recurrent head and neck cancer: variables related to salvage surgery
Authors: Laura Gañán
Montserrat López
Jacinto García
Eduard Esteller
Miquel Quer
Xavier León
Publication date: 01-12-2016
Publisher: Springer Berlin Heidelberg
Published in: European Archives of Oto-Rhino-Laryngology / Issue 12/2016
Print ISSN: 0937-4477
Electronic ISSN: 1434-4726
DOI: https://doi.org/10.1007/s00405-016-4093-3

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Management of recurrent head and neck cancer: variables related to salvage surgery

Abstract

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