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Published in: European Archives of Oto-Rhino-Laryngology 5/2016

01-05-2016 | Case Report

Esthesioneuroblastoma with large intracranial extension treated with Induction chemotherapy, de-bulking surgery and image guided intensity modulated radiotherapy

Authors: Prashanth Giridhar, Supriya Mallick, M. A. Laviraj, Suman Bhasker

Published in: European Archives of Oto-Rhino-Laryngology | Issue 5/2016

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Abstract

Introduction

Esthesioneuroblastoma is a rare tumour of the sino-nasal tract. One-third cases present with intracranial extension. However, treatment options are limited for such cases.

Methodology

We herein report a case with large intracranial extension treated with Induction chemotherapy, de-bulking surgery, and image guided intensity modulated radiotherapy.

Results

The patient was treated with IGIMRT technique to a dose of 64 Gy in 32 fractions. Cone bean CT verification was done twice a week to eliminate set up error. The patient achieved complete resolution of the disease and was disease free 6 months after completion of treatment.

Conclusion

IGIMRT even after a de-bulking surgery may help to achieve long-term disease control for patients with large intracranial extension with minimal morbidity.
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Metadata
Title
Esthesioneuroblastoma with large intracranial extension treated with Induction chemotherapy, de-bulking surgery and image guided intensity modulated radiotherapy
Authors
Prashanth Giridhar
Supriya Mallick
M. A. Laviraj
Suman Bhasker
Publication date
01-05-2016
Publisher
Springer Berlin Heidelberg
Published in
European Archives of Oto-Rhino-Laryngology / Issue 5/2016
Print ISSN: 0937-4477
Electronic ISSN: 1434-4726
DOI
https://doi.org/10.1007/s00405-015-3672-z

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