Skip to main content
Top
Published in: European Archives of Oto-Rhino-Laryngology 5/2016

01-05-2016 | Head and Neck

The impact of surgical technique on neck dissection nodal yield: making a difference

Authors: Balazs B. Lörincz, Felix Langwieder, Nikolaus Möckelmann, Susanne Sehner, Rainald Knecht

Published in: European Archives of Oto-Rhino-Laryngology | Issue 5/2016

Login to get access

Abstract

The nodal yield of neck dissections is an independent prognostic factor in several types of head and neck cancer. The authors aimed to determine whether the applied dissection technique has a significant impact on nodal yield. This is a single-institution, prospective study with internal control group (level of evidence: 2A). Data of 150 patients undergoing 223 neck dissections between February 2011 and March 2013 have been collected in a comprehensive cancer centre. Eighty-two patients underwent neck dissection with unwrapping the cervical fascia from lateral to medial, while 68 patients were operated without specifically unwrapping the fascia, in a caudal to cranial fashion. The standardised, horizontal neck dissection technique along the fascial planes resulted in a significantly higher nodal count in Levels I, II, III and IV, as well as in terms of overall nodal yield (mean: n = 22.53) than that of the vertical dissection applied in the control group (mean: n = 15.00). This is the first publication showing a direct correlation between neck dissection nodal yield and surgical technique. Therefore, it is paramount to optimise the applied surgical concept to maximise the oncological benefit.
Literature
1.
go back to reference Le Voyer TE, Sigurdson ER, Hanlon AL et al (2003) Colon cancer survival is associated with increasing number of lymph nodes analyzed: a secondary survey of intergroup trial INT-0089. J Clin Oncol Off J Am Soc Clin Oncol 21:2912–2919CrossRef Le Voyer TE, Sigurdson ER, Hanlon AL et al (2003) Colon cancer survival is associated with increasing number of lymph nodes analyzed: a secondary survey of intergroup trial INT-0089. J Clin Oncol Off J Am Soc Clin Oncol 21:2912–2919CrossRef
2.
go back to reference Chen SL, Bilchik AJ (2006) More extensive nodal dissection improves survival for stages I to III of colon cancer: a population-based study. Ann Surg 244:602–610PubMedPubMedCentral Chen SL, Bilchik AJ (2006) More extensive nodal dissection improves survival for stages I to III of colon cancer: a population-based study. Ann Surg 244:602–610PubMedPubMedCentral
3.
go back to reference Cianchi F, Palomba A, Boddi V et al (2002) Lymph node recovery from colorectal tumor specimens: recommendation for a minimum number of lymph nodes to be examined. World J Surg 26:384–389CrossRefPubMed Cianchi F, Palomba A, Boddi V et al (2002) Lymph node recovery from colorectal tumor specimens: recommendation for a minimum number of lymph nodes to be examined. World J Surg 26:384–389CrossRefPubMed
4.
go back to reference Brunocilla E, Pernetti R, Schiavina R et al (2013) The number of nodes removed as well as the template of the dissection is independently correlated to cancer-specific survival after radical cystectomy for muscle-invasive bladder cancer. Int Urol Nephrol 45:711–719CrossRefPubMed Brunocilla E, Pernetti R, Schiavina R et al (2013) The number of nodes removed as well as the template of the dissection is independently correlated to cancer-specific survival after radical cystectomy for muscle-invasive bladder cancer. Int Urol Nephrol 45:711–719CrossRefPubMed
5.
go back to reference Herr HW, Bochner BH, Dalbagni G et al (2002) Impact of the number of lymph nodes retrieved on outcome in patients with muscle invasive bladder cancer. J Urol 167:1295–1298CrossRefPubMed Herr HW, Bochner BH, Dalbagni G et al (2002) Impact of the number of lymph nodes retrieved on outcome in patients with muscle invasive bladder cancer. J Urol 167:1295–1298CrossRefPubMed
6.
go back to reference Konety BR, Joslyn SA, O’Donnell MA (2003) Extent of pelvic lymphadenectomy and its impact on outcome in patients diagnosed with bladder cancer: analysis of data from the surveillance, epidemiology and end results Program data base. J Urol 169:946–950CrossRefPubMed Konety BR, Joslyn SA, O’Donnell MA (2003) Extent of pelvic lymphadenectomy and its impact on outcome in patients diagnosed with bladder cancer: analysis of data from the surveillance, epidemiology and end results Program data base. J Urol 169:946–950CrossRefPubMed
7.
go back to reference Briganti A, Chun FK, Salonia A et al (2007) Critical assessment of ideal nodal yield at pelvic lymphadenectomy to accurately diagnose prostate cancer nodal metastasis in patients undergoing radical retropubic prostatectomy. Urology 69:147–151CrossRefPubMed Briganti A, Chun FK, Salonia A et al (2007) Critical assessment of ideal nodal yield at pelvic lymphadenectomy to accurately diagnose prostate cancer nodal metastasis in patients undergoing radical retropubic prostatectomy. Urology 69:147–151CrossRefPubMed
8.
go back to reference Johnson TV, Hsiao W, Delman KA et al (2010) Extensive inguinal lymphadenectomy improves overall 5-year survival in penile cancer patients: results from the surveillance, epidemiology, and end results program. Cancer 116:2960–2966CrossRefPubMed Johnson TV, Hsiao W, Delman KA et al (2010) Extensive inguinal lymphadenectomy improves overall 5-year survival in penile cancer patients: results from the surveillance, epidemiology, and end results program. Cancer 116:2960–2966CrossRefPubMed
9.
go back to reference Peyre CG, Hagen JA, DeMeester SR et al (2008) The number of lymph nodes removed predicts survival in esophageal cancer: an international study on the impact of extent of surgical resection. Ann Surg 248:549–556CrossRefPubMed Peyre CG, Hagen JA, DeMeester SR et al (2008) The number of lymph nodes removed predicts survival in esophageal cancer: an international study on the impact of extent of surgical resection. Ann Surg 248:549–556CrossRefPubMed
10.
go back to reference Volpe CM, Driscoll DL, Douglass HO Jr (2000) Outcome of patients with proximal gastric cancer depends on extent of resection and number of resected lymph nodes. Ann Surg Oncol 7:139–144CrossRefPubMed Volpe CM, Driscoll DL, Douglass HO Jr (2000) Outcome of patients with proximal gastric cancer depends on extent of resection and number of resected lymph nodes. Ann Surg Oncol 7:139–144CrossRefPubMed
11.
go back to reference Weir L, Speers C, D’Yachkova Y, Olivotto IA (2002) Prognostic significance of the number of axillary lymph nodes removed in patients with node-negative breast cancer. J Clin Oncol Off J Am Soc Clin Oncol 20:1793–1799CrossRef Weir L, Speers C, D’Yachkova Y, Olivotto IA (2002) Prognostic significance of the number of axillary lymph nodes removed in patients with node-negative breast cancer. J Clin Oncol Off J Am Soc Clin Oncol 20:1793–1799CrossRef
12.
go back to reference Jaber JJ, Zender CA, Mehta V et al (2013) A multi-institutional investigation of the prognostic value of lymph nodal yield in advanced stage oral cavity squamous cell carcinoma (OCSCC). Head Neck 36(10):1446–1452 Jaber JJ, Zender CA, Mehta V et al (2013) A multi-institutional investigation of the prognostic value of lymph nodal yield in advanced stage oral cavity squamous cell carcinoma (OCSCC). Head Neck 36(10):1446–1452
13.
go back to reference Pereira JA, Jimeno J, Miquel J et al (2005) Nodal yield, morbidity, and recurrence after central neck dissection for papillary thyroid carcinoma. Surgery 138:1095–1100 (discussion 1100–1091)CrossRefPubMed Pereira JA, Jimeno J, Miquel J et al (2005) Nodal yield, morbidity, and recurrence after central neck dissection for papillary thyroid carcinoma. Surgery 138:1095–1100 (discussion 1100–1091)CrossRefPubMed
14.
go back to reference Vas Nunes JH, Clark JR, Gao K et al (2013) Prognostic implications of lymph node yield and lymph node ratio in papillary thyroid carcinoma. Thyroid Off J Am Thyroid Assoc 23:811–816CrossRef Vas Nunes JH, Clark JR, Gao K et al (2013) Prognostic implications of lymph node yield and lymph node ratio in papillary thyroid carcinoma. Thyroid Off J Am Thyroid Assoc 23:811–816CrossRef
15.
go back to reference Ebrahimi A, Zhang WJ, Gao K, Clark JR (2011) Nodal yield and survival in oral squamous cancer: defining the standard of care. Cancer 117:2917–2925CrossRefPubMed Ebrahimi A, Zhang WJ, Gao K, Clark JR (2011) Nodal yield and survival in oral squamous cancer: defining the standard of care. Cancer 117:2917–2925CrossRefPubMed
16.
go back to reference Patel SG, Amit M, Yen TC et al (2013) Lymph node density in oral cavity cancer: results of the International Consortium for Outcomes Research. Br J Cancer 109:2087–2095CrossRefPubMedPubMedCentral Patel SG, Amit M, Yen TC et al (2013) Lymph node density in oral cavity cancer: results of the International Consortium for Outcomes Research. Br J Cancer 109:2087–2095CrossRefPubMedPubMedCentral
17.
go back to reference Agrama MT, Reiter D, Cunnane MF (2003) Nodal yield in neck dissection and the likelihood of metastases. Otolaryngol Head Neck Surg Off J Am Acad Otolaryngol Head Neck Surg 128:185–190CrossRef Agrama MT, Reiter D, Cunnane MF (2003) Nodal yield in neck dissection and the likelihood of metastases. Otolaryngol Head Neck Surg Off J Am Acad Otolaryngol Head Neck Surg 128:185–190CrossRef
18.
go back to reference Ebrahimi A, Clark JR, Amit M et al. (2014) Minimum nodal yield in oral squamous cell carcinoma: defining the standard of care in a multicenter international pooled validation study. Ann Surg Oncol Ebrahimi A, Clark JR, Amit M et al. (2014) Minimum nodal yield in oral squamous cell carcinoma: defining the standard of care in a multicenter international pooled validation study. Ann Surg Oncol
19.
go back to reference Yu Y, Wang XL, Xu ZG, Li Q (2013) Prognostic value of the number of lymph nodes retrieved after selective neck dissection in hypopharyngeal squamous carcinoma. Zhonghua er bi yan hou tou jing wai ke za zhi Chin J Otorhinolaryngol Head Neck Surg 48:148–153 Yu Y, Wang XL, Xu ZG, Li Q (2013) Prognostic value of the number of lymph nodes retrieved after selective neck dissection in hypopharyngeal squamous carcinoma. Zhonghua er bi yan hou tou jing wai ke za zhi Chin J Otorhinolaryngol Head Neck Surg 48:148–153
20.
go back to reference Bhattacharyya N (1998) The effects of more conservative neck dissections and radiotherapy on nodal yields from the neck. Archiv Otolaryngol Head Neck Surg 124:412–416CrossRef Bhattacharyya N (1998) The effects of more conservative neck dissections and radiotherapy on nodal yields from the neck. Archiv Otolaryngol Head Neck Surg 124:412–416CrossRef
21.
go back to reference Gavilán J (2002) Functional and selective neck dissection. Thieme, New York Gavilán J (2002) Functional and selective neck dissection. Thieme, New York
22.
go back to reference Ferlito A, Gavilan J, Buckley JG et al (2001) Functional neck dissection: fact and fiction. Head Neck 23(9):804–808CrossRefPubMed Ferlito A, Gavilan J, Buckley JG et al (2001) Functional neck dissection: fact and fiction. Head Neck 23(9):804–808CrossRefPubMed
23.
go back to reference Gavilan J, Gavilan C, Herranz J (1992) Functional neck dissection: three decades of controversy. Ann Otol Rhinol Laryngol 101:339–341CrossRefPubMed Gavilan J, Gavilan C, Herranz J (1992) Functional neck dissection: three decades of controversy. Ann Otol Rhinol Laryngol 101:339–341CrossRefPubMed
24.
go back to reference Kerawala CJ, Bisase B, Hopper A (2009) Is total nodal yield in neck dissections influenced by the method of specimen presentation to the pathologist? Br J Oral maxillofac Surg 47:360–362CrossRefPubMed Kerawala CJ, Bisase B, Hopper A (2009) Is total nodal yield in neck dissections influenced by the method of specimen presentation to the pathologist? Br J Oral maxillofac Surg 47:360–362CrossRefPubMed
25.
go back to reference Gavilan C, Gavilan J (1989) Five-year results of functional neck dissection for cancer of the larynx. Archiv Otolaryngol Head Neck Surg 115:1193–1196CrossRef Gavilan C, Gavilan J (1989) Five-year results of functional neck dissection for cancer of the larynx. Archiv Otolaryngol Head Neck Surg 115:1193–1196CrossRef
26.
go back to reference Norling R, Therkildsen MH, Bradley PJ et al (2013) Nodal yield in selective neck dissection. Acta Otolaryngol 133:965–971CrossRefPubMed Norling R, Therkildsen MH, Bradley PJ et al (2013) Nodal yield in selective neck dissection. Acta Otolaryngol 133:965–971CrossRefPubMed
27.
go back to reference Friedman M, Lim JW, Dickey W et al (1999) Quantification of lymph nodes in selective neck dissection. Laryngoscope 109:368–370CrossRefPubMed Friedman M, Lim JW, Dickey W et al (1999) Quantification of lymph nodes in selective neck dissection. Laryngoscope 109:368–370CrossRefPubMed
28.
go back to reference Morton RP, Gray L, Tandon DA et al (2009) Efficacy of neck dissection: are surgical volumes important? Laryngoscope 119:1147–1152CrossRefPubMed Morton RP, Gray L, Tandon DA et al (2009) Efficacy of neck dissection: are surgical volumes important? Laryngoscope 119:1147–1152CrossRefPubMed
Metadata
Title
The impact of surgical technique on neck dissection nodal yield: making a difference
Authors
Balazs B. Lörincz
Felix Langwieder
Nikolaus Möckelmann
Susanne Sehner
Rainald Knecht
Publication date
01-05-2016
Publisher
Springer Berlin Heidelberg
Published in
European Archives of Oto-Rhino-Laryngology / Issue 5/2016
Print ISSN: 0937-4477
Electronic ISSN: 1434-4726
DOI
https://doi.org/10.1007/s00405-015-3601-1

Other articles of this Issue 5/2016

European Archives of Oto-Rhino-Laryngology 5/2016 Go to the issue