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European Archives of Oto-Rhino-Laryngology
Published in: European Archives of Oto-Rhino-Laryngology 6/2014

01-06-2014 | Rhinology

The impact and prospect of traumatic brain injury on olfactory function: a cross-sectional and prospective study

Authors: Volker Gudziol, Irene Hoenck, Basile Landis, Dino Podlesek, Maria Bayn, Thomas Hummel

Published in: European Archives of Oto-Rhino-Laryngology | Issue 6/2014

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Abstract

Traumatic brain injury (TBI) can cause olfactory loss. The aim of this cross-sectional and prospective study was to determine the prevalence of olfactory loss among 110 patients with TBI within 3 months after the trauma. In 81 patients (“cross-sectional”-group), olfactory function could be measured using the validated “Sniffin’ Sticks” test for odor threshold and odor identification. In addition, the prospective change of olfactory function was studied in 36 patients (“follow-up”-group) by means of a validated odor threshold, discrimination and identification test. Olfactory function was significantly better in patients with TBI I° compared to individuals with TBI II° and III°. Clinically significant improvement of olfactory function was found in 36 % of the patients, most frequently during the first 6 months after the injury, in a median follow-up interval of 21 months. TBI I° has in general no major effect on olfaction. In contrast, patients with TBI II° and III° exhibit smell loss in 57 %. Chances for olfactory recovery were highest within the first 6 months after the trauma.
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Metadata
Title
The impact and prospect of traumatic brain injury on olfactory function: a cross-sectional and prospective study
Authors
Volker Gudziol
Irene Hoenck
Basile Landis
Dino Podlesek
Maria Bayn
Thomas Hummel
Publication date
01-06-2014
Publisher
Springer Berlin Heidelberg
Published in
European Archives of Oto-Rhino-Laryngology / Issue 6/2014
Print ISSN: 0937-4477
Electronic ISSN: 1434-4726
DOI
https://doi.org/10.1007/s00405-013-2687-6

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