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Published in: European Archives of Oto-Rhino-Laryngology 8/2013

Open Access 01-08-2013 | Head and Neck

Results of transoral laser microsurgery in 102 patients with squamous cell carcinoma of the tonsil

Authors: Martin Canis, Alexios Martin, Martina Kron, Alexandra Konstantinou, Friedrich Ihler, Hendrik A. Wolff, Christoph Matthias, Wolfgang Steiner

Published in: European Archives of Oto-Rhino-Laryngology | Issue 8/2013

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Abstract

The objective of this study is to assess the feasibility of transoral laser microsurgery (TLM) in the treatment of squamous cell cancer of the tonsil and to report the oncological and functional outcomes, using retrospective chart review in the setting of single-institute, academic tertiary referral center. Between October 1987 and December 2006, 102 patients were eligible for this study, mostly suffering from advanced disease: 13 % presented with stage I and II (UICC/AJCC 2002) tumors and 87 % with stages III and IVa. The median follow-up was 63 months. All patients were treated by TLM with (or without) neck dissection (95 %) and with (66 %) postoperative radiotherapy. Overall survival, recurrence-free survival, disease-free survival, local control and loco-regional control were analyzed as end points. Rate of tracheotomies, postoperative complications and swallowing function were also analyzed. 5-year Kaplan–Meier local and loco-regional control was 78 % for pT1 and pT2 and 75 % for pT3 and pT4a tumors. 5-year Kaplan–Meier disease-free survival, recurrence-free survival, and overall survival and was 74, 64 and 59 % for stage I and II, 68, 60 and 56 % for stage III and IVa, respectively. Our data supports the conclusion, that TLM should be considered as a therapeutic option for the treatment of cancer of the tonsil. The oncological and functional results are comparable to any other treatment regimen, while the morbidity and complications tend to be lower.
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Metadata
Title
Results of transoral laser microsurgery in 102 patients with squamous cell carcinoma of the tonsil
Authors
Martin Canis
Alexios Martin
Martina Kron
Alexandra Konstantinou
Friedrich Ihler
Hendrik A. Wolff
Christoph Matthias
Wolfgang Steiner
Publication date
01-08-2013
Publisher
Springer Berlin Heidelberg
Published in
European Archives of Oto-Rhino-Laryngology / Issue 8/2013
Print ISSN: 0937-4477
Electronic ISSN: 1434-4726
DOI
https://doi.org/10.1007/s00405-012-2335-6

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