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Published in: European Archives of Oto-Rhino-Laryngology 1/2012

01-01-2012 | Rhinology

Nose- and sinus-related quality of life and GERD

Authors: Elin-Johanne Katle, Harald Hart, Thomas Kjærgaard, Jan Terje Kvaløy, Sverre Karmhus Steinsvåg

Published in: European Archives of Oto-Rhino-Laryngology | Issue 1/2012

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Abstract

Though some data indicate an association between gastroesophageal reflux disease (GERD) and upper airway inflammatory disease, a connection between GERD and chronic rhinosinusitis (CRS) is a matter of controversy in today’s medicine. The aim of this study was to examine whether patients with GERD have a different nose- and sinus-related quality of life compared to a control group. A total of 77 patients with GERD diagnosed by gastroscopy were evaluated according to their nose- and sinus-related quality of life. It was scored using the Sino-Nasal Outcome Test-20 (SNOT-20). Total SNOT-20 score was compared with a control group consisting of 480 teachers. The average total SNOT-20 score in patients with GERD was 22.1, and in the control group 9.4 (p < 0.005). In the patient group, the median was 17.0 and standard deviation 18.4 corresponding to 5.0 and 11.5 in the controls. The 95% confidence interval in the patient group was (18.0, 26.3), and (8.3, 10.4) in the control group. Patients with GERD have a reduced nose- and sinus-related quality of life compared to a control group based on the fact that they have a significantly higher total SNOT-20 score than the controls. Accordingly, this study indicates that there is a causal relationship between GERD and CRS.
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Metadata
Title
Nose- and sinus-related quality of life and GERD
Authors
Elin-Johanne Katle
Harald Hart
Thomas Kjærgaard
Jan Terje Kvaløy
Sverre Karmhus Steinsvåg
Publication date
01-01-2012
Publisher
Springer-Verlag
Published in
European Archives of Oto-Rhino-Laryngology / Issue 1/2012
Print ISSN: 0937-4477
Electronic ISSN: 1434-4726
DOI
https://doi.org/10.1007/s00405-011-1675-y

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