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European Archives of Oto-Rhino-Laryngology

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01-04-2010 | Editorial

Response evaluation in head and neck oncology

Authors: Robert Mandic, Jochen A. Werner

Published in: European Archives of Oto-Rhino-Laryngology | Issue 4/2010

Excerpt

In this issue you will find the review article “assay-based response evaluation in head and neck oncology: requirements for better decision making” by Dietz and co-workers [1]. This interesting review addresses a major issue in head and neck cancer therapy. A major problem in the treatment of head and neck cancers, particularly head and neck squamous cell carcinomas (HNSCCs), accounting for over 90% of all malignancies in this area, is unpredictable resistance to chemotherapy and failure after multimodality treatment in general. Being able to identify responders and non-responders prior to therapy induction is therefore of utmost importance. …

Dietz A, Boehm A, Horn IS, Kruber P, Bechmann I, Golusinski W, Niederwieser D, Dollner R, Remmerbach TW, Wittekind C, Dietzsch S, Hildebrandt G, Wichmann G (2009) Assay based response evaluation in head and neck oncology—requirements for better decision making. Eur Arch Otorhinolaryngol. doi:10.1007/s00405-009-1191-5

Cree IA (2009) Chemosensitivity and chemoresistance testing in ovarian cancer. Curr Opin Obstet Gynecol 21(1):39–43CrossRefPubMed

Dollner R, Granzow C, Werner JA, Dietz A (2004) Is there a role for chemosensitivity tests in head and neck cancer? Onkologie 27(3):310–315CrossRefPubMed

Fruehauf JP (2002) In vitro assay-assisted treatment selection for women with breast or ovarian cancer. Endocr Relat Cancer 9(3):171–182CrossRefPubMed

Gazdar AF, Steinberg SM, Russell EK, Linnoila RI, Oie HK, Ghosh BC, Cotelingam JD, Johnson BE, Minna JD, Ihde DC (1990) Correlation of in vitro drug-sensitivity testing results with response to chemotherapy and survival in extensive-stage small cell lung cancer: a prospective clinical trial. J Natl Cancer Inst 82(2):117–124CrossRefPubMed

Schrag D, Garewal HS, Burstein HJ, Samson DJ, Von Hoff DD, ASCO Somerfield MR Working Group on Chemotherapy Sensitivity Resistance Assays (2004) American Society of Clinical Oncology Technology Assessment: chemotherapy sensitivity and resistance assays. J Clin Oncol 22(17):3631–3638CrossRefPubMed

Title: Response evaluation in head and neck oncology
Authors: Robert Mandic
Jochen A. Werner
Publication date: 01-04-2010
Publisher: Springer-Verlag
Published in: European Archives of Oto-Rhino-Laryngology / Issue 4/2010
Print ISSN: 0937-4477
Electronic ISSN: 1434-4726
DOI: https://doi.org/10.1007/s00405-009-1192-4

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