Skip to main content
Top
Published in: European Archives of Oto-Rhino-Laryngology 10/2008

01-10-2008 | Rhinology

Novel treatment of atrophic rhinitis: early results

Authors: Abhishek Jaswal, Avik Kumar Jana, Biswajit Sikder, Tapan K. Nandi, Sanjoy Kumar Sadhukhan, Anjan Das

Published in: European Archives of Oto-Rhino-Laryngology | Issue 10/2008

Login to get access

Abstract

The aim of this randomized control trial, performed at a tertiary referral hospital, was to compare the therapeutic effectiveness of two novel treatment modalities, oral rifampicin and submucosal placentrex injection, in randomly selected patients of primary atrophic rhinitis regarding objective, subjective and histopathological improvement. Patients treated with oral rifampicin showed most promising results regarding objective, subjective and histopathological improvement with maximum disease-free interval on regular follow-up as compared to submucosal placentrex injections.
Literature
1.
go back to reference Sinha SM, Sardana DS, Rajvanshi VS (1977) A nine year review of 273 cases of atrophic rhinitis and its management. J Laryngol Otol 91:591–600PubMedCrossRef Sinha SM, Sardana DS, Rajvanshi VS (1977) A nine year review of 273 cases of atrophic rhinitis and its management. J Laryngol Otol 91:591–600PubMedCrossRef
2.
go back to reference Zohar Y, Talmi YP, Strauss M et al (1990) Ozaena revisited. J Otolaryngol 19:345–349PubMed Zohar Y, Talmi YP, Strauss M et al (1990) Ozaena revisited. J Otolaryngol 19:345–349PubMed
3.
go back to reference Dutta SN, Kameshwaran M (2005) The aetiology and management of atrophic rhinitis. J Laryngol Otol 119:843–852 Dutta SN, Kameshwaran M (2005) The aetiology and management of atrophic rhinitis. J Laryngol Otol 119:843–852
4.
go back to reference Moore EJ, Kern EB (2001) Atophic rhinitis: a review of 242 cases. Am J Rhinol 15:355–361PubMed Moore EJ, Kern EB (2001) Atophic rhinitis: a review of 242 cases. Am J Rhinol 15:355–361PubMed
5.
go back to reference Sen HC (1982) The ozaena problem, clinical analysis of atrophic rhinitis in 100 cases. Acta Otolaryngol 93:461–464CrossRef Sen HC (1982) The ozaena problem, clinical analysis of atrophic rhinitis in 100 cases. Acta Otolaryngol 93:461–464CrossRef
6.
go back to reference Goodman WS, de Souza FM (1973) Atrophic rhinitis. Otolaryngol Clin North Am 6:773–782PubMed Goodman WS, de Souza FM (1973) Atrophic rhinitis. Otolaryngol Clin North Am 6:773–782PubMed
7.
go back to reference Henricksen SD, Gundersen WB (1959) The etiology of ozaena. APMIS 47:380 Henricksen SD, Gundersen WB (1959) The etiology of ozaena. APMIS 47:380
8.
go back to reference Singh I, Raizada RM, Chaturvedi VN et al (1994) Atrophic rhinitis: a bacteriological profile. Indian J Otolaryngol 3:154–155 Singh I, Raizada RM, Chaturvedi VN et al (1994) Atrophic rhinitis: a bacteriological profile. Indian J Otolaryngol 3:154–155
9.
go back to reference Qizilbash AAH, Daif M (1992) Atrophic rhinitis revisited. Pakistan J Otolaryngol 8:197–199 Qizilbash AAH, Daif M (1992) Atrophic rhinitis revisited. Pakistan J Otolaryngol 8:197–199
10.
go back to reference Brook I (2004) Microbiology and antimicrobial management of sinusitis. Otolaryngol Clin North Am 37:253–266PubMedCrossRef Brook I (2004) Microbiology and antimicrobial management of sinusitis. Otolaryngol Clin North Am 37:253–266PubMedCrossRef
11.
go back to reference Kuruvilla G, Albert RRA, Job A et al (2006) Pneumocephalus: a rare complication of nasal myiasis. Am J Otolaryngol 27(2):133–135PubMedCrossRef Kuruvilla G, Albert RRA, Job A et al (2006) Pneumocephalus: a rare complication of nasal myiasis. Am J Otolaryngol 27(2):133–135PubMedCrossRef
12.
go back to reference Fouad H, Afifi N, Fatt-hi A et al (1990) Altered cell mediated immunity in atrophic rhinitis. J Laryngol Otol 94:507–514 Fouad H, Afifi N, Fatt-hi A et al (1990) Altered cell mediated immunity in atrophic rhinitis. J Laryngol Otol 94:507–514
13.
go back to reference Chakraborty PD, Bhattacharyya D (2005) Isolation of fibronectin type III like peptide from human placental extract used as wound healer. J Chromatogr B Analyt Technol Biomed Life Sci 818(1):67–73PubMedCrossRef Chakraborty PD, Bhattacharyya D (2005) Isolation of fibronectin type III like peptide from human placental extract used as wound healer. J Chromatogr B Analyt Technol Biomed Life Sci 818(1):67–73PubMedCrossRef
14.
go back to reference Singh SM, Gupta SC, Samuel KC et al (1976) Placental extract therapy in atrophic rhinitis. Eye Ear Nose Throat Mon 55:56–61 Singh SM, Gupta SC, Samuel KC et al (1976) Placental extract therapy in atrophic rhinitis. Eye Ear Nose Throat Mon 55:56–61
15.
go back to reference Dudlev JP (1987) Atrophic rhinitis, antibiotic treatment. Am J Otolaryngol 8:387–390CrossRef Dudlev JP (1987) Atrophic rhinitis, antibiotic treatment. Am J Otolaryngol 8:387–390CrossRef
16.
go back to reference Nielsen BC, Olinder-Nielsen AM, Malmborg AS (1995) Successful treatment of ozeana with ciprofloxacin. Rhinology 33:57–60PubMed Nielsen BC, Olinder-Nielsen AM, Malmborg AS (1995) Successful treatment of ozeana with ciprofloxacin. Rhinology 33:57–60PubMed
17.
go back to reference Barbary AS, Yassin A, Fouad H et al (1970) Histopathological and histochemical studies on atrophic rhinitis. J Laryngol Otol 84:1103–1112CrossRef Barbary AS, Yassin A, Fouad H et al (1970) Histopathological and histochemical studies on atrophic rhinitis. J Laryngol Otol 84:1103–1112CrossRef
18.
go back to reference Taylor M, Young A (1961) Histological and histochemical studies on atrophic rhinitis. J Laryngol Otol 75:574–589PubMed Taylor M, Young A (1961) Histological and histochemical studies on atrophic rhinitis. J Laryngol Otol 75:574–589PubMed
19.
go back to reference Mehrotra R, Singhal J, Kawatra M et al (2005) Pre and post-treatment histopathological changes in atrophic rhinitis. Indian J Pathol Microbiol 48(3):310–313PubMed Mehrotra R, Singhal J, Kawatra M et al (2005) Pre and post-treatment histopathological changes in atrophic rhinitis. Indian J Pathol Microbiol 48(3):310–313PubMed
Metadata
Title
Novel treatment of atrophic rhinitis: early results
Authors
Abhishek Jaswal
Avik Kumar Jana
Biswajit Sikder
Tapan K. Nandi
Sanjoy Kumar Sadhukhan
Anjan Das
Publication date
01-10-2008
Publisher
Springer-Verlag
Published in
European Archives of Oto-Rhino-Laryngology / Issue 10/2008
Print ISSN: 0937-4477
Electronic ISSN: 1434-4726
DOI
https://doi.org/10.1007/s00405-008-0629-5

Other articles of this Issue 10/2008

European Archives of Oto-Rhino-Laryngology 10/2008 Go to the issue