Skip to main content
Top
Published in: European Archives of Oto-Rhino-Laryngology 1/2007

01-01-2007 | Head and Neck

Concurrent primary Hodgkin’s lymphoma and recurrent pleomorphic adenoma of the ipsilateral parotid gland

Report of a rare case

Authors: Argyrios Manganaris, Frida Patakiouta, Anastasia Kiziridou, Theodoros Manganaris

Published in: European Archives of Oto-Rhino-Laryngology | Issue 1/2007

Login to get access

Abstract

The synchronous occurrence of two histologically different and morphologically distinct tumours in a single parotid gland is an exceptionally rare and probably coincidental event. We have recently experienced such a case initially suspected of being a recurrent pleomorphic adenoma. Superficial parotidectomy, however, revealed two separate masses. Postoperative histopathological examination diagnosed the presence of a pleomorphic adenoma with a concurrent primary parotid gland Hodgkin’s lymphoma arising from an intraglandular lymph node. The management of this case is presented along with a brief review of the literature concerning the evaluation and management of this rare entity.
Literature
1.
go back to reference Curry JL, Petruzzelli GJ, McClatchey KD, Lingen MW (2002) Synchronous benign and malignant salivary gland tumors in ipsilateral glands: a report of two cases and a review of literature. Head Neck 24(3):301–306PubMedCrossRef Curry JL, Petruzzelli GJ, McClatchey KD, Lingen MW (2002) Synchronous benign and malignant salivary gland tumors in ipsilateral glands: a report of two cases and a review of literature. Head Neck 24(3):301–306PubMedCrossRef
2.
go back to reference Batsakis JG (1979) Tumor of the head and neck, 2nd ed. Williams Wilkins, Baltimore, pp 2–75 Batsakis JG (1979) Tumor of the head and neck, 2nd ed. Williams Wilkins, Baltimore, pp 2–75
3.
go back to reference Nagata M, Kumazawa H, Iwai H, Momotani A, Shiraishi S, Yamashita T (1996) Study of malignant lymphoma in the parotid gland region. Nippon Jibiinkouka Gakkai Kaiho 99:918–25 Nagata M, Kumazawa H, Iwai H, Momotani A, Shiraishi S, Yamashita T (1996) Study of malignant lymphoma in the parotid gland region. Nippon Jibiinkouka Gakkai Kaiho 99:918–25
4.
5.
go back to reference Mehle ME, Kraus DH, Wood BG, Tubbs R, Tucker HM, Lavertu P (1993) Lymphoma of the parotid gland. Laryngoscope 103:17–21PubMedCrossRef Mehle ME, Kraus DH, Wood BG, Tubbs R, Tucker HM, Lavertu P (1993) Lymphoma of the parotid gland. Laryngoscope 103:17–21PubMedCrossRef
6.
go back to reference Dunn P, Kuo T, Shih LY, Lin TL, Wang PN, Kuo MC, Tang CC (2004) Primary salivary gland lymphoma: a clinicopathologic study of 23 cases in Taiwan. Acta Haematol 112:203–208PubMedCrossRef Dunn P, Kuo T, Shih LY, Lin TL, Wang PN, Kuo MC, Tang CC (2004) Primary salivary gland lymphoma: a clinicopathologic study of 23 cases in Taiwan. Acta Haematol 112:203–208PubMedCrossRef
7.
go back to reference Stewart A, Blenkinsopp TP, Henry K (1994) Bilatral parotid MALT lymphoma and Sjögren’s syndrome. Br J Oral Maxillofac Surg 32:318–322PubMedCrossRef Stewart A, Blenkinsopp TP, Henry K (1994) Bilatral parotid MALT lymphoma and Sjögren’s syndrome. Br J Oral Maxillofac Surg 32:318–322PubMedCrossRef
8.
go back to reference Royer B, Cazals-Hatem D, Sibilia J, Agbalika F, Cayuela JM, Soussi T, Maloisel F, Clauvel JP, Brouet JC, Mariette X (1997) Lymphomas in patients with Sjoegren’s sydrome are marginal zone B-cell neoplasms, arise in diverse extranodaland nodal sites, and are not associated with viruses. Blood 90:766–775PubMed Royer B, Cazals-Hatem D, Sibilia J, Agbalika F, Cayuela JM, Soussi T, Maloisel F, Clauvel JP, Brouet JC, Mariette X (1997) Lymphomas in patients with Sjoegren’s sydrome are marginal zone B-cell neoplasms, arise in diverse extranodaland nodal sites, and are not associated with viruses. Blood 90:766–775PubMed
9.
go back to reference Barnes L, Myers EN, Prokopakis EP (1998) Primary malignant lymphoma of the parotid gland. Arch Otolaryngol Head Neck Surg 124:573–577PubMed Barnes L, Myers EN, Prokopakis EP (1998) Primary malignant lymphoma of the parotid gland. Arch Otolaryngol Head Neck Surg 124:573–577PubMed
10.
go back to reference Sharkey FE (1977) Systemic evaluation of the World Health Organization classification of salivary gland tumors: a clinicopathologic study of 366 cases. Am J Clin Pathol 67:272–278PubMed Sharkey FE (1977) Systemic evaluation of the World Health Organization classification of salivary gland tumors: a clinicopathologic study of 366 cases. Am J Clin Pathol 67:272–278PubMed
11.
go back to reference Schusterman MA, Granick MS, Erickson ER, Newton D, Hanna DC, Brighten R (1988) Lymphomas presenting as a salivary gland mass. Head Neck Surg 10:411–415 PubMedCrossRef Schusterman MA, Granick MS, Erickson ER, Newton D, Hanna DC, Brighten R (1988) Lymphomas presenting as a salivary gland mass. Head Neck Surg 10:411–415 PubMedCrossRef
12.
go back to reference Bears OH, Woolner LB, Carveth SW, Devine KD (1960) Surgical management of parotid lesions: a review of 760 cases. Arch Surg 80:890–904 Bears OH, Woolner LB, Carveth SW, Devine KD (1960) Surgical management of parotid lesions: a review of 760 cases. Arch Surg 80:890–904
13.
go back to reference Patey DH (1965) Malignant disease of the parotid gland. Br J Cancer 19:712–737PubMed Patey DH (1965) Malignant disease of the parotid gland. Br J Cancer 19:712–737PubMed
14.
15.
go back to reference Watkin GT, MacLennan KA, Hobsley M (1984) Lymphomas presenting as lumps in the parotid region. Br J Surg 71:701–702PubMedCrossRef Watkin GT, MacLennan KA, Hobsley M (1984) Lymphomas presenting as lumps in the parotid region. Br J Surg 71:701–702PubMedCrossRef
16.
go back to reference Sarris AH, Papadimitrakopoulou V, Dimopoulos MA, Smith T, Pugh W, Ha GS, McLaughlin P, Callender D, Cox J, Cabanillas F (1997) Primary parotid lymphoma: the effect of International Prognostic Index on outcome. Leuk Lymphoma 26:49–56PubMed Sarris AH, Papadimitrakopoulou V, Dimopoulos MA, Smith T, Pugh W, Ha GS, McLaughlin P, Callender D, Cox J, Cabanillas F (1997) Primary parotid lymphoma: the effect of International Prognostic Index on outcome. Leuk Lymphoma 26:49–56PubMed
17.
go back to reference Schmid U, Helbron D, Lennert K (1982) Primary malignant lymphomas localized in salivary glands. Histopathology 6:673–687PubMedCrossRef Schmid U, Helbron D, Lennert K (1982) Primary malignant lymphomas localized in salivary glands. Histopathology 6:673–687PubMedCrossRef
18.
go back to reference Sciubba JJ, Auclair PL, Ellis GL (1991) Malignant lymphomas. In: Ellis GL, Auclair PL, Gnepp DR (eds) Surgical pathology of the salivary glands. Saunders, Philadelphia, pp 528–543 Sciubba JJ, Auclair PL, Ellis GL (1991) Malignant lymphomas. In: Ellis GL, Auclair PL, Gnepp DR (eds) Surgical pathology of the salivary glands. Saunders, Philadelphia, pp 528–543
19.
go back to reference Chan JKC, Tsang WYW, Hui PK, Sin VC, Siu LLP (1997) T- and T/natural killer-cell lymphomas of the salivary gland: a clinicopathologic, immunohistochemical and molecular study of six cases. Hum Pathol 28:238–245PubMedCrossRef Chan JKC, Tsang WYW, Hui PK, Sin VC, Siu LLP (1997) T- and T/natural killer-cell lymphomas of the salivary gland: a clinicopathologic, immunohistochemical and molecular study of six cases. Hum Pathol 28:238–245PubMedCrossRef
20.
go back to reference Harris NL (1991) Extra-nodal lymphoid infiltrates and mucosa-associated lymphoid tissue (MALT). Am J Surg Pathol 15:879–884PubMedCrossRef Harris NL (1991) Extra-nodal lymphoid infiltrates and mucosa-associated lymphoid tissue (MALT). Am J Surg Pathol 15:879–884PubMedCrossRef
21.
go back to reference Freling NJM, Molenaar WM, Vermey A, Mooyaart EL, Panders AK, Annyas AA, et al (1992) Malignant parotid tumors: clinical use of MR imaging and histologic correlation. Radiology 185:691–6PubMed Freling NJM, Molenaar WM, Vermey A, Mooyaart EL, Panders AK, Annyas AA, et al (1992) Malignant parotid tumors: clinical use of MR imaging and histologic correlation. Radiology 185:691–6PubMed
22.
go back to reference Hashida I, Tamaki Y, Sakurai H, Takahashi T, Maebayashi K, Hayakawa K, et al (1995) Malignant lymphoma of the parotid gland: a study of six cases. Gann no Rynsho 41:863–7 Hashida I, Tamaki Y, Sakurai H, Takahashi T, Maebayashi K, Hayakawa K, et al (1995) Malignant lymphoma of the parotid gland: a study of six cases. Gann no Rynsho 41:863–7
23.
go back to reference Hyman GA, Wolff M (1976) Malignant lymphoma of the salivary glands. Am J Clin Pathol 65:421–38PubMed Hyman GA, Wolff M (1976) Malignant lymphoma of the salivary glands. Am J Clin Pathol 65:421–38PubMed
24.
go back to reference Yencha MW (2002) Primary parotid gland Hodgkin’s lymphoma. Ann Otol Rhinol Laryngol 111(4):338–42PubMed Yencha MW (2002) Primary parotid gland Hodgkin’s lymphoma. Ann Otol Rhinol Laryngol 111(4):338–42PubMed
25.
go back to reference Hirokawa N, Hareyama M, Akiba H, Satoh M, Oouchi A, Tamakawa M, Sakata K, Nagakura H, Koito K, Morita K, Harabuchi Y, Kataura A, Hinoda Y (1998) Diagnosis and treatment of malignant lymphoma of the parotid gland. Jpn J Clin Oncol 28(4):245–9PubMedCrossRef Hirokawa N, Hareyama M, Akiba H, Satoh M, Oouchi A, Tamakawa M, Sakata K, Nagakura H, Koito K, Morita K, Harabuchi Y, Kataura A, Hinoda Y (1998) Diagnosis and treatment of malignant lymphoma of the parotid gland. Jpn J Clin Oncol 28(4):245–9PubMedCrossRef
26.
go back to reference Loggins JP, Urquhart A (2004) Preoperative distinction of parotid lymphomas. J Am Coll Surg 199(1):58–61PubMedCrossRef Loggins JP, Urquhart A (2004) Preoperative distinction of parotid lymphomas. J Am Coll Surg 199(1):58–61PubMedCrossRef
Metadata
Title
Concurrent primary Hodgkin’s lymphoma and recurrent pleomorphic adenoma of the ipsilateral parotid gland
Report of a rare case
Authors
Argyrios Manganaris
Frida Patakiouta
Anastasia Kiziridou
Theodoros Manganaris
Publication date
01-01-2007
Publisher
Springer-Verlag
Published in
European Archives of Oto-Rhino-Laryngology / Issue 1/2007
Print ISSN: 0937-4477
Electronic ISSN: 1434-4726
DOI
https://doi.org/10.1007/s00405-006-0132-9

Other articles of this Issue 1/2007

European Archives of Oto-Rhino-Laryngology 1/2007 Go to the issue