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01-08-2019 | Maternal-Fetal Medicine

Association of trimester-specific gestational weight gain with birth weight and fetal growth in a large community-based population

Authors: Yafei Mao, Shuojia Wang, Minchao Li, Manxian Huang, Minjia Mo, Leijun Gu, Xiamusiye Muyiduli, Hongyu Lian, Shuying Jiang, Zhaopin Wang, Bule Shao, Liuyan Pu, Yunxian Yu

Published in: Archives of Gynecology and Obstetrics | Issue 2/2019

Abstract

Background

Previous studies showed that the association of gestational weight gain (GWG) with fetal birthweight and offspring developmental growth was unclear. The aim of this study is to investigate the respective effect of 1 kg of GWG during three trimesters on birthweight and offspring growth from birth to 3 years of age.

Methods

We extracted the decoded information from the Maternal and Child Health Information Management System of Zhoushan Maternal and Child Health Hospital in Zhejiang, China from October 2001 to March 2015, and used multiple linear and logistic regression models.

Results

This study included 20,232 women with a full-term singleton birth and 15,557 newborns who took regular health check-ups. Compared to that in the 2nd and 3rd trimester, 1 kg GWG increasing in the 1st trimester had the strongest positive association with higher birthweight, body weight, and height from 1 to 36 months. Their associations with BMI after birth were similar among the three trimesters. In addition, some positive dose–response effects found between quartiles of GWG in the 1st trimester and offspring body weight, as well as BMI. The 1 kg GWG in 1st trimester played the strongest role in contributing to birth weight and benefiting to body growth among children aged up to 3 years.

Conclusion

The 1 kg GWG in 1st trimester contributed more to birth weight and body development from birth to 3 years compared to the 2nd and 3rd trimesters. The possible beneficial effects of GWG in the 1st trimester on birthweight and offspring development in under/normal weight mothers are found.

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Zhang CH, Liu XY, Zhan YW, Zhang L, Huang YJ, Zhou H (2015) Effects of prepregnancy body mass index and gestational weight gain on pregnancy outcomes. Asia Pac J Public Health 27(6):620–630CrossRef

Hill B, Skouteris H, McCabe M, Fuller-Tyszkiewicz M (2013) Body image and gestational weight gain: a prospective study. J Midwifery Women’s Health 58(2):189–194CrossRef

Bodnar LM, Hutcheon JA, Platt RW, Himes KP, Simhan HN, Abrams B (2011) Should gestational weight gain recommendations be tailored by maternal characteristics? Am J Epidemiol 174(2):136–146CrossRef

Wrotniak BH, Shults J, Butts S, Stettler N (2008) Gestational weight gain and risk of overweight in the offspring at age 7 y in a multicenter, multiethnic cohort study. Am J Clin Nutr 87(6):1818–1824CrossRef

Pregnancy Weight Gain During (2009) Reexamining the guidelines. National Academy of Sciences, Washington DC

Fortner RT, Pekow P, Solomon CG, Markenson G, Chasan-Taber L (2009) Prepregnancy body mass index, gestational weight gain, and risk of hypertensive pregnancy among Latina women. Am J Obstet Gynecol. 200(2):167 e1–7CrossRef

Carreno CA, Clifton RG, Hauth JC et al (2012) Excessive early gestational weight gain and risk of gestational diabetes mellitus in nulliparous women. Obstet Gynecol 119(6):1227–1233CrossRef

Li N, Liu E, Guo J et al (2013) Maternal prepregnancy body mass index and gestational weight gain on pregnancy outcomes. PLoS One 8(12):e82310CrossRef

Woolfolk CL, Harper LM, Flick L, Mathews K, Chang JJ (2016) Gestational weight gain and preterm birth: disparities in adolescent pregnancies. J Perinatol 36(12):1055–1060CrossRef

10.

Han Z, Lutsiv O, Mulla S, Rosen A, Beyene J, McDonald SD (2011) Low gestational weight gain and the risk of preterm birth and low birthweight: a systematic review and meta-analyses. Acta Obstet Gynecol Scand 90(9):935–954CrossRef

11.

Villar J, Puglia FA, Fenton TR et al (2017) Body composition at birth and its relationship with neonatal anthropometric ratios: the newborn body composition study of the INTERGROWTH-21(st) project. Pediatr Res 82(2):305–316CrossRef

12.

Lof M, Hilakivi-Clarke L, Sandin S, Weiderpass E (2008) Effects of pre-pregnancy physical activity and maternal BMI on gestational weight gain and birth weight. Acta Obstet Gynecol Scand 87(5):524–530CrossRef

13.

Ludwig DS, Currie J (2010) The association between pregnancy weight gain and birthweight: a within-family comparison. Lancet 376(9745):984–990CrossRef

14.

Margerison-Zilko CE, Shrimali BP, Eskenazi B, Lahiff M, Lindquist AR, Abrams BF (2012) Trimester of maternal gestational weight gain and offspring body weight at birth and age five. Matern Child Health J 16(6):1215–1223CrossRef

15.

Brown JE, Murtaugh MA, Jacobs DR Jr, Margellos HC (2002) Variation in newborn size according to pregnancy weight change by trimester. Am J Clin Nutr 76(1):205–209CrossRef

16.

Lantz ME, Chez RA, Rodriguez A, Porter KB (1996) Maternal weight gain patterns and birth weight outcome in twin gestation. Obstet Gynecol 87(4):551–556CrossRef

17.

Andersen CS, Gamborg M, Sorensen TI, Nohr EA (2011) Weight gain in different periods of pregnancy and offspring’s body mass index at 7 years of age. Int J Pediatric Obesity 6(2–2):e179–e186CrossRef

18.

Lampl M, Gotsch F, Kusanovic JP et al (2010) Sex differences in fetal growth responses to maternal height and weight. Am J Human Biol 22(4):431–443CrossRef

19.

Chen C, Lu FC (2004) The guidelines for prevention and control of overweight and obesity in Chinese adults. Biomed Environ Sci 17(Suppl):1–36PubMed

20.

Chinese Children Development Norm under the age of 7. http://www.nhfpc.gov.cn/zwgk/wtwj/201304/b64543eaaee1463992e8ce97441c59bb.shtml

21.

Liu X, Du J, Wang G, Chen Z, Wang W, Xi Q (2011) Effect of pre-pregnancy body mass index on adverse pregnancy outcome in north of China. Arch Gynecol Obstet 283(1):65–70CrossRef

22.

Alberico S, Montico M, Barresi V et al (2014) The role of gestational diabetes, pre-pregnancy body mass index and gestational weight gain on the risk of newborn macrosomia: results from a prospective multicentre study. BMC Pregnancy Childbirth 14:23CrossRef

23.

Savitz DA, Stein CR, Siega-Riz AM, Herring AH (2011) Gestational weight gain and birth outcome in relation to prepregnancy body mass index and ethnicity. Ann Epidemiol 21(2):78–85CrossRef

24.

Baugh N, Harris DE, Aboueissa AM, Sarton C, Lichter E (2016) The impact of maternal obesity and excessive gestational weight gain on maternal and infant outcomes in Maine: analysis of pregnancy risk assessment monitoring system results from 2000 to 2010. J Pregnancy 2016:5871313CrossRef

25.

Xu Z, Wen Z, Zhou Y, Li D, Luo Z (2017) Inadequate weight gain in obese women and the risk of small for gestational age (SGA): a systematic review and meta-analysis. J Matern Fetal Neonatal Med 30(3):357–367CrossRef

26.

Shinohara S, Uchida Y, Hirai M, Hirata S, Suzuki K (2016) Relationship between maternal hypoglycaemia and small-for-gestational-age infants according to maternal weight status: a retrospective cohort study in two hospitals. BMJ Open 6(12):e013749CrossRef

27.

Wander PL, Sitlani CM, Badon SE, Siscovick DS, Williams MA, Enquobahrie DA (2015) Associations of early and late gestational weight gain with infant birth size. Matern Child Health J 19(11):2462–2469CrossRef

28.

Sekiya N, Anai T, Matsubara M, Miyazaki F (2007) Maternal weight gain rate in the second trimester are associated with birth weight and length of gestation. Gynecol Obstet Invest 63(1):45–48CrossRef

29.

Rauff EL, Downs DS (2011) Mediating effects of body image satisfaction on exercise behavior, depressive symptoms, and gestational weight gain in pregnancy. Ann Behav Med 42(3):381–390CrossRef

30.

Thame M, Osmond C, Bennett F, Wilks R, Forrester T (2004) Fetal growth is directly related to maternal anthropometry and placental volume. Eur J Clin Nutr 58(6):894–900CrossRef

31.

Lawlor DA (2013) The Society for Social Medicine John Pemberton Lecture 2011. Developmental overnutrition–an old hypothesis with new importance? Int J Epidemiol. 42(1):7–29CrossRef

32.

Lawlor DA, Relton C, Sattar N, Nelson SM (2012) Maternal adiposity–a determinant of perinatal and offspring outcomes? Nat Rev Endocrinol 8(11):679–688CrossRef

33.

Yang QY, Liang JF, Rogers CJ, Zhao JX, Zhu MJ, Du M (2013) Maternal obesity induces epigenetic modifications to facilitate Zfp423 expression and enhance adipogenic differentiation in fetal mice. Diabetes 62(11):3727–3735CrossRef

34.

Morales E, Groom A, Lawlor DA, Relton CL (2014) DNA methylation signatures in cord blood associated with maternal gestational weight gain: results from the ALSPAC cohort. BMC Res Notes 7:278CrossRef

35.

Li C, Liu Y, Zhang W (2015) Joint and independent associations of gestational weight gain and pre-pregnancy body mass index with outcomes of pregnancy in Chinese Women: a retrospective cohort study. PLoS One 10(8):e0136850CrossRef

Title: Association of trimester-specific gestational weight gain with birth weight and fetal growth in a large community-based population
Authors: Yafei Mao
Shuojia Wang
Minchao Li
Manxian Huang
Minjia Mo
Leijun Gu
Xiamusiye Muyiduli
Hongyu Lian
Shuying Jiang
Zhaopin Wang
Bule Shao
Liuyan Pu
Yunxian Yu
Publication date: 01-08-2019
Publisher: Springer Berlin Heidelberg
Published in: Archives of Gynecology and Obstetrics / Issue 2/2019
Print ISSN: 0932-0067
Electronic ISSN: 1432-0711
DOI: https://doi.org/10.1007/s00404-019-05188-8

At a glance: The ONWARDS insulin icodec trials

Springer Medicine

Association of trimester-specific gestational weight gain with birth weight and fetal growth in a large community-based population

Abstract

Background

Methods

Results

Conclusion

At a glance: The ONWARDS insulin icodec trials

Springer Medicine

Abstract

Background

Methods

Results

Conclusion

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