Top

Archives of Gynecology and Obstetrics

Published in:

01-07-2018 | Review

Intrauterine HPV transmission: a systematic review of the literature

Authors: Andreas Zouridis, Theodoros Kalampokas, Konstantinos Panoulis, Nicolaos Salakos, Efthimios Deligeoroglou

Published in: Archives of Gynecology and Obstetrics | Issue 1/2018

Abstract

Purpose

To evaluate the percentage of intrauterine vertical human papillomavirus (HPV) transmission among HPV-positive mothers and the relative risk of intrauterine vertical HPV transmission between cesarean and vaginal delivery among HPV-positive women.

Methods

This systematic review was made according to the PRISMA statement. We searched PubMed and Scopus and the final articles were selected by two reviewers. Data from the selected articles were plotted, and the pooled percentage of antenatal vertical HPV transmission among HPV-positive mothers as well as the pooled relative risk of antenatal vertical HPV transmission between cesarean and vaginal delivery among HPV-positive women were calculated.

Results

9 studies including 421 HPV-positive mothers and their offsprings were selected from 434 potential papers. Following meta-analysis, the pooled percentage of antenatal vertical HPV transmission was 4.936% (95% CI 1.651–9.849), with moderate heterogeneity between the studies (I² = 72.22%). The pooled relative risk of antenatal vertical HPV transmission between cesarean and vaginal delivery among HPV-positive women was 0.912, with no statistical significance (95% CI 0.226–3.674) and homogeneity between the studies (I² = 24.48%).

Syrjänen S (2010) Current concepts on human papillomavirus infections in children. APMIS 118(6–7):494–509CrossRef

Sonnex C, Strauss S, Gray JJ (1999) Detection of human papillomavirus DNA on the fingers of patients with genital warts. Sex Transm Infect 75(5):317–319CrossRef

Winer RL, Hughes JP, Feng Q, Xi LF, Cherne S, O’Reilly S, Kiviat NB, Koutsky LA (2010) Detection of genital HPV types in fingertip samples from newly sexually active female university students. Cancer Epidemiol Biomarkers Prev 19(7):1682–1685CrossRef

Bodaghi S, Wood LV, Roby G, Ryder C, Steinberg SM, Zheng ZM (2005) Could human papillomaviruses be spread through blood? J Clin Microbiol 43(11):5428–5434CrossRef

Lacour DE, Trimble C (2012) Human papillomavirus in infants: transmission, prevalence, and persistence. J Pediatr Adolesc Gynecol 25(2):93–97CrossRef

Medeiros LR, Ethur AB, Hilgert JB, Zanini RR, Berwanger O, Bozzetti MC, Mylius LC (2005) Vertical transmission of the human papillomavirus: a systematic quantitative review. Cad Saude Publica 21(4):1006–1015CrossRef

Chatzistamatiou K, Sotiriadis A, Agorastos T (2016) Effect of mode of delivery on vertical human papillomavirus transmission—a meta-analysis. J Obstet Gynaecol 36(1):10–14CrossRef

Freitas AC, Mariz FC, Silva MA, Jesus AL (2013) Human papillomavirus vertical transmission: review of current data. Clin Infect Dis 56(10):1451–1456CrossRef

Armbruster-Moraes E, Ioshimoto LM, Leão E, Zugaib M (1994) Presence of human papillomavirus DNA in amniotic fluids of pregnant women with cervical lesions. Gynecol Oncol 54(2):152–158CrossRef

10.

Uribarren-Berrueta O, Sánchez-Corona J, Montoya-Fuentes H, Trujillo-Hernández B, Vásquez C (2012) Presence of HPV DNA in placenta and cervix of pregnant Mexican women. Arch Gynecol Obstet 285(1):55–60CrossRef

11.

Wang X, Zhu Q, Rao H (1998) Maternal–fetal transmission of human papillomavirus. Chin Med J (Engl) 111(8):726–727

12.

Pao CC, Lin SS, Lin CY, Maa JS, Lai CH, Hsieh TT (1991) Identification of human papillomavirus DNA sequences in peripheral blood mononuclear cells. Am J Clin Pathol 95(4):540–546CrossRef

13.

Younes AS, Csire M, Kapusinszky B, Szomor K, Takács M, Berencsi G (2009) Heterogeneous pathways of maternal–fetal transmission of human viruses (review). Pathol Oncol Res 15(3):451–465CrossRef

14.

Moher D, Liberati A, Tetzlaff J, Altman DG, PRISMA Group (2010) Preferred reporting items for systematic reviews and meta-analyses: the PRISMA statement. Int J Surg 8(5):336–341CrossRef

15.

Sánchez-Torices MS, Corrales-Millan R, Hijona-Elosegui JJ (2016) Oropharyngeal perinatal colonization by human papillomavirus. Acta Otorrinolaringol Esp 67(3):135–141CrossRef

16.

Lee SM, Park JS, Norwitz ER, Koo JN, Oh IH, Park JW, Kim SM, Kim YH, Park CW, Song YS (2013) Risk of vertical transmission of human papillomavirus throughout pregnancy: a prospective study. PLoS ONE 8(6):e66368CrossRef

17.

Skoczyński M, Goździcka-Józefiak A, Kwaśniewska A (2014) Risk factors of the vertical transmission of human papilloma virus in newborns from singleton pregnancy—preliminary report. J Matern Fetal Neonatal Med 27(3):239–242CrossRef

18.

Hahn HS, Kee MK, Kim HJ, Kim MY, Kang YS, Park JS, Kim TJ (2013) Distribution of maternal and infant human papillomavirus: risk factors associated with vertical transmission. Eur J Obstet Gynecol Reprod Biol 169(2):202–206CrossRef

19.

Rombaldi RL, Serafini EP, Mandelli J, Zimmermann E, Losquiavo KP (2008) Transplacental transmission of human papillomavirus. Virol J 25(5):106CrossRef

20.

Gajewska M, Marianowski L, Wielgos M, Malejczyk M, Majewski S (2005) The occurrence of genital types of human papillomavirus in normal pregnancy and in pregnant women with pregestational insulin dependent diabetes mellitus. Neuro Endocrinol Lett 26(6):766–770PubMed

21.

Worda C, Huber A, Hudelist G, Schatten C, Leipold H, Czerwenka K, Eppel W (2005) Prevalence of cervical and intrauterine human papillomavirus infection in the third trimester in asymptomatic women. J Soc Gynecol Investig 12(6):440–444CrossRef

22.

Tseng CJ, Lin CY, Wang RL, Chen LJ, Chang YL, Hsieh TT, Pao CC (1992) Possible transplacental transmission of human papillomaviruses. Am J Obstet Gynecol 166(1 Pt 1):35–40CrossRef

23.

Trottier H, Meyrand M, Coutlee F, Human Monnier P et al (2016) Papillomavirus (HPV) perinatal transmission and risk of HPV persistence among children: design, methods and preliminary results of the HERITAGE study. Papillomavirus Res 2:145–152CrossRef

24.

Watts DH, Koutsky LA, Holmes KK, Goldman D, Kuypers J, Kiviat NB, Galloway DA (1998) Low risk of perinatal transmission of human papillomavirus: results from a prospective cohort study. Am J Obstet Gynecol 178(2):365–373CrossRef

25.

Tseng CJ, Liang CC, Soong YK, Pao CC (1998) Perinatal transmission of human papillomavirus in infants: relationship between infection rate and mode of delivery. Obstet Gynecol 91(1):92–96CrossRef

Title: Intrauterine HPV transmission: a systematic review of the literature
Authors: Andreas Zouridis
Theodoros Kalampokas
Konstantinos Panoulis
Nicolaos Salakos
Efthimios Deligeoroglou
Publication date: 01-07-2018
Publisher: Springer Berlin Heidelberg
Published in: Archives of Gynecology and Obstetrics / Issue 1/2018
Print ISSN: 0932-0067
Electronic ISSN: 1432-0711
DOI: https://doi.org/10.1007/s00404-018-4787-4

At a glance: The ONWARDS insulin icodec trials

Springer Medicine

Intrauterine HPV transmission: a systematic review of the literature

Abstract

Purpose

Methods

Results

At a glance: The ONWARDS insulin icodec trials

Springer Medicine

Abstract

Purpose

Methods

Results

Please log in to get access to this content

Other articles of this Issue 1/2018

Liquid-based cytology: do ancillary techniques enhance detection of epithelial abnormalities?

Can a quality-of-life assessment assist in identifying women at risk of prematurely discontinuing IVF treatment? A prospective cohort study utilizing the FertiQoL questionnaire

Study on the effects of an oral lactobacilli and lactoferrin complex in women with intermediate vaginal microbiota

Cytological assessment of endometrial washings obtained with Karman cannula using a liquid-based preparation method for the detection of endometrial pathologies

What are the prevalence, characteristics and significance of fetal lateral neck cysts detected in an early anatomical scan?

Does tumor grade influence the rate of lymph node metastasis in apparent early stage ovarian cancer?