Top

Archives of Gynecology and Obstetrics

Published in:

01-03-2018 | Maternal-Fetal Medicine

Effects of dietary advice on insulin-like growth factors among healthy newborns

Authors: Emre Özgür Bulduk, Sıdıka Bulduk, Burcu Biral Coşkun

Published in: Archives of Gynecology and Obstetrics | Issue 3/2018

Abstract

Objectives

In fetal life, insulin, insulin-like growth factor (IGF) 1, IGF 2 and IGF-binding protein (IGFBP) 3 are essential growth factors. The purpose of this study is to investigate the effects of dietary intervention on insulin-like growth factors in the cord blood of neonates.

Methods

The study involved 52 pregnant women who were followed up in Gazi University Medical School Hospital at Ankara, Turkey. They were randomly divided into two groups: The experimental group was involved in nutrition education. We measured IGF 1, IGF 2 and IGFBP 3 concentrations in cord blood from 52 neonates.

Results

In the experimental group, cord serum levels of IGF 1, IGF 2 were observed to be higher than that of control group.

Conclusion

Dietary advice had positive effects on the cord serum IGF 1 and IGF 2 concentrations. Dietary advice during pregnancy proved to be effective in fetal development.

Available only for authorised users

Halje M, Nordin M, Bergman D, Engström W (2012) The effect of insulin-like growth factor II in the regulation of tumour cell growth in vitro and tumourigenesis in vivo. In Vivo 26(4):519–526PubMed

Livingstone C (2013) Insulin-like growth factor-I (IGF-I) and clinical nutrition. Clin Sci 125:265–280CrossRefPubMed

Clemmons DR (2009) Role of IGF-I in skeletal muscle mass maintenance. Trends Endocrinol Metab 20:349–356CrossRefPubMed

Wu X, Zhao H, Do KA, Johnson MM, Dong Q, Hong WK, Spitz MR (2004) Serum levels of insulin growth factor (IGF-I) and IGF-binding protein predict risk of second primary tumors in patients with head and neck cancer. Clin Cancer Res 10(12):3988–3995CrossRefPubMed

Abribat T, Nedelec B, Jobin N, Garrel DR (2000) Decreased serum insulin-like growth factor-I in burn patients: relationship with serum insulin-like growth factor binding protein-3 proteolysis and the influence of lipid composition in nutritional support. Crit Care Med 28:2366–2372CrossRefPubMed

Espelund U, Bruun JM, Richelsen B, Flyvbjerg A, Frystyk J (2005) Pro- and mature IGF-II during diet-induced weight loss in obese subjects. Eur J Endocrinol 153:861–869CrossRefPubMed

Nawathe AR, Christian M, Kim SH, Johnson M, Savvidou MD, Terzidou V (2016) Insulin-like growth factor axis in pregnancies affected by fetal growth disorders. Clin Epigenet 8(11):1–13

Ranke MB (2015) Insulin-like growth factor binding-protein-3. Best Pract Res Clin Endocrinol Metab 29:701–711CrossRefPubMed

Landmann E, Kollerits B, Kreuder JG, Blum WF, Kronenberg F, Rudloff S (2012) Influence of polymorphisms in genes encoding for insulin-like growth factor (IGF)-I, insulin, and IGF-binding protein (IGFBP)-3 on IGF-I, IGF-II, and IGFBP-3 levels in umbilical cord plasma. Horm Res Paediatr 77(6):341–350CrossRefPubMed

10.

Tzschoppe A, Riedel C, von Kries R, Struwe E, Rascher W, Dörr HG, Beckmann MW, Schild RL, Goecke TW, Flyvbjerg A, Frystyk J, Dötsch J (2015) Differential effects of low birthweight and intrauterine growth restriction on umbilical cord blood insulin-like growth factor concentrations. Clin Endocrinol (Oxf) 83(5):739–745CrossRef

11.

Lee SE, Talegawkar SA, Merialdi M, Caulfield LE (2013) Dietary intakes of women during pregnancy in low-and middle-income countries. Publ Health Nutr 16(08):1340–1353CrossRef

12.

Shamim AA, Mashreky SR, Ferdous T, Tegenfeldt K, Roy S, Rahman AK, Rashid I, Haque R, Rahman Z, Hossen K, Siddiquee SR, Rahman M, Sanghvi TG, Shaheen N (2016) Pregnant women diet quality and its sociodemographic determinants in Southwestern Bangladesh. Food Nutr Bull 37(1):14–26CrossRefPubMed

13.

Bookari K, Yeatman H, Williamson M (2016) Exploring Australian women’s level of nutrition knowledge during pregnancy: a cross-sectional study. Int J Women’s Health 8:405–419CrossRef

14.

Villanueva-Ortega E, Garcés-Hernández MJ, Garibay Nieto GN (2017) Pre- and post-natal nutritional factors in the metabolic regulation of obesity. Revista Médica del Hospital General de México 80(2):111–118CrossRef

15.

Soliman A, De Sanctis V, Elalaily R (2014) Nutrition and pubertal development. Indian J Endocrinol Metab 18(1):39–47CrossRef

16.

Borazjani F, Angali KA, Kulkarni SS (2013) Milk and protein intake by pregnant women affects growth of foetus. J Health Popul Nutr 31(4):435–445PubMedPubMedCentral

17.

Samur G (2008) Gebelik ve Emziklilik Döneminde Beslenme, Sağlık Bakanlığı Yayın No: 726, Ankara

18.

Ajantha AKS, Malhotra B, Mohan SK, Joshi A (2015) Evaluation of dietary choices, preferences, knowledge and related practices among pregnant women living in an indian setting. J Clin Diagn Res 9(8):4–10

19.

Shapiro ALB, Kaar JL, Crume TL, Starling AP, Siega-Riz AM, Ringham BM, Glueck DH, Norris JM, Barbour LA, Friedman JE, Dabelea D (2016) Maternal diet quality in pregnancy and neonatal adiposity: the Healthy Start Study. Int J Obes 40(7):1056–1062CrossRef

20.

Olausson H, Löf M, Brismar K, Forsum E, Sohlström A (2010) Maternal serum concentrations of insulin-like growth factor (IGF)-I and IGF binding protein-1 before and during pregnancy in relation to maternal body weight and composition and infant birth weight. Br J Nutr 104:842–848CrossRefPubMed

21.

Javaid M, Godfrey K, Taylor P, Shore S, Breier B, Arden N, Cooper C (2004) Umbilical venous IGF-1 concentration, neonatal bone mass, and body composition. J Bone Miner Res 19:56–63CrossRefPubMed

22.

Gohlke BC, Fahnenstich H, Dame C, Albers N (2004) Longitudinal data for intrauterine levels of fetal IGF-I and IGF-II. Horm Res 61(4):200–204PubMed

23.

Hung TY, Lin CC, Hwang YS, Lin SJ, Chou YY, Tsai WH (2008) Relationship between umbilical cord blood insulin-like growth factors and anthropometry in term newborns. Acta Paediatr Taiwan 49(1):19–23PubMed

24.

Smerieri A, Petraroli M, Ziveri MA, Volta C, Bernasconi S, Street ME (2011) Effects of cord serum insulin, IGF-II, IGFBP-2, IL-6 and cortisol concentrations on human birth weight and length: pilot study. PLoS One 6(12):1–4CrossRef

25.

Napoli F, Di Iorgi N, Bagnasco F, Cangemi G, D’Amico B, Boschetti M, Allegri AE, Bruzzone Ichim IA, Traggiai C, Allodi A, Polo Perucchin P, Ghezzi M, Noli S, Giaccardi M, Roviglione B, De Miglio L, Calcagno A, Lorini R, Maghnie M (2014) Growth factors and metabolic markers in cord blood: relationship to birth weight and length. J Biol Regul Homeost Agents 28(2):237–249PubMed

26.

Chiesa C, Osborn JF, Haass C, Natale F, Spinelli M, Scapillati E, Spinelli A, Pacifico L (2008) Ghrelin, leptin, IGF-1, IGFBP-3, and insulin concentrations at birth: is there a relationship with fetal growth and neonatal anthropometry? Clin Chem 54(3):550–558CrossRefPubMed

27.

Pathmaperuma AN, Tennekoon KH, Senanayake L, Karunanayake EH (2007) Maternal and cord blood levels of insulin-like growth factors–I and–II and insulin-like growth factor binding protein-1: correlation with birth weight and maternal anthropometric indices. Ceylon Med J 52(2):48–52CrossRefPubMed

28.

Haspolat K, Ece A, Gürkan F, Atamer Y, Tutanç M, Yolbaş I (2007) Relationships between leptin, insulin, IGF-1 and IGFBP-3 in children with energy malnutrition. Clin Biochem 40(3–4):201–205CrossRefPubMed

29.

Tseng YM, Hwang YS, Lu CL, Lin SJ, Tsai WH (2014) Association of umbilical cord plasma acid-labile subunit of the insulin-like growth factor ternary complex with anthropometry in term newborns. Pediatr Neonatol 55(2):139–144CrossRefPubMed

30.

Teng RJ, Wu TJ, Hsieh FJ (2015) Cord blood level of insulin-like growth factor-1 and IGF binding protein-3 in monochorionic twins. J Formos Med Assoc 114(4):359–362CrossRefPubMed

31.

Switkowski KM, Jacques PF, Must A, Hivert MF, Fleisch A, Gillman MW, Rifas-Shiman S, Oken E (2017) Higher maternal protein intake during pregnancy is associated with lower cord blood concentrations of insulin-like growth factor (IGF)-II, IGF binding protein 3, and insulin, but not IGF-I, in a cohort of women with high protein intake. J Nutr 7:1–9

32.

Karakaş S, Metin Tellioğlu A, Dişcigil G, Karul AB, Türkmen M (2015) Relationships between anthropometric measurements, leptin and IGF-1 levels in Turkish healthy newborns. J Clin Exp Investig 6(3):214–219

Title: Effects of dietary advice on insulin-like growth factors among healthy newborns
Authors: Emre Özgür Bulduk
Sıdıka Bulduk
Burcu Biral Coşkun
Publication date: 01-03-2018
Publisher: Springer Berlin Heidelberg
Published in: Archives of Gynecology and Obstetrics / Issue 3/2018
Print ISSN: 0932-0067
Electronic ISSN: 1432-0711
DOI: https://doi.org/10.1007/s00404-017-4645-9

At a glance: The STEP trials

Springer Medicine

Effects of dietary advice on insulin-like growth factors among healthy newborns

Abstract

Objectives

Methods

Results

Conclusion

At a glance: The STEP trials

Springer Medicine

Abstract

Objectives

Methods

Results

Conclusion

Please log in to get access to this content

Other articles of this Issue 3/2018

Membrane sweeping added to formal induction method to increase the spontaneous vaginal delivery: a meta-analysis

Letter to the Editor: Comment on “Contemporary epidemiology and novel predictors of uterine rupture: a nationwide population-based study”

Comment on “Contemporary epidemiology and novel predictors of uterine rupture: a nationwide population-based study”

Does she have adnexal torsion? Prediction of adnexal torsion in reproductive age women

Increased proportion of mature oocytes with sustained-release growth hormone treatment in poor responders: a prospective randomized controlled study

Risk of parametrial invasion in women with early stage cervical cancer: a meta-analysis