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Published in: Archives of Gynecology and Obstetrics 1/2017

01-07-2017 | Maternal-Fetal Medicine

Birth weight and its relation with medical nutrition therapy in gestational diabetes

Authors: Marianne Vestgaard, Allan Stubbe Christensen, Lone Viggers, Finn Friis Lauszus

Published in: Archives of Gynecology and Obstetrics | Issue 1/2017

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Abstract

Purpose

The cornerstone in treatment of gestational diabetes mellitus (GDM) is medical nutrition therapy (MNT), but the effect on birth weight is disputed. The birth weight was evaluated with respect to length of MNT and adherence to diet.

Methods

We performed a cohort study on 436 women with GDM and 254 non-diabetic women. Women with a normal oral glucose tolerance test were included as controls as they had similar background predisposition as the women with GDM. The GDM women were subdivided according to MNT and the nutritional status was further stratified according to adherence to the current dietary guidelines.

Results

Birth weight above 4 kg was more prevalent in the non-diabetic women compared to the diet-treated GDM women (27 vs. 18%, p = 0.012) but similar to the GDM women who had no MNT (24%). Lower birth weight was associated with longer duration of MNT (r = −0.13, p = 0.021). The birth weight was 1.2 g lower per day of treatment.

Conclusions

Medical nutrition therapy was associated with reduction of the fetal weight in women with GDM and the weight decreases with length of treatment. Birth weight above 4 kg was as prominent in the non-diabetic women as in the women with GDM without MNT.
Literature
5.
go back to reference Crowther CA, Hiller JE, Moss JR, McPhee AJ, Jeffries WS, Robinson JS et al (2005) Effect of treatment of gestational diabetes mellitus on pregnancy outcomes. New Engl J Med 352(24):2477–2486. doi:10.1056/NEJMoa042973 CrossRefPubMed Crowther CA, Hiller JE, Moss JR, McPhee AJ, Jeffries WS, Robinson JS et al (2005) Effect of treatment of gestational diabetes mellitus on pregnancy outcomes. New Engl J Med 352(24):2477–2486. doi:10.​1056/​NEJMoa042973 CrossRefPubMed
6.
go back to reference Hartling L, Dryden DM, Guthrie A, Muise M, Vandermeer B, Donovan L (2013) Benefits and harms of treating gestational diabetes mellitus: a systematic review and meta-analysis for the U.S. Preventive Services Task Force and the National Institutes of Health Office of Medical Applications of Research. Ann Intern Med 159(2):123–129. doi:10.7326/0003-4819-159-2-201307160-00661 CrossRefPubMed Hartling L, Dryden DM, Guthrie A, Muise M, Vandermeer B, Donovan L (2013) Benefits and harms of treating gestational diabetes mellitus: a systematic review and meta-analysis for the U.S. Preventive Services Task Force and the National Institutes of Health Office of Medical Applications of Research. Ann Intern Med 159(2):123–129. doi:10.​7326/​0003-4819-159-2-201307160-00661 CrossRefPubMed
11.
go back to reference Di Carlo C, Iannotti G, Sparice S, Chiacchio MP, Greco E, Tommaselli GA et al (2014) The role of a personalized dietary intervention in managing gestational weight gain: a prospective, controlled study in a low-risk antenatal population. Arch Gynecol Obstet 289:765. doi:10.1007/s00404-013-3054-y CrossRefPubMed Di Carlo C, Iannotti G, Sparice S, Chiacchio MP, Greco E, Tommaselli GA et al (2014) The role of a personalized dietary intervention in managing gestational weight gain: a prospective, controlled study in a low-risk antenatal population. Arch Gynecol Obstet 289:765. doi:10.​1007/​s00404-013-3054-y CrossRefPubMed
12.
go back to reference Deveer R, Deveer M, Akbaba E, Engin-Ustun Y, Aydogan P, Celikkaya H et al (2013) The effect of diet on pregnancy outcomes among pregnant with abnormal glucose challenge test. Eur Rev Med Pharm Sci 17(9):1258–1261 Deveer R, Deveer M, Akbaba E, Engin-Ustun Y, Aydogan P, Celikkaya H et al (2013) The effect of diet on pregnancy outcomes among pregnant with abnormal glucose challenge test. Eur Rev Med Pharm Sci 17(9):1258–1261
14.
go back to reference Viana LV, Gross JL, Azevedo MJ (2014) Dietary intervention in patients with gestational diabetes mellitus: a systematic review and meta-analysis of randomized clinical trials on maternal and newborn outcomes. Diabetes Care 37(12):3345–3355. doi:10.2337/dc14-1530 CrossRefPubMed Viana LV, Gross JL, Azevedo MJ (2014) Dietary intervention in patients with gestational diabetes mellitus: a systematic review and meta-analysis of randomized clinical trials on maternal and newborn outcomes. Diabetes Care 37(12):3345–3355. doi:10.​2337/​dc14-1530 CrossRefPubMed
17.
go back to reference Teramo KA, Hiilesmaa VK, Schwartz R, Clemons GK, Widness JA (2004) Amniotic fluid and cord plasma erythropoietin levels in pregnancies complicated by preeclampsia, pregnancy-induced hypertension and chronic hypertension. J Perinat Med 32(3):240–247. doi:10.1515/JPM.2004.045 CrossRefPubMed Teramo KA, Hiilesmaa VK, Schwartz R, Clemons GK, Widness JA (2004) Amniotic fluid and cord plasma erythropoietin levels in pregnancies complicated by preeclampsia, pregnancy-induced hypertension and chronic hypertension. J Perinat Med 32(3):240–247. doi:10.​1515/​JPM.​2004.​045 CrossRefPubMed
22.
go back to reference Moses RG, Luebcke M, Davis WS, Coleman KJ, Tapsell LC, Petocz P et al (2006) Effect of a low-glycemic-index diet during pregnancy on obstetric outcomes. Am J Clin Nutr 84(4):807–812PubMed Moses RG, Luebcke M, Davis WS, Coleman KJ, Tapsell LC, Petocz P et al (2006) Effect of a low-glycemic-index diet during pregnancy on obstetric outcomes. Am J Clin Nutr 84(4):807–812PubMed
24.
25.
go back to reference Jensen DM, Korsholm L, Ovesen P, Beck-Nielsen H, Mølsted-Pedersen L, Damm P (2008) Adverse pregnancy outcome in women with mild glucose intolerance: is there a clinically meaningful threshold value for glucose? Acta Obstet Gynecol Scand 87(1):59–62. doi:10.1080/00016340701823975 CrossRefPubMed Jensen DM, Korsholm L, Ovesen P, Beck-Nielsen H, Mølsted-Pedersen L, Damm P (2008) Adverse pregnancy outcome in women with mild glucose intolerance: is there a clinically meaningful threshold value for glucose? Acta Obstet Gynecol Scand 87(1):59–62. doi:10.​1080/​0001634070182397​5 CrossRefPubMed
26.
go back to reference Catalano PM, McIntyre HD, Cruickshank JK, McCance DR, Dyer AR, Metzger BE et al (2012) The hyperglycemia and adverse pregnancy outcome study: associations of GDM and obesity with pregnancy outcomes. Diabetes Care 35(4):780–786. doi:10.2337/dc11-1790 CrossRefPubMedPubMedCentral Catalano PM, McIntyre HD, Cruickshank JK, McCance DR, Dyer AR, Metzger BE et al (2012) The hyperglycemia and adverse pregnancy outcome study: associations of GDM and obesity with pregnancy outcomes. Diabetes Care 35(4):780–786. doi:10.​2337/​dc11-1790 CrossRefPubMedPubMedCentral
Metadata
Title
Birth weight and its relation with medical nutrition therapy in gestational diabetes
Authors
Marianne Vestgaard
Allan Stubbe Christensen
Lone Viggers
Finn Friis Lauszus
Publication date
01-07-2017
Publisher
Springer Berlin Heidelberg
Published in
Archives of Gynecology and Obstetrics / Issue 1/2017
Print ISSN: 0932-0067
Electronic ISSN: 1432-0711
DOI
https://doi.org/10.1007/s00404-017-4396-7

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