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01-01-2016 | General Gynecology

Biocompatible porcine dermis graft to treat severe cystocele: impact on quality of life and sexuality

Authors: Salvatore Giovanni Vitale, Salvatore Caruso, Agnese Maria Chiara Rapisarda, Gaetano Valenti, Diego Rossetti, Stefano Cianci, Antonio Cianci

Published in: Archives of Gynecology and Obstetrics | Issue 1/2016

Abstract

Purpose

To study the quality of life (QoL) and sexual function changes of women affected by severe cystocele treated using biocompatible porcine dermis graft.

Methods

20 women (ranging in age from 47 to 71 years, mean age 58.7) with third- and fourth-degree cystocele (according to Baden and Walker classification) were enrolled. The Short Form-36 questionnaire to assess QoL was administrated at baseline and 12 months after surgical treatment. The Pelvic Organ Prolapse/Urinary Incontinence Sexual Questionnaire (PISQ-12) to measure the changes of sexual behavior was used at baseline and 12 months after surgical treatment. Each woman underwent translabial color Doppler ultrasonography to measure the clitoral blood flow before and 12 months after surgical treatment.

Results

Women reported QoL improvement (P < 0.001). By PISQ-12, improvement of the behavioral emotive factor score, the physical factor score, the partner-related factor score and of the total score during the 12-month follow-up with respect to baseline experience was observed (P < 0.001). Color Doppler measurement showed that the mean pulsatility index, peak systolic velocity, resistance index and end-diastolic velocity of clitoral arteries did not significantly change (P = NS).

Conclusions

Biocompatible porcine dermis graft to treat severe cystocele considerably improves QoL and sexual function, and does not influence clitoral blood flow. Our data could add new information about sexual behavior after prolapse treatment using this kind of graft, particularly about the impact on clitoral blood flow changes.

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Title: Biocompatible porcine dermis graft to treat severe cystocele: impact on quality of life and sexuality
Authors: Salvatore Giovanni Vitale
Salvatore Caruso
Agnese Maria Chiara Rapisarda
Gaetano Valenti
Diego Rossetti
Stefano Cianci
Antonio Cianci
Publication date: 01-01-2016
Publisher: Springer Berlin Heidelberg
Published in: Archives of Gynecology and Obstetrics / Issue 1/2016
Print ISSN: 0932-0067
Electronic ISSN: 1432-0711
DOI: https://doi.org/10.1007/s00404-015-3820-0

At a glance: The STEP trials

Springer Medicine

Biocompatible porcine dermis graft to treat severe cystocele: impact on quality of life and sexuality

Abstract

Purpose

Methods

Results

Conclusions

At a glance: The STEP trials

Springer Medicine

Abstract

Purpose

Methods

Results

Conclusions

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