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01-08-2015 | Maternal-Fetal Medicine

Renal oligo- and anhydramnios: cause, course and outcome—a single-center study

Authors: Judith Eva Spiro, Martin Konrad, Esther Rieger-Fackeldey, Katja Masjosthusmann, Susanne Amler, Walter Klockenbusch, Ralf Schmitz

Published in: Archives of Gynecology and Obstetrics | Issue 2/2015

Abstract

Purpose

To evaluate the outcome of patients with renal oligohydramnios and explore the impact of patient variables on outcome and prognosis.

Methods

A retrospective single-center study was conducted analyzing 104 pregnancies complicated by oligohydramnios of renal origin from 2001 to 2011. Statistical analysis was performed to assess the influence of pre- and postnatal data on pregnancy outcome, morbidity and mortality.

Results

Prenatal renal diagnoses were as follows: hydronephrosis/megaureter: n = 21 (20.2 %), aberrance in renal form or location: n = 7 (6.7 %), cystic renal disease: n = 28 (26.9 %), renal dysplasia: n = 24 (23.1 %), renal agenesis: n = 42 (30.4 %), posterior urethral valves: n = 11 (10.6 %). Hydronephrosis/megaureter and late onset of oligohydramnios were prognostic factors for fetal survival, whereas renal agenesis and associated anomalies had a negative impact on pregnancy outcome. Prenatal interventions did not improve prognosis.

Conclusions

Pregnancies complicated by renal oligohydramnios still have a poor outcome. Careful weighing of prognostic factors is necessary to decide about further therapeutic measures.

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Title: Renal oligo- and anhydramnios: cause, course and outcome—a single-center study
Authors: Judith Eva Spiro
Martin Konrad
Esther Rieger-Fackeldey
Katja Masjosthusmann
Susanne Amler
Walter Klockenbusch
Ralf Schmitz
Publication date: 01-08-2015
Publisher: Springer Berlin Heidelberg
Published in: Archives of Gynecology and Obstetrics / Issue 2/2015
Print ISSN: 0932-0067
Electronic ISSN: 1432-0711
DOI: https://doi.org/10.1007/s00404-015-3648-7

At a glance: The ONWARDS insulin icodec trials

Springer Medicine

Renal oligo- and anhydramnios: cause, course and outcome—a single-center study

Abstract

Purpose

Methods

Results

Conclusions

At a glance: The ONWARDS insulin icodec trials

Springer Medicine

Abstract

Purpose

Methods

Results

Conclusions

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