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Archives of Gynecology and Obstetrics
Published in: Archives of Gynecology and Obstetrics 6/2015

01-06-2015 | General Gynecology

Hysteroscopy in women with abnormal uterine bleeding: a meta-analysis on four major endometrial pathologies

Authors: Fani Gkrozou, George Dimakopoulos, Thomas Vrekoussis, Lazaros Lavasidis, Anastasios Koutlas, Iordanis Navrozoglou, Theodore Stefos, Minas Paschopoulos

Published in: Archives of Gynecology and Obstetrics | Issue 6/2015

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Abstract

Purpose

To determine the accuracy of hysteroscopy in diagnosing endometrial cancer, hyperplasia, polyps and submucous myomas.

Methods

Relevant articles were retrieved from the MEDLINE and the Cochrane Library (1986–2011). Studies were selected blindly. Results for diagnostic accuracy were extracted to form separate 2 × 2 tables (for endometrial cancer, hyperplasia, polyps and submucous myomas). A summary sensitivity and specificity point reflected the average accuracy observed. Summary ROCs (SROCs) were also calculated according to the HSROC model.

Results

For endometrial cancer, the estimated sensitivity was 82.6 % (95 % CR 66.9–91.8 %) and the specificity was 99.7 % (95 % CR 98.1–99.9 %). For endometrial hyperplasia, sensitivity was 75.2 % (95 % CR 55.4–88.1 %), while specificity was 91.5 % (95 % CR 85.7–95.0 %). For endometrial polyps, sensitivity was 95.4 % (95 % CR 87.4–98.4 %) and specificity was 96.4 % (95 % CR 93.7–98.0 %). Finally, for submucous myomas, sensitivity was estimated to 97.0 % (95 % CR 89.8–99.2 %) and specificity to 98.9 % (95 % CR 93.3–99.8 %).

Conclusions

Diagnostic accuracy for hysteroscopy is high for endometrial cancer, polyps and submucous myomas, but only moderate for endometrial hyperplasia.
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Metadata
Title
Hysteroscopy in women with abnormal uterine bleeding: a meta-analysis on four major endometrial pathologies
Authors
Fani Gkrozou
George Dimakopoulos
Thomas Vrekoussis
Lazaros Lavasidis
Anastasios Koutlas
Iordanis Navrozoglou
Theodore Stefos
Minas Paschopoulos
Publication date
01-06-2015
Publisher
Springer Berlin Heidelberg
Published in
Archives of Gynecology and Obstetrics / Issue 6/2015
Print ISSN: 0932-0067
Electronic ISSN: 1432-0711
DOI
https://doi.org/10.1007/s00404-014-3585-x

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