Top

Archives of Gynecology and Obstetrics

Published in:

01-11-2013 | Maternal-Fetal Medicine

RETRACTED ARTICLE: Does immediate postpartum curettage of the endometrium accelerate recovery from preeclampsia–eclampsia? A randomized controlled trial

Authors: A. Ragab, H. Goda, M. Raghib, R. Barakat, A. El-Samanoudy, A. Badawy

Published in: Archives of Gynecology and Obstetrics | Issue 5/2013

Abstract

Objectives

To evaluate the effect of immediate postpartum curettage on rapid resolution of clinical and laboratory indices in pre-eclampsia and eclampsia women.

Methods

A randomized controlled study, comprised of 420 pre-eclamptic or eclamptic women with singleton pregnancy 24 weeks gestation and more. Patients were divided into two groups: 220 patients underwent immediate postpartum curettage and 200 patients as a control group.

Results

The clinical and laboratory prenatal parameters showed no statistical significant differences between both groups. The follow-up for the postnatal clinical and laboratory data showed significant improvement for the mean arterial blood pressure in the curettage group over 6, 12, and 24 h after delivery and significant improvement in the platelet count as well. The average time required for MAP to reach 105 mmHg or less was significantly shorter (P < 0.05) in the curettage group (40 ± 3.15 h) than the control group (86 ± 5.34 h). Two patients in the curettage group developed convulsions versus 11 patients in the control group within the first 24 h after delivery. No maternal mortalities were reported in both groups.

Conclusion

Immediate postpartum curettage is a safe and effective procedure and can accelerate recovery from pre-eclampsia or eclampsia.

Roberts JM, Pearson G, Cutler J, Lindheimer M (2003) Summary of the NHLBI Working Group on Research on Hypertension During Pregnancy. Hypertension 41:437–445CrossRefPubMed

Chang J, Elam-Evans LD, Berg CJ, Herndon J, Flowers L, Seed KA (2003) Pregnancy-related mortality surveillance-United States 1991–1999. MMWR Surveill Summ 52(2):1–8PubMed

Sibai BM, Ewell M, Levine RJ, KlebanoV MA, Esterlitz J, Catalano PM (1997) Risk factors associated with preeclampsia in healthy nulliparous women. The Calcium for Preeclampsia Prevention (CPEP) Study Group. Am J Obstet Gynecol 177:1003–1010CrossRefPubMed

Bombrys AE, Barton JR, Nowacki EA, Habli M, Pinder L, How H (2008) Expectant management of severe preeclampsia at less than 27 weeks’ gestation: maternal and perinatal outcomes according to gestational age by weeks at onset of expectant management. Am J Obstet Gynecol 199(3):247–252CrossRefPubMed

Hnat MD, Sibai BM, Caritis S, Hauth J, Lindheimer MD, MacPherson C (2008) Perinatal outcome in women with recurrent preeclampsia compared with women who develop preeclampsia as nulliparas. Am J Obstet Gynecol 186:422–426CrossRef

Gaugler-Senden IP, Huijssoon AG, Visser W, Steegers EA, de Groot CJ (2006) Maternal and perinatal outcome of preeclampsia with an onset before 24 weeks’ gestation. Audit in a tertiary referral center. Eur J Obstet Gynecol Reprod Biol 128(1–2):216–221CrossRefPubMed

Jantasing S, Tanawattanacharoen S (2006) Perinatal outcomes in severe preeclamptic women between 24–33 (+6) weeks’ gestation. J Med Assoc Thai 91(1):25–30

Sibai BM, Caritis S, Hauth J (2003) National Institute of Child Health and Human Development Maternal-Fetal Medicine Units Network. What we have learned about preeclampsia. Semin Perinatol 27:239–246CrossRefPubMed

Duley L (1992) Maternal mortality associated with hypertensive disorders of pregnancy in Africa, Asia, Latin America, and Carribean. Br J Obstet Gynaecol 99:547–553CrossRefPubMed

10.

Steegers EA, von Dadelszen P, Duvekot JJ, Pijnenborg R (2010) Pre-eclampsia. Lancet 376(9741):631–644CrossRefPubMed

11.

Szarka A, Rigó J Jr, Lázár L, Beko G, Molvarec A (2010) Circulating cytokines, chemokines, and adhesion molecules in normal pregnancy and preeclampsia determined by multiplex suspension array. BMC Immunol 11:59CrossRefPubMedPubMedCentral

12.

Molvarec A, Szarka A, Walentin S, Szucs E, Nagy B, Rigó J Jr (2010) Circulating angiogenic factors determined by electrochemiluminescence immunoassay in relation to the clinical features and laboratory parameters in women with pre-eclampsia. Hypertens Res 33(9):892–898CrossRefPubMed

13.

Hunter CA, Howard WF (1960) A pressor substance (hysterotonin) occurring in toxemia. Am J Obstet Gynecol 79:838–846CrossRefPubMed

14.

Pritchard JA, MacDonald PC, Gant NF (1985) Williams obstetrics, 17th edn. Appleton Century Crofts, Norwalk, pp 525–560

15.

Hunter CA, Howard WF, McCormick CO (1961) Amelioration of the hypertension of toxemia by postpartum curettage. Am J Obstet Gynecol 81:884–889CrossRefPubMed

16.

Everett F, Magann EF, Martin JN (1995) New onset hypertension in the pregnant patient. Obstet Gynecol Clin North Am 22:157–172CrossRef

17.

Chandra M, Bhardwaj B (1998) Our experience with use of magnesium sulfate in eclampsia. J Obstet Gynecol India 48:38–42

18.

Fejgin MD, Charles AG (1993) Immediate postpartum curettage: accelerated recovery from severe preeclampsia. Obstet Gynecol 82(1):163–164PubMed

19.

Alkan A, Tugrul S, Oral O, Uslu H, Köse D, Catakli FT (2006) Effects of postpartum uterine curettage on maternal well-being in severe preeclamptic patients. Clin Exp Obstet Gynecol 33(1):55–58PubMed

20.

Magann EF, Martin JN, Isaacs JP et al (1993) Immediate postpartum curettage: accelerated recovery from severe preeclampsia. Obstet Gynecol 81:502–506PubMed

21.

Witlin AG, Sadde GR, Mattar F et al (1999) Risk factors for abruption placentae and eclampsia: analysis of 445 consecutively managed women with severe preeclampsia and eclampsia. Am J Obstet Gynecol 180:1322–1329CrossRefPubMed

Title: RETRACTED ARTICLE: Does immediate postpartum curettage of the endometrium accelerate recovery from preeclampsia–eclampsia? A randomized controlled trial
Authors: A. Ragab
H. Goda
M. Raghib
R. Barakat
A. El-Samanoudy
A. Badawy
Publication date: 01-11-2013
Publisher: Springer Berlin Heidelberg
Published in: Archives of Gynecology and Obstetrics / Issue 5/2013
Print ISSN: 0932-0067
Electronic ISSN: 1432-0711
DOI: https://doi.org/10.1007/s00404-013-2866-0

At a glance: The STEP trials

Springer Medicine

RETRACTED ARTICLE: Does immediate postpartum curettage of the endometrium accelerate recovery from preeclampsia–eclampsia? A randomized controlled trial

Abstract

Objectives

Methods

Results

Conclusion

At a glance: The STEP trials

Springer Medicine

Abstract

Objectives

Methods

Results

Conclusion

Please log in to get access to this content

Other articles of this Issue 5/2013

Dilemmas encountered while dealing a pregnancy complicated by pelvic Hydatid disease

Mirror syndrome associated with Fetal Hemoglobin Bart’s disease: a case report

Polymorphisms in MTHFR, MTHFD, and PAI-1 and recurrent miscarriage among North Indian women

Analysis of SYCP3 encoding synaptonemal complex protein 3 in human aneuploidies

Direct colposcopic vision used with the LLETZ procedure for optimal treatment of CIN: results of joint cohort studies

Signal quality of non-invasive fetal electrocardiogram in vaginal breech delivery: a case–controlled study