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01-10-2012 | Materno-Fetal Medicine

A randomized controlled trial for cervical priming using vaginal misoprostol prior to hysteroscopy in women who have only undergone cesarean section

Authors: Emmanouil Kalampokas, Chrisostomos Sofoudis, George Antonogeorgos, Konstantinos Panoulis, Leon Aravantinos, Odysseas Grigoriou, Theodoros Kalampokas

Published in: Archives of Gynecology and Obstetrics | Issue 4/2012

Abstract

Purpose

To evaluate the efficacy of misoprostol administrated vaginally on cervical priming and its complications prior to diagnostic or operative hysteroscopy in women who have undergone at least one cesarean section and who have never delivered vaginally before and/or had other transcervical procedure.

Methods

A total of 55 patients undergoing hysteroscopy for various intra-uterine lesions were included in this study and were randomly allocated to two groups finally. Thirty patients in the study group were given 200 μg misoprostol vaginally 12 h before the procedure, whereas 25 patients in the control group did not receive any cervical priming. The countered outcome included the cervical width detected with Hegar dilatators and complication rates.

Results

Mean cervical width was greater in the study group (6.6 ± 1.3) than in the control group (5.1 ± 0.9). Complications and failure rates were lower in the study group.

Conclusion

Application of 200 μg misoprostol vaginally 12 h before hysteroscopy softens the cervix, reduces cervical resistance and consequently the need for cervical dilatation, with only mild side effects.

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Title: A randomized controlled trial for cervical priming using vaginal misoprostol prior to hysteroscopy in women who have only undergone cesarean section
Authors: Emmanouil Kalampokas
Chrisostomos Sofoudis
George Antonogeorgos
Konstantinos Panoulis
Leon Aravantinos
Odysseas Grigoriou
Theodoros Kalampokas
Publication date: 01-10-2012
Publisher: Springer-Verlag
Published in: Archives of Gynecology and Obstetrics / Issue 4/2012
Print ISSN: 0932-0067
Electronic ISSN: 1432-0711
DOI: https://doi.org/10.1007/s00404-012-2374-7

At a glance: The STEP trials

Springer Medicine

A randomized controlled trial for cervical priming using vaginal misoprostol prior to hysteroscopy in women who have only undergone cesarean section

Abstract

Purpose

Methods

Results

Conclusion

At a glance: The STEP trials

Springer Medicine

Abstract

Purpose

Methods

Results

Conclusion

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