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Archives of Gynecology and Obstetrics
Published in: Archives of Gynecology and Obstetrics 2/2011

01-02-2011 | Gynecologic Oncology

Unusual form of superficial spreading squamous cell carcinoma of cervix involving the endometrium, bilateral tubes and ovaries: a case report with literature review

Authors: Tayfun Gungor, Sunduz Ozlem Altinkaya, Mustafa Ozat, Serap Akbay, Leyla Mollamahmutoglu

Published in: Archives of Gynecology and Obstetrics | Issue 2/2011

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Abstract

Objective

Although the majority of metastatic ovarian tumors arise within the female genital tract, squamous cell carcinoma of the cervix is a rare form of metastases to the bilateral ovaries by endometrial and transtubal spreading.

Case

A 53-year-old woman was referred to the oncology clinic with postmenopausal bleeding. On vaginal examination, a 3 cm tumor arising from the cervix was inspected. Multiple cervical biopsies and endocervical curettage revealed large cell, non-keratinized squamous cell cervix carcinoma. Radical hysterectomy and bilateral salpingo-oophorectomy were performed. Bilateral pelvic and para-aortic lymph nodes were also removed. The final pathology report revealed endometrial, focal myometrial, bilateral tubal mucosal, fimbrial and bilateral ovarian squamous cell carcinoma involvement. Pelvic and para-aortic nodes were free from metastases.

Conclusion

Although the incidence of ovarian metastases of adenocarcinoma of the cervix is significantly higher, squamous cell carcinoma may also metastasize to the ovaries by endometrial and transtubal spreading in the absence of lymph node involvement. Especially in young patients for whom preservation of the ovaries is supposed, gross intraoperative inspection of the radical hysterectomy specimen and endometrium should be done and ovaries should be evaluated carefully.
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Metadata
Title
Unusual form of superficial spreading squamous cell carcinoma of cervix involving the endometrium, bilateral tubes and ovaries: a case report with literature review
Authors
Tayfun Gungor
Sunduz Ozlem Altinkaya
Mustafa Ozat
Serap Akbay
Leyla Mollamahmutoglu
Publication date
01-02-2011
Publisher
Springer-Verlag
Published in
Archives of Gynecology and Obstetrics / Issue 2/2011
Print ISSN: 0932-0067
Electronic ISSN: 1432-0711
DOI
https://doi.org/10.1007/s00404-010-1672-1

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