Published in:
01-02-2011 | Short Communication
Polycythemia vera and pregnancy: experience of four pregnancies in a single patient
Authors:
Neelam Aggarwal, Seema Chopra, Vanita Suri, Pooja Sikka, Aditi Goundan, Pankaj Malhotra
Published in:
Archives of Gynecology and Obstetrics
|
Issue 2/2011
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Abstract
Introduction
The association of polycythemia vera (PV) and pregnancy is rare. The estimated incidence ranges from 0.04 per 100,000 in women aged 20–34 years to 0.25 per 100,000 in those aged 35–39 years. The management of pregnant patient with PV may be problematic; less than 50 pregnancies have been reported so far in PV.
Material and methods
We hereby describe four pregnancies in a woman where PV was diagnosed in the fourth pregnancy. Aspirin and phlebotomy were used to maintain cell count in normal range and to avoid thrombotic complications.
Conclusion
Pregnancy in PV appears to be associated with significantly better outcome with tailor-made management for achieving good hematocrit control, low-dose aspirin and good maternal and fetal surveillance.