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Archives of Gynecology and Obstetrics

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01-04-2011 | Materno-fetal Medicine

Causes and consequences of 93 fetuses with cardiomegaly in a tertiary center in Thailand

Authors: Piyawadee Wuttikonsammakit, Boonchai Uerpairojkit, Somchai Tanawattanacharoen

Published in: Archives of Gynecology and Obstetrics | Issue 4/2011

Abstract

Objectives

To assess etiology, perinatal mortality and associated factors of fetal cardiomegaly (FC).

Methods

A retrospective study of fetuses with cardiomegaly was conducted. Demographic data, ultrasonographic findings, and outcomes were collected and analyzed.

Results

Ninety-three fetuses were analyzed. The causes of FC were cardiac causes 49.5%, Bart’s hemoglobinopathies 28%, and non-Bart’s anemia 15%. Ascites, pericardial effusion, and hydrops were more prevalent in fetuses with anemia than those with cardiac abnormalities. The overall perinatal mortality was 69.9%. Although all Bart’s hydrops died, perinatal mortality of non-Bart’s anemia, and structural cardiac defect were 57.1 and 69.7%, respectively. Excluding Bart’s anemia, receiver-operating characteristic curve analysis demonstrated that cardiothoracic ratio of ≥0.58 best predictive for perinatal mortality. Earlier gestational age at diagnosis, skin edema, and chromosomal abnormality were associated with higher mortality.

Conclusions

Majority causes of FC were cardiac and anemic in origin. It carried high-perinatal mortality depending on the causes.

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Title: Causes and consequences of 93 fetuses with cardiomegaly in a tertiary center in Thailand
Authors: Piyawadee Wuttikonsammakit
Boonchai Uerpairojkit
Somchai Tanawattanacharoen
Publication date: 01-04-2011
Publisher: Springer-Verlag
Published in: Archives of Gynecology and Obstetrics / Issue 4/2011
Print ISSN: 0932-0067
Electronic ISSN: 1432-0711
DOI: https://doi.org/10.1007/s00404-010-1426-0

Keynote webinar | Spotlight on medication adherence

Springer Medicine

Causes and consequences of 93 fetuses with cardiomegaly in a tertiary center in Thailand

Abstract

Objectives

Methods

Results

Conclusions

Keynote webinar | Spotlight on medication adherence

Springer Medicine

Abstract

Objectives

Methods

Results

Conclusions

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