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Published in: Archives of Gynecology and Obstetrics 2/2011

01-02-2011 | General Gynecology

Oxidant/antioxidant status in premenstrual syndrome

Authors: Candan Iltemir Duvan, Ahmet Cumaoglu, Nilgun Ozturk Turhan, Cimen Karasu, Hasan Kafali

Published in: Archives of Gynecology and Obstetrics | Issue 2/2011

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Abstract

Purpose

To investigate oxidant/antioxidant status in premenstrual syndrome (PMS).

Methods

Study group (n = 20) consisted of PMS and control group (n = 21) consisted of normal menstruating women. The serum oxidant status was assessed by the lipid hydroperoxide (LHP), malondialdehyde (MDA) and protein carbonyl (PC); the antioxidant status was assessed by the total thiol (T-SH) and total antioxidant capacity (TAC).

Results

The study and control groups revealed no statistical difference, in terms of day 3 LHP, MDA, PC, T-SH and TAC levels. There were no significant differences between groups in terms of day 21 MDA, PC and T-SH levels. However, day 21 LHP levels were increased and TAC levels were decreased in the study group compared with the control group.

Conclusion

Increased oxidative stress and reduced antioxidant capacity may occur in PMS. It can be speculated that the imbalance of oxidant/antioxidant systems may be a cause or the consequence of the various stress symptoms in PMS.
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Metadata
Title
Oxidant/antioxidant status in premenstrual syndrome
Authors
Candan Iltemir Duvan
Ahmet Cumaoglu
Nilgun Ozturk Turhan
Cimen Karasu
Hasan Kafali
Publication date
01-02-2011
Publisher
Springer-Verlag
Published in
Archives of Gynecology and Obstetrics / Issue 2/2011
Print ISSN: 0932-0067
Electronic ISSN: 1432-0711
DOI
https://doi.org/10.1007/s00404-009-1347-y

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