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Published in: Archives of Gynecology and Obstetrics 5/2010

Open Access 01-05-2010 | Gynecologic Oncology

Femur metastasis in carcinoma of the uterine cervix: a rare entity

Authors: Giacomo Corrado, Salvatore Santaguida, Gianfranco Zannoni, Giovanni Scambia, Gabriella Ferrandina

Published in: Archives of Gynecology and Obstetrics | Issue 5/2010

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Abstract

Purpose

We report the first case of isolated femur metastasis in a locally advanced cervical cancer (LACC) patients.

Case

A 40-year-old woman presenting with carcinoma of the uterine cervix, FIGO stage IIb was administered concomitant chemo-radiation and achieved clinical partial response. Before the planned surgery, she developed an isolated metastatic lytic lesion of the left femur. After surgical excision of metastasis, she refused palliative chemotherapy, and radiotherapy, and died 3 months later because of progression of the disease.

Conclusion

Bone metastasis is not so infrequent in patients with LACC. Because the prognosis of these patients is poor and most of them die within 1 year after the diagnosis of metastatic disease, the policy of treatment should be directed to maintain their quality of life.
Literature
1.
go back to reference Jemal A, Siegel R, Ward E, Hao Y, Xu J, Murray T, Thun MJ (2008) Cancer statistics, 2008. CA Cancer J Clin 58(2):71–96CrossRefPubMed Jemal A, Siegel R, Ward E, Hao Y, Xu J, Murray T, Thun MJ (2008) Cancer statistics, 2008. CA Cancer J Clin 58(2):71–96CrossRefPubMed
2.
go back to reference Friedlander M, Grogan M (2002) U.S. Preventative Services Task Force. Guidelines for the treatment of recurrent and metastatic cervical cancer. Oncologist 7(4):342–347PubMed Friedlander M, Grogan M (2002) U.S. Preventative Services Task Force. Guidelines for the treatment of recurrent and metastatic cervical cancer. Oncologist 7(4):342–347PubMed
3.
go back to reference Ferrandina G, Legge F, Fagotti A, Fanfani F, Distefano M, Morganti A, Cellini N, Scambia G, 1 (Suppl 1) (2007) Preoperative concomitant chemoradiotherapy in locally advanced cervical cancer: safety, outcome, and prognostic measures. Gynecol Oncol 107(1 Suppl 1):S127–S132CrossRefPubMed Ferrandina G, Legge F, Fagotti A, Fanfani F, Distefano M, Morganti A, Cellini N, Scambia G, 1 (Suppl 1) (2007) Preoperative concomitant chemoradiotherapy in locally advanced cervical cancer: safety, outcome, and prognostic measures. Gynecol Oncol 107(1 Suppl 1):S127–S132CrossRefPubMed
4.
go back to reference Fulcher AS, O’Sullivan SG, Segreti EM, Kavanagh B (1999) Recurrent cervical carcinoma: typical and atypical manifestations. Radiographics 19:S103–S116PubMed Fulcher AS, O’Sullivan SG, Segreti EM, Kavanagh B (1999) Recurrent cervical carcinoma: typical and atypical manifestations. Radiographics 19:S103–S116PubMed
5.
go back to reference Matsuyama T, Tsukamoto N, Imachi M, Nakano H (1989) Bone metastasis from cervix cancer. Gynecol Oncol 32(1):72–75CrossRefPubMed Matsuyama T, Tsukamoto N, Imachi M, Nakano H (1989) Bone metastasis from cervix cancer. Gynecol Oncol 32(1):72–75CrossRefPubMed
6.
go back to reference Pasricha R, Tiwari A, Aggarwal T, Lal P (2006) Carcinoma of uterine cervix with isolated metastasis to fibula and its unusual behavior: report of a case and review of literature. J Cancer Res Ther 2(2):79–81CrossRefPubMed Pasricha R, Tiwari A, Aggarwal T, Lal P (2006) Carcinoma of uterine cervix with isolated metastasis to fibula and its unusual behavior: report of a case and review of literature. J Cancer Res Ther 2(2):79–81CrossRefPubMed
7.
go back to reference Moore DH, Blessing JA, McQuellon RP, Thaler HT, Cella D, Benda J, Miller DS, Olt G, King S, Boggess JF, Rocereto TF (2004) Phase III study of cisplatin with or without paclitaxel in stage IV B, recurrent or persistent squamous cell carcinoma of the cervix: a gynecologic oncology group study. J Clin Oncol 22:3113–3119CrossRefPubMed Moore DH, Blessing JA, McQuellon RP, Thaler HT, Cella D, Benda J, Miller DS, Olt G, King S, Boggess JF, Rocereto TF (2004) Phase III study of cisplatin with or without paclitaxel in stage IV B, recurrent or persistent squamous cell carcinoma of the cervix: a gynecologic oncology group study. J Clin Oncol 22:3113–3119CrossRefPubMed
10.
go back to reference Kidd EA, Siegel BA, Dehdashti F, Rader JS, Mutic S, Mutch DG, Powell MA, Grigsby PW (2009) Clinical outcomes of definitive intensity-modulated radiation therapy with fluorodeoxyglucose-positron emission tomography simulation in patients with locally advanced cervical cancer. Int J Radiat Oncol Biol Phys [Epub ahead of print] Kidd EA, Siegel BA, Dehdashti F, Rader JS, Mutic S, Mutch DG, Powell MA, Grigsby PW (2009) Clinical outcomes of definitive intensity-modulated radiation therapy with fluorodeoxyglucose-positron emission tomography simulation in patients with locally advanced cervical cancer. Int J Radiat Oncol Biol Phys [Epub ahead of print]
Metadata
Title
Femur metastasis in carcinoma of the uterine cervix: a rare entity
Authors
Giacomo Corrado
Salvatore Santaguida
Gianfranco Zannoni
Giovanni Scambia
Gabriella Ferrandina
Publication date
01-05-2010
Publisher
Springer-Verlag
Published in
Archives of Gynecology and Obstetrics / Issue 5/2010
Print ISSN: 0932-0067
Electronic ISSN: 1432-0711
DOI
https://doi.org/10.1007/s00404-009-1307-6

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