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Archives of Gynecology and Obstetrics

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01-05-2010 | Reproductive Medicine

Characterization of the uterine junctional zone prior to IVF/ICSI: an observational study

Authors: Georg Kunz, Dolores Beil

Published in: Archives of Gynecology and Obstetrics | Issue 5/2010

Abstract

Purpose

The uterine junctional zone as documented by magnetic resonance imaging (MRI) has shown to be of significance with respect to the early process of human reproduction. In this study, MRI findings were related to the outcome of an IVF/ICSI program.

Materials and methods

In 113 infertile women, the diameter of the anterior and posterior junctional zone (JZ) myometrium was documented by MRI prior to the use of ART. Each group of women was also subdivided according to the presence (MI/GV > 0%) or absence (MI/GV = 0%) of metaphase I(MI) and germinal vesicle (GV) oocytes. The MRI measurements were related to these and further parameters like expansion of the cumulus oophorus, pronuclei stages, embryo morphology and pregnancy rates.

Results

In all women with MI/GV = 0%, the JZ myometrium was significantly enlarged (p < 0.004) and the clinical pregnancy rate was significantly lower (p < 0.025) when compared to the women with MI/GV > 0%. The baby take home rates tended to the same results, but were not significantly different. No direct influence of the JZ on all other parameters could be observed.

Conclusions

The JZ, as documented by MRI, might interfere with follicular function.

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Title: Characterization of the uterine junctional zone prior to IVF/ICSI: an observational study
Authors: Georg Kunz
Dolores Beil
Publication date: 01-05-2010
Publisher: Springer-Verlag
Published in: Archives of Gynecology and Obstetrics / Issue 5/2010
Print ISSN: 0932-0067
Electronic ISSN: 1432-0711
DOI: https://doi.org/10.1007/s00404-009-1285-8

At a glance: The STEP trials

Springer Medicine

Characterization of the uterine junctional zone prior to IVF/ICSI: an observational study

Abstract

Purpose

Materials and methods

Results

Conclusions

At a glance: The STEP trials

Springer Medicine

Abstract

Purpose

Materials and methods

Results

Conclusions

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