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Published in: Archives of Gynecology and Obstetrics 5/2010

01-05-2010 | Original Article

Pregnancy outcome of patients with dermoid and other benign ovarian cysts

Authors: Lisa Katz, Amalia Levy, Arnon Wiznitzer, Eyal Sheiner

Published in: Archives of Gynecology and Obstetrics | Issue 5/2010

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Abstract

Objective

To investigate pregnancy outcome of patients with dermoid and other benign ovarian cysts.

Methods

A population-based study comparing all pregnancies of women with and without benign ovarian cysts was conducted. Deliveries occurred during the years 1988–2007 at Soroka University Medical Center. A multivariate logistic regression model, with backward elimination, was constructed to find independent risk factors associated with benign ovarian cysts.

Results

During the study period there were 212,114 deliveries, of which 93 occurred in patients with benign ovarian cysts. Most of the lesions were benign cyatadenoma (41.9%), 36.7% were dermoid cyst, and 11.8% were adenofibroma, mostly diagnosed during cesarean delivery (76.3%). Others (12.9%) were diagnosed during pregnancy by ultrasonography and the remaining 10.8% were diagnosed before pregnancy. The mean diameter at diagnosis was 9.05 ± 7.6 cm for cystadenoma, 6.09 ± 3.0 cm for dermoid cyst and 4.55 ± 4.1 cm for adenofibroma. Only 3 cases of ovarian torsion were noted (3.2%), and 15 cases of hospitalization due to abdominal pain (16.2%). The following conditions were significantly associated with benign ovarian cysts: hypertensive disorder [odds ratio (OR) 3.05; 95% confidence interval (CI) 1.87–4.97], and maternal age (OR 1.04; 95% CI 1.01–1.07). Ovarian dermoid cyst was significantly associated with fertility treatments (8.6 vs. 2.4% OR = 3.75; 95% CI 1.1–12.2; P = 0.019). In addition, after controlling for maternal age using a multivariate analysis, fertility treatments remained significantly associated with ovarian dermoid. No significant differences were noted between the groups regarding perinatal outcomes such as birth weight, low birth weight, congenital malformations, low Apgar scores, or perinatal mortality.

Conclusion

The course of pregnancy of patients with dermoid and other benign ovarian cysts, including perinatal outcomes, is favorable. The cysts should be managed conservatively if possible with routine ultrasound follow up during the pregnancy since complications are extremely rare.
Literature
1.
go back to reference Hill LM, Connors-beatty DJ, Nowak A, Tush B (1998) The role of ultrasonography in the detection and management of adnexal masses during the second and third trimester of pregnancy. Am J Obstet Gynecol 179:703–707CrossRefPubMed Hill LM, Connors-beatty DJ, Nowak A, Tush B (1998) The role of ultrasonography in the detection and management of adnexal masses during the second and third trimester of pregnancy. Am J Obstet Gynecol 179:703–707CrossRefPubMed
2.
go back to reference Nair U (2005) Acute abdomen and abdominal pain in pregnancy. Curr Obstet Gynaecol 15:359–367CrossRef Nair U (2005) Acute abdomen and abdominal pain in pregnancy. Curr Obstet Gynaecol 15:359–367CrossRef
3.
go back to reference Platek DN, Henderson CE, Goldberg GL (1995) The management of a persistent adnexal mass in pregnancy. Am J Obstet Gynecol 173:1236–1240CrossRefPubMed Platek DN, Henderson CE, Goldberg GL (1995) The management of a persistent adnexal mass in pregnancy. Am J Obstet Gynecol 173:1236–1240CrossRefPubMed
4.
5.
go back to reference Caspi B, Appelman Z, Rabinerson D, Zalel Y, Tulandi T, Shoham Z (1997) The growth pattern of ovarian dermoid cysts: a prospective study in premenopausal and postmenopausal women. Fertil Steril 68:501–505CrossRefPubMed Caspi B, Appelman Z, Rabinerson D, Zalel Y, Tulandi T, Shoham Z (1997) The growth pattern of ovarian dermoid cysts: a prospective study in premenopausal and postmenopausal women. Fertil Steril 68:501–505CrossRefPubMed
6.
go back to reference Caspi B, Levi R, Appelman Z, Rabinerson D, Goldman G, Hagay Z (2000) Conservative management of ovarian cystic teratoma during pregnancy and labor. Am J Obstet Gynecol 182:503–505CrossRefPubMed Caspi B, Levi R, Appelman Z, Rabinerson D, Goldman G, Hagay Z (2000) Conservative management of ovarian cystic teratoma during pregnancy and labor. Am J Obstet Gynecol 182:503–505CrossRefPubMed
7.
go back to reference Parker WH, Childers JM, Canis M, Phillips DR, Topel H (1996) Laparoscopic management of benign cystic teratomas during pregnancy. Am J Obstet Gynecol 174:1499–1501CrossRefPubMed Parker WH, Childers JM, Canis M, Phillips DR, Topel H (1996) Laparoscopic management of benign cystic teratomas during pregnancy. Am J Obstet Gynecol 174:1499–1501CrossRefPubMed
8.
go back to reference Sherard GB 3rd, Hodson CA, Williams HJ, Semer DA, Hadi HA, Tait DL (2003) Adnexal masses and pregnancy: a 12-year experience. Am J Obstet Gynecol 189:358–362CrossRefPubMed Sherard GB 3rd, Hodson CA, Williams HJ, Semer DA, Hadi HA, Tait DL (2003) Adnexal masses and pregnancy: a 12-year experience. Am J Obstet Gynecol 189:358–362CrossRefPubMed
9.
go back to reference Schmeler KM, Mayo-Smith WW, Peipert JF, Weitzen S, Manuel MD, Gordinier ME (2005) Adnexal masses in pregnancy: surgery compared with observation. Obstet Gynecol 105:1098–1103PubMed Schmeler KM, Mayo-Smith WW, Peipert JF, Weitzen S, Manuel MD, Gordinier ME (2005) Adnexal masses in pregnancy: surgery compared with observation. Obstet Gynecol 105:1098–1103PubMed
10.
go back to reference Hong JY (2006) Adnexal mass surgery and anesthesia during pregnancy: a 10-year retrospective review. Int J Obstet Anesth 15:212–216CrossRefPubMed Hong JY (2006) Adnexal mass surgery and anesthesia during pregnancy: a 10-year retrospective review. Int J Obstet Anesth 15:212–216CrossRefPubMed
11.
go back to reference Usui R, Minakami H, Kosuge S, Iwasaki R, Ohwada M, Sato I (2000) A retrospective survey of clinical, pathologic, and prognostic features of adnexal masses operated on during pregnancy. J Obstet Gynaecol Res 26(2):89–93PubMedCrossRef Usui R, Minakami H, Kosuge S, Iwasaki R, Ohwada M, Sato I (2000) A retrospective survey of clinical, pathologic, and prognostic features of adnexal masses operated on during pregnancy. J Obstet Gynaecol Res 26(2):89–93PubMedCrossRef
12.
go back to reference Whitecar MP, Turner S, Higby MK (1999) Adnexal masses in pregnancy: a review of 130 cases undergoing surgical management. Am J Obstet Gynecol 181(1):19–24CrossRefPubMed Whitecar MP, Turner S, Higby MK (1999) Adnexal masses in pregnancy: a review of 130 cases undergoing surgical management. Am J Obstet Gynecol 181(1):19–24CrossRefPubMed
13.
go back to reference Walid MS, Boddy MG (2009) Bilateral dermoid cysts of the ovary in a pregnant woman: case report and review of the literature. Arch Gynecol Obstet 279(2):105–108CrossRefPubMed Walid MS, Boddy MG (2009) Bilateral dermoid cysts of the ovary in a pregnant woman: case report and review of the literature. Arch Gynecol Obstet 279(2):105–108CrossRefPubMed
Metadata
Title
Pregnancy outcome of patients with dermoid and other benign ovarian cysts
Authors
Lisa Katz
Amalia Levy
Arnon Wiznitzer
Eyal Sheiner
Publication date
01-05-2010
Publisher
Springer-Verlag
Published in
Archives of Gynecology and Obstetrics / Issue 5/2010
Print ISSN: 0932-0067
Electronic ISSN: 1432-0711
DOI
https://doi.org/10.1007/s00404-009-1158-1

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