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Archives of Gynecology and Obstetrics

Published in:

01-08-2009 | Letter to the Editor

Peritoneal tuberculosis with elevated serum Ca-125 level mimicking advanced stage ovarian cancer: a case report

Authors: Orkun Tan, Edward Luchansky, Stephen Rosenman, Tarah Pua, Masoud Azodi

Published in: Archives of Gynecology and Obstetrics | Issue 2/2009

Abstract

Background

Tuberculosis is still a common problem in immigrant population with peritoneal tuberculosis as the most common presentation of extrapulmonary disease.

Case

A 36-year-old woman presented with abdominal distention, night sweats and weight loss. Physical examination and radiologic studies revealed ascites, omental caking and bilateral enlarged ovaries with an elevated serum Ca-125 of 353 U/mL. Acid-fast stain and culture were negative for Mycobacterium tuberculosis. Diagnostic laparoscopy and biopsy revealed multiple granulomas with epithelioid cells and caseification necrosis confirming tuberculosis. Treatment with anti-tuberculin drugs resulted in resolution of symptoms with a reduction in Ca-125 to normal.

Conclusion

Laparoscopic biopsy with frozen section evaluation would spare patients with peritoneal tuberculosis from unnecessary extensive surgery. Serum Ca-125 level may be useful in monitoring treatment response.

Straughn JM, Robertson MW, Partridge EE (2000) A patient presenting with a pelvic mass, elevated CA-125, and fever. Gynecol Oncol 77:471–472. doi:10.1006/gyno.2000.5756 PubMedCrossRef

Wu JF, Li HJ, Lee PI, Ni YH, Yu SC, Chang MH (2003) Tuberculous peritonitis mimicking peritonitis carcinomatosis: a case report. Eur J Pediatr 162:853–855. doi:10.1007/s00431-003-1319-3 PubMedCrossRef

Bilgin T, Karabay A, Dolar E, Develioglu OH (2001) Peritoneal tuberculosis with pelvic abdominal mass, ascites and elevated CA 125 mimicking advanced ovarian carcinoma: a series of 10 cases. Int J Gynecol Cancer 11:290–294. doi:10.1046/j.1525-1438.2001.011004290.x PubMedCrossRef

Koc S, Beydilli G, Tulunay G, Ocalan R, Boran N, Ozgul N et al (2006) Peritoneal tuberculosis mimicking advanced ovarian cancer: a retrospective review of 22 cases. Gynecol Oncol 103:565–569. doi:10.1016/j.ygyno.2006.04.010 PubMedCrossRef

Title: Peritoneal tuberculosis with elevated serum Ca-125 level mimicking advanced stage ovarian cancer: a case report
Authors: Orkun Tan
Edward Luchansky
Stephen Rosenman
Tarah Pua
Masoud Azodi
Publication date: 01-08-2009
Publisher: Springer-Verlag
Published in: Archives of Gynecology and Obstetrics / Issue 2/2009
Print ISSN: 0932-0067
Electronic ISSN: 1432-0711
DOI: https://doi.org/10.1007/s00404-009-0946-y

At a glance: The ONWARDS insulin icodec trials

Springer Medicine

Peritoneal tuberculosis with elevated serum Ca-125 level mimicking advanced stage ovarian cancer: a case report

Abstract

Background

Case

Conclusion

At a glance: The ONWARDS insulin icodec trials

Springer Medicine

Abstract

Background

Case

Conclusion

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