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Published in: Archives of Gynecology and Obstetrics 3/2009

01-03-2009 | Letter to the Editor

Tisseel for management of traumatic postpartum haemorrhage

Authors: Jaya Saxena Dhulkotia, M. Alazzam, A. Galimberti

Published in: Archives of Gynecology and Obstetrics | Issue 3/2009

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Abstract

Introduction

Following the introduction of haemostatic agents, new opportunities are available when facing problematic bleeding. We report the first case of traumatic postpartum hemorrhage successfully controlled with a fibrin sealant.

Case presentation

26-year nulliparous patient had a rotational forceps delivery and developed multiple vaginal lacerations. Haemostasis could not be achieved after suturing, vaginal packing and IV tranaxemic acid. She lost approx. 3,500 ml blood and received 4 U transfusion. Tisseel was used as a thin layer on vaginal wall and bleeding settled. She had good recovery and perineum healed well.

Conclusion

Tisseel consists of a two-component fibrin biomatrix to stop diffuse bleeding. When the tissues are very oedematous, it can be difficult to insert sutures. We tried this innovative option with very effective results. The absence of long-term complications is reassuring and we recommend its use in similarly extreme situations.
Literature
1.
go back to reference CEMACH (2007) Haemorrage. In: Saving Mothers Lives 2003–2005. CEMACH, London, pp 78–91 CEMACH (2007) Haemorrage. In: Saving Mothers Lives 2003–2005. CEMACH, London, pp 78–91
2.
go back to reference Redl H, Shlag G (1986) Properties of different tissue sealants with special emphasis on fibrinogen based preparations. In: Otorhinolaryngology, vol 1. Springer, Heidelberg, pp 27–38 Redl H, Shlag G (1986) Properties of different tissue sealants with special emphasis on fibrinogen based preparations. In: Otorhinolaryngology, vol 1. Springer, Heidelberg, pp 27–38
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go back to reference TISSEEL (fibrin sealant) (2005) Full prescribing information. 0707074 TISSEEL (fibrin sealant) (2005) Full prescribing information. 0707074
6.
go back to reference FLOSEAL (Hemostatic Matrix) (2005) Full prescribing information. 0706463 FLOSEAL (Hemostatic Matrix) (2005) Full prescribing information. 0706463
Metadata
Title
Tisseel for management of traumatic postpartum haemorrhage
Authors
Jaya Saxena Dhulkotia
M. Alazzam
A. Galimberti
Publication date
01-03-2009
Publisher
Springer-Verlag
Published in
Archives of Gynecology and Obstetrics / Issue 3/2009
Print ISSN: 0932-0067
Electronic ISSN: 1432-0711
DOI
https://doi.org/10.1007/s00404-008-0824-z

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