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Archives of Gynecology and Obstetrics
Published in: Archives of Gynecology and Obstetrics 3/2004

01-11-2004 | Case Report

Large cell neuroendocrine carcinoma of the uterine cervix: a report of a case and review of the literature

Authors: Yilmaz Dikmen, Mert Kazandi, Osman Zekioglu, Aydin Ozsaran, Mustafa Cosan Terek, Yildiz Erhan

Published in: Archives of Gynecology and Obstetrics | Issue 3/2004

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Abstract

Introduction

Large cell neuroendocrine carcinoma is a rare aggressive cervical neoplasm, considerably rarer than the well-recognized small cell neuroendocrine carcinoma of the cervix. Cervical large cell neuroendocrine carcinomas are distinctive cervical carcinomas that are frequently misdiagnosed and have an unfavorable outcome, similar to that of small cell carcinoma.

Case report

We report a 45-year-old woman with large cell neuroendocrine uterine cervical carcinoma.
Literature
1.
Albores-Saavedra J, Gersell D, Gilks CB (1997) Terminology of endocrine tumors of the uterine cervix: results of a workshop sponsored by the College of American Pathologists and the National Cancer Institute. Arch Pathol Lab Med 121:34–39PubMed
2.
Gilks CB, Young RB, Gersell DJ, Clement PB (1997) Large cell neuroendocrine carcinoma of the uterine cervix: a clinicopathologic study of 12 cases. Am J Surg Pathol 21:905–914CrossRefPubMed
3.
Grayson W, Rhemtula H, Taylor LF, Allard U, Tiltman AJ (2002) Detection of human papillomavirus in large cell neuroendocrine carcinoma of the uterine cervix: a study of 12 cases. J Clin Pathol 55:108–114PubMed
4.
Kim YB, Barbuto D, Lagasse LD, Karlan BY (1996) Successful treatment of neuroendocrine small cell carcinoma of the cervix metastatic to regional lymph nodes. Gynecol Oncol 62:411–414CrossRefPubMed
5.
Krivak TC, McBroom JW, Sundborg MJ, Crothers B, Parker MF (2001) Large cell neuroendocrine cervical carcinoma: a report of two cases and review of the literature. Gynecol Oncol 82:187–191CrossRefPubMed
6.
Lewandowski GS, Copeland LJ (1993) A potential role for intensive chemotherapy in the treatment of small cell neuroendocrine tumors of the cervix. Gynecol Oncol 48:127–131CrossRefPubMed
7.
Cui S, Lespinasse P, Cracchiolo B, Sama J, Kreitzer MS, Heller DS (2001) Large cell neuroendocrine carcinoma of the cervix associated with adenocarcinoma in situ: evidence of a common origin. Int J Gynecol Pathol 20:311–312PubMed
8.
O'Hanlan KA, Goldberg GL, Jones JG, Runowicz CD, Ehrlich L, Rodriguez LR (1991) Adjuvant therapy for neuroendocrine small cell carcinoma of the cervix: review of the literature. Gynecol Oncol 43:167–172PubMed
9.
Rhemtula H, Grayson W, van Iddekinge B, Tiltman A (2001) Large-cell neuroendocrine carcinoma of the uterine cervix—a clinicopathological study of five cases. S Afr Med J 91:525–528PubMed
10.
Robboy SJ, Anderson MC, Russell P (2002) Pathology of the female reproductive tract. Malignant tumors of the cervix. Churchill Livingstone, New York, pp 227–229
11.
Savorgaonkar PR, Hale RJ, Muttan J, Monning V, Buckley CH (1996) Neuroendocrine differentiation in cervical carcinoma. J Clin Pathol 49:139–141PubMed
12.
Sheets EE, Berman ML, Hrountas CE, Liao SY, DiSaia PJ (1988) Surgically treated, early-stage neuroendocrine small-cell cervical carcinoma. Obstet Gynecol 71:10–14PubMed
13.
Tsou MH, Tan TD, Cheng SH, Chiou YK (1998) Small cell carcinoma of the uterine cervix with large cell neuroendocrine carcinoma component. Gynecol Oncol 68:69–72CrossRefPubMed
14.
Turner WA, Galloup DG, Talledo OE, Otke LB, Guthrie TH (1986) Neuroendocrine carcinoma of the uterine cervix complicated by pregnancy: case report and review of the literature. Obstet Gynecol 67:80–83
15.
Yun K, Cho NP, Glassford GN (1999) Large cell neuroendocrine carcinoma of the uterine cervix: a case report of a case with coexisting cervical intraepithelial neoplasia and human papillomavirus 16. Pathology 31:158–161CrossRefPubMed
Metadata
Title
Large cell neuroendocrine carcinoma of the uterine cervix: a report of a case and review of the literature
Authors
Yilmaz Dikmen
Mert Kazandi
Osman Zekioglu
Aydin Ozsaran
Mustafa Cosan Terek
Yildiz Erhan
Publication date
01-11-2004
Publisher
Springer-Verlag
Published in
Archives of Gynecology and Obstetrics / Issue 3/2004
Print ISSN: 0932-0067
Electronic ISSN: 1432-0711
DOI
https://doi.org/10.1007/s00404-003-0482-0

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