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Archives of Dermatological Research
Published in: Archives of Dermatological Research 2/2018

01-03-2018 | Review

Pemphigus trigger factors: special focus on pemphigus vulgaris and pemphigus foliaceus

Author: Soheil Tavakolpour

Published in: Archives of Dermatological Research | Issue 2/2018

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Abstract

Pemphigus is a general term for a rare group of autoimmune diseases which result in the formation of blisters on the skin and oral cavity. Although there is no way to prevent autoimmune diseases, some factors may trigger pemphigus initiation in susceptible individuals or be exacerbated in affected patients. Recognition of these triggers, based on the latest studies and experiences is essential and should be updated every few years. In this study, several triggers, including different drugs and treatments, diseases, vaccines, genetic factors, nutrients, micronutrients, pregnancy, stress, and various other triggers have been discussed. Some possible triggers, such as blood antigens and the effect of seasons have also been discussed briefly. Moreover, some protective factors against pemphigus have been reviewed. Considering the molecular mechanism of pemphigus and immune response alteration during this disease, some possible triggers have been suggested and discussed. Although those triggers may be a real threat, more studies are needed to support these hypotheses.
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Metadata
Title
Pemphigus trigger factors: special focus on pemphigus vulgaris and pemphigus foliaceus
Author
Soheil Tavakolpour
Publication date
01-03-2018
Publisher
Springer Berlin Heidelberg
Published in
Archives of Dermatological Research / Issue 2/2018
Print ISSN: 0340-3696
Electronic ISSN: 1432-069X
DOI
https://doi.org/10.1007/s00403-017-1790-8

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