Skip to main content
Top
Published in: Archives of Orthopaedic and Trauma Surgery 8/2019

01-08-2019 | Trauma Surgery

The influence of screw length on predicted cut-out failures for proximal humeral fracture fixations predicted by finite element simulations

Authors: James W. A. Fletcher, Markus Windolf, Leonard Grünwald, R. Geoff Richards, Boyko Gueorguiev, Peter Varga

Published in: Archives of Orthopaedic and Trauma Surgery | Issue 8/2019

Login to get access

Abstract

Background

The aim of this study was to identify the effect of screw length on predictions of fixation failure in three-part proximal humeral fractures using a finite element-based osteosynthesis modelling toolkit.

Methods

A mal-reduced unstable three-part AO/OTA 11-B3.2 fracture with medial comminution was simulated in forty-two digitally processed proximal humeri covering a spectrum of bone densities and fixed with the PHILOS plate using three distal and six proximal locking screws. Four test groups were generated based on the screw tip to joint surface distance (TJD), with all proximal screws being shortened from 4 mm TJD to be 8, 12 or 16 mm TJD. Average bone strains around the screw tips, correlating with biomechanical cyclic cut-out-type failure, were evaluated in three physiological loading protocols representing simple shoulder motions. Six further groups were tested, where five of the proximal screws were inserted to 4 mm TJD and the sixth screw to 8 mm TJD.

Results

Exponential increases in the predicted risk of fixation failure were seen with increased tip-to-joint distances (p < 0.001). When one of the proximal screws was placed 8 mm from the joint, with the remaining five at 4 mm distance, significant increases (p < 0.001) were registered in the strains around the screw tips in all except the two superior screws. This effect was maximal around the calcar screws (p < 0.001) and for lower density samples (p < 0.001).

Conclusions

These results suggest that longer screws provide reduced risk of cut-out failure, i.e. distalisation and/or varisation of the head fragment, and thus may decrease failure rates in proximal humeral fractures treated with angular stable plates. These findings require clinical corroboration and further studies to investigate the risk of screw perforation.
Literature
1.
go back to reference Brunner F, Sommer C, Bahrs C et al (2009) Open reduction and internal fixation of proximal humerus fractures using a proximal humeral locked plate: a prospective multicenter analysis. J Orthop Trauma 23(3):163–172CrossRef Brunner F, Sommer C, Bahrs C et al (2009) Open reduction and internal fixation of proximal humerus fractures using a proximal humeral locked plate: a prospective multicenter analysis. J Orthop Trauma 23(3):163–172CrossRef
2.
go back to reference Gupta AK, Harris JD, Erickson BJ et al (2015) Surgical management of complex proximal humerus fractures—a systematic review of 92 studies including 4500 patients. J Orthop Trauma 29(1):54–59CrossRefPubMed Gupta AK, Harris JD, Erickson BJ et al (2015) Surgical management of complex proximal humerus fractures—a systematic review of 92 studies including 4500 patients. J Orthop Trauma 29(1):54–59CrossRefPubMed
3.
go back to reference Schnetzke M, Bockmeyer J, Porschke F, Studier-Fischer S, Grützner P-A, Guehring T (2016) Quality of reduction influences outcome after locked-plate fixation of proximal humeral type-C fractures. JBJS 98(21):1777–1785CrossRef Schnetzke M, Bockmeyer J, Porschke F, Studier-Fischer S, Grützner P-A, Guehring T (2016) Quality of reduction influences outcome after locked-plate fixation of proximal humeral type-C fractures. JBJS 98(21):1777–1785CrossRef
4.
go back to reference Sproul RC, Iyengar JJ, Devcic Z, Feeley BT (2011) A systematic review of locking plate fixation of proximal humerus fractures. Injury 42(4):408–413CrossRefPubMed Sproul RC, Iyengar JJ, Devcic Z, Feeley BT (2011) A systematic review of locking plate fixation of proximal humerus fractures. Injury 42(4):408–413CrossRefPubMed
5.
go back to reference Beeres FJP, Hallensleben NDL, Rhemrev SJ, Goslings JC, Oehme F, Meylaerts SAG, Babst R, Schep NWL (2017) Plate fixation of the proximal humerus: an international multicentre comparative study of postoperative complications. Arch Orthop Trauma Surg 137(12):1685–1692CrossRefPubMed Beeres FJP, Hallensleben NDL, Rhemrev SJ, Goslings JC, Oehme F, Meylaerts SAG, Babst R, Schep NWL (2017) Plate fixation of the proximal humerus: an international multicentre comparative study of postoperative complications. Arch Orthop Trauma Surg 137(12):1685–1692CrossRefPubMed
6.
go back to reference Jabran A, Peach C, Ren L (2018) Biomechanical analysis of plate systems for proximal humerus fractures: a systematic literature review. Biomed Eng Online 17(1):47CrossRefPubMedPubMedCentral Jabran A, Peach C, Ren L (2018) Biomechanical analysis of plate systems for proximal humerus fractures: a systematic literature review. Biomed Eng Online 17(1):47CrossRefPubMedPubMedCentral
7.
go back to reference Gardner MJ, Weil Y, Barker JU, Kelly BT, Helfet DL, Lorich DG (2007) The importance of medial support in locked plating of proximal humerus fractures. J Orthop Trauma 21(3):185–191CrossRefPubMed Gardner MJ, Weil Y, Barker JU, Kelly BT, Helfet DL, Lorich DG (2007) The importance of medial support in locked plating of proximal humerus fractures. J Orthop Trauma 21(3):185–191CrossRefPubMed
8.
go back to reference Krappinger D, Bizzotto N, Riedmann S, Kammerlander C, Hengg C, Kralinger FS (2011) Predicting failure after surgical fixation of proximal humerus fractures. Injury 42(11):1283–1288CrossRefPubMed Krappinger D, Bizzotto N, Riedmann S, Kammerlander C, Hengg C, Kralinger FS (2011) Predicting failure after surgical fixation of proximal humerus fractures. Injury 42(11):1283–1288CrossRefPubMed
9.
go back to reference Kamer L, Noser H, Popp AW, Lenz M, Blauth M (2016) Computational anatomy of the proximal humerus: an ex vivo high-resolution peripheral quantitative computed tomography study. J Orthop Transl 4:46–56 Kamer L, Noser H, Popp AW, Lenz M, Blauth M (2016) Computational anatomy of the proximal humerus: an ex vivo high-resolution peripheral quantitative computed tomography study. J Orthop Transl 4:46–56
10.
go back to reference Liew ASL, Johnson JA, Patterson SD, King GJW, Chess DG (2000) Effect of screw placement on fixation in the humeral head. J Shoulder Elb Surg 9(5):423–426CrossRef Liew ASL, Johnson JA, Patterson SD, King GJW, Chess DG (2000) Effect of screw placement on fixation in the humeral head. J Shoulder Elb Surg 9(5):423–426CrossRef
11.
go back to reference Varga P, Grünwald L, Inzana JA, Windolf M (2017) Fatigue failure of plated osteoporotic proximal humerus fractures is predicted by the strain around the proximal screws. J Mech Behav Biomed Mater 75:68–74CrossRefPubMed Varga P, Grünwald L, Inzana JA, Windolf M (2017) Fatigue failure of plated osteoporotic proximal humerus fractures is predicted by the strain around the proximal screws. J Mech Behav Biomed Mater 75:68–74CrossRefPubMed
12.
go back to reference Varga P, Inzana JA, Gueorguiev B, Sudkamp NP, Windolf M (2018) Validated computational framework for efficient systematic evaluation of osteoporotic fracture fixation in the proximal humerus. Med Eng Phys 57:29–39CrossRefPubMed Varga P, Inzana JA, Gueorguiev B, Sudkamp NP, Windolf M (2018) Validated computational framework for efficient systematic evaluation of osteoporotic fracture fixation in the proximal humerus. Med Eng Phys 57:29–39CrossRefPubMed
13.
go back to reference Krappinger D, Roth T, Gschwentner M et al (2012) Preoperative assessment of the cancellous bone mineral density of the proximal humerus using CT data. Skelet Radiol 41(3):299–304CrossRef Krappinger D, Roth T, Gschwentner M et al (2012) Preoperative assessment of the cancellous bone mineral density of the proximal humerus using CT data. Skelet Radiol 41(3):299–304CrossRef
14.
go back to reference DePuy Synthes Trauma (2016) PHILOS and PHILOS Long. Surgical technique DePuy Synthes Trauma (2016) PHILOS and PHILOS Long. Surgical technique
15.
go back to reference Varga P, Inzana JA, Gueorguiev B, Suedkamp NP, Windolf M (2018) Validated computational framework for efficient systematic evaluation of osteoporotic fracture fixation in the proximal humerus. Med Eng Phys 57:29–39CrossRefPubMed Varga P, Inzana JA, Gueorguiev B, Suedkamp NP, Windolf M (2018) Validated computational framework for efficient systematic evaluation of osteoporotic fracture fixation in the proximal humerus. Med Eng Phys 57:29–39CrossRefPubMed
16.
go back to reference Bergmann G, Graichen F, Bender A et al (2011) In vivo gleno-humeral joint loads during forward flexion and abduction. J Biomech 44(8):1543–1552CrossRefPubMed Bergmann G, Graichen F, Bender A et al (2011) In vivo gleno-humeral joint loads during forward flexion and abduction. J Biomech 44(8):1543–1552CrossRefPubMed
17.
go back to reference Westerhoff P, Graichen F, Bender A et al (2009) In vivo measurement of shoulder joint loads during activities of daily living. J Biomech 42(12):1840–1849CrossRefPubMed Westerhoff P, Graichen F, Bender A et al (2009) In vivo measurement of shoulder joint loads during activities of daily living. J Biomech 42(12):1840–1849CrossRefPubMed
18.
go back to reference R (2013) A language and environment for statistical computing. R Foundation for Statistical Computing R: a language and environment for statistical computing. (eds) R Foundation for Statistical Computing. R Core Team, Vienna R (2013) A language and environment for statistical computing. R Foundation for Statistical Computing R: a language and environment for statistical computing. (eds) R Foundation for Statistical Computing. R Core Team, Vienna
19.
go back to reference Ponce BA, Thompson KJ, Raghava P et al (2013) The role of medial comminution and calcar restoration in varus collapse of proximal humeral fractures treated with locking plates. JBJS 95(16):e113CrossRef Ponce BA, Thompson KJ, Raghava P et al (2013) The role of medial comminution and calcar restoration in varus collapse of proximal humeral fractures treated with locking plates. JBJS 95(16):e113CrossRef
20.
go back to reference Jung W-B, Moon E-S, Kim S-K, Kovacevic D, Kim M-S (2013) Does medial support decrease major complications of unstable proximal humerus fractures treated with locking plate? BMC Musculoskelet Disord 14(1):102CrossRefPubMedPubMedCentral Jung W-B, Moon E-S, Kim S-K, Kovacevic D, Kim M-S (2013) Does medial support decrease major complications of unstable proximal humerus fractures treated with locking plate? BMC Musculoskelet Disord 14(1):102CrossRefPubMedPubMedCentral
21.
go back to reference Rangan A, Handoll H, Brealey S et al (2015) Surgical vs nonsurgical treatment of adults with displaced fractures of the proximal humerus: the PROFHER randomized clinical trial. JAMA 313(10):1037–1047CrossRef Rangan A, Handoll H, Brealey S et al (2015) Surgical vs nonsurgical treatment of adults with displaced fractures of the proximal humerus: the PROFHER randomized clinical trial. JAMA 313(10):1037–1047CrossRef
22.
go back to reference Simpson AHRW, Howie CR, Norrie J (2017) Surgical trial design—learning curve and surgeon volume. Bone Jt Res 6(4):194–195CrossRef Simpson AHRW, Howie CR, Norrie J (2017) Surgical trial design—learning curve and surgeon volume. Bone Jt Res 6(4):194–195CrossRef
23.
go back to reference Padegimas EM, Zmistowski B, Lawrence C, Palmquist A, Nicholson TA, Namdari S (2017) Defining optimal calcar screw positioning in proximal humerus fracture fixation. J Shoulder Elb Surg 26(11):1931–1937CrossRef Padegimas EM, Zmistowski B, Lawrence C, Palmquist A, Nicholson TA, Namdari S (2017) Defining optimal calcar screw positioning in proximal humerus fracture fixation. J Shoulder Elb Surg 26(11):1931–1937CrossRef
24.
go back to reference McMillan TE, Johnstone AJ (2018) Primary screw perforation or subsequent screw cut-out following proximal humerus fracture fixation using locking plates: a review of causative factors and proposed solutions. Int Orthop 42(8):1935–1942CrossRefPubMed McMillan TE, Johnstone AJ (2018) Primary screw perforation or subsequent screw cut-out following proximal humerus fracture fixation using locking plates: a review of causative factors and proposed solutions. Int Orthop 42(8):1935–1942CrossRefPubMed
25.
go back to reference Knierzinger D, Buschbaum J, Konschake M, Richards RG, Blauth M, Windolf M (2017) Ex-vivo evaluation of a novel system for implant positioning assistance at the proximal humerus using angular stable plates. Kongress Deutsche Gesellschaft für Biomechanik, Hannover Knierzinger D, Buschbaum J, Konschake M, Richards RG, Blauth M, Windolf M (2017) Ex-vivo evaluation of a novel system for implant positioning assistance at the proximal humerus using angular stable plates. Kongress Deutsche Gesellschaft für Biomechanik, Hannover
27.
go back to reference Synek A, Chevalier Y, Baumbach SF, Pahr DH (2015) The influence of bone density and anisotropy in finite element models of distal radius fracture osteosynthesis: evaluations and comparison to experiments. J Biomech 48(15):4116–4123CrossRefPubMed Synek A, Chevalier Y, Baumbach SF, Pahr DH (2015) The influence of bone density and anisotropy in finite element models of distal radius fracture osteosynthesis: evaluations and comparison to experiments. J Biomech 48(15):4116–4123CrossRefPubMed
28.
go back to reference Chen YN, Chang CW, Lin CW et al (2017) Numerical investigation of fracture impaction in proximal humeral fracture fixation with locking plate and intramedullary nail. Int Orthop 41(7):1471–1480CrossRefPubMed Chen YN, Chang CW, Lin CW et al (2017) Numerical investigation of fracture impaction in proximal humeral fracture fixation with locking plate and intramedullary nail. Int Orthop 41(7):1471–1480CrossRefPubMed
29.
go back to reference Kennedy J, Feerick E, McGarry P, FitzPatrick D, Mullett H (2013) Effect of calcium triphosphate cement on proximal humeral fracture osteosynthesis: a finite element analysis. J Orthop Surg 21(2):167–172CrossRef Kennedy J, Feerick E, McGarry P, FitzPatrick D, Mullett H (2013) Effect of calcium triphosphate cement on proximal humeral fracture osteosynthesis: a finite element analysis. J Orthop Surg 21(2):167–172CrossRef
30.
go back to reference Yang P, Zhang Y, Liu J, Xiao J, Ma LM, Zhu CR (2015) Biomechanical effect of medial cortical support and medial screw support on locking plate fixation in proximal humeral fractures with a medial gap: a finite element analysis. Acta Orthop Traumatol Turc 49:203–209PubMed Yang P, Zhang Y, Liu J, Xiao J, Ma LM, Zhu CR (2015) Biomechanical effect of medial cortical support and medial screw support on locking plate fixation in proximal humeral fractures with a medial gap: a finite element analysis. Acta Orthop Traumatol Turc 49:203–209PubMed
31.
go back to reference Diederichs G, Korner J, Goldhahn J, Linke B (2006) Assessment of bone quality in the proximal humerus by measurement of the contralateral site: a cadaveric analyze. Arch Orthop Trauma Surg 126(2):93–100CrossRefPubMed Diederichs G, Korner J, Goldhahn J, Linke B (2006) Assessment of bone quality in the proximal humerus by measurement of the contralateral site: a cadaveric analyze. Arch Orthop Trauma Surg 126(2):93–100CrossRefPubMed
32.
go back to reference Kathrein S, Kralinger F, Blauth M, Schmoelz W (2013) Biomechanical comparison of an angular stable plate with augmented and non-augmented screws in a newly developed shoulder test bench. Clin Biomech 28:273–277CrossRef Kathrein S, Kralinger F, Blauth M, Schmoelz W (2013) Biomechanical comparison of an angular stable plate with augmented and non-augmented screws in a newly developed shoulder test bench. Clin Biomech 28:273–277CrossRef
Metadata
Title
The influence of screw length on predicted cut-out failures for proximal humeral fracture fixations predicted by finite element simulations
Authors
James W. A. Fletcher
Markus Windolf
Leonard Grünwald
R. Geoff Richards
Boyko Gueorguiev
Peter Varga
Publication date
01-08-2019
Publisher
Springer Berlin Heidelberg
Published in
Archives of Orthopaedic and Trauma Surgery / Issue 8/2019
Print ISSN: 0936-8051
Electronic ISSN: 1434-3916
DOI
https://doi.org/10.1007/s00402-019-03175-x

Other articles of this Issue 8/2019

Archives of Orthopaedic and Trauma Surgery 8/2019 Go to the issue