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Published in: Archives of Orthopaedic and Trauma Surgery 1/2017

Open Access 01-01-2017 | Trauma Surgery

Do we still need autopsy in times of modern multislice computed tomography?—Missed diagnoses in the emergency room

Authors: S. A. Euler, T. Kastenberger, R. Attal, M. Rieger, M. Blauth, M. Petri

Published in: Archives of Orthopaedic and Trauma Surgery | Issue 1/2017

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Abstract

Introduction

In spite of increasing quality of emergency room (ER) assessment in trauma patients and improved accuracy of modern multislice computed tomography (MSCT), the number of potentially missed diagnoses is still controversial. The aim of this study was to compare the initial findings of ER assessment and MSCT to the findings during autopsy in trauma patients not surviving the first 48 h after admission. We hypothesized that autopsy was more accurate than MSCT in diagnosing potentially fatal diagnoses.

Patients and methods

Between January 2004 and September 2007, all trauma patients undergoing ER treatment in our institution who deceased within 48 h after admission were analyzed regarding diagnoses from initial ER assessment, including MSCT, and diagnoses from autopsy. Data were prospectively collected and retrospectively analyzed. Autopsy reports were compared to diagnoses of ER assessment and MSCT. Missed diagnoses (MD) and missed potentially fatal diagnoses (MPFD) were analyzed.

Results

Seventy-three patients with a mean age of 53.2 years were included into the study. Sixty-three percent were male. Autopsy revealed at least one missed diagnosis in 25% of the patients, with the thoracic area accounting for 67% of these. At least one MPFD was found in 4.1% of the patients, all of them being located in the thorax. Total numbers of MD and MPFD were significantly lower for the newer CT generation (64 MSCT, N = 11), compared to older one (4 MSCT, N = 26).

Conclusions

As determined by autopsy, modern multislice computed tomography is an accurate method to diagnose injuries. However, 25% of all diagnoses, and 4.1% of potentially fatal diagnoses are still missed in trauma patients, who deceased within the first 48 h after admission. Therefore, autopsy seems to be necessary to determine potentially missed diagnoses for both academic and medicolegal reasons as well as for quality control.
Literature
1.
go back to reference Huber-Wagner S, Lefering R, Qvick LM, Körner M, Kay MV, Pfeifer KJ et al. (2009) Effect of whole-body CT during trauma resuscitation on survival: a retrospective, multicentre study. Lancet 25 373(9673):1455–1461 Huber-Wagner S, Lefering R, Qvick LM, Körner M, Kay MV, Pfeifer KJ et al. (2009) Effect of whole-body CT during trauma resuscitation on survival: a retrospective, multicentre study. Lancet 25 373(9673):1455–1461
2.
go back to reference Rieger M, Czermak B, El Attal R, Sumann G, Jaschke W, Freund M (2009) Initial clinical experience with a 64-MDCT whole-body scanner in an emergency department: better time management and diagnostic quality? J Trauma 66(3):648–657CrossRefPubMed Rieger M, Czermak B, El Attal R, Sumann G, Jaschke W, Freund M (2009) Initial clinical experience with a 64-MDCT whole-body scanner in an emergency department: better time management and diagnostic quality? J Trauma 66(3):648–657CrossRefPubMed
3.
go back to reference Rieger M, Sparr H, Esterhammer R, Fink C, Bale R, Czermak B et al (2002) Modern CT diagnosis of acute thoracic and abdominal trauma. Anaesthesist 51(10):835–842 (Review. German) CrossRefPubMed Rieger M, Sparr H, Esterhammer R, Fink C, Bale R, Czermak B et al (2002) Modern CT diagnosis of acute thoracic and abdominal trauma. Anaesthesist 51(10):835–842 (Review. German) CrossRefPubMed
4.
go back to reference Barendregt WB, de Boer HH, Kubat K (1993) Quality control in fatally injured patients: the value of the necropsy. Eur J Surg 159(1):9–13PubMed Barendregt WB, de Boer HH, Kubat K (1993) Quality control in fatally injured patients: the value of the necropsy. Eur J Surg 159(1):9–13PubMed
5.
go back to reference Goldman L, Sayson R, Robbins S, Cohn LH, Bettmann M, Weisberg M (1983) The value of the autopsy in three medical eras. N Engl J Med 308(17):1000–1005CrossRefPubMed Goldman L, Sayson R, Robbins S, Cohn LH, Bettmann M, Weisberg M (1983) The value of the autopsy in three medical eras. N Engl J Med 308(17):1000–1005CrossRefPubMed
6.
go back to reference Hodgson NF, Stewart TC, Girotti MJ (2000) Autopsies and death certification in deaths due to blunt trauma: what are we missing? Can J Surg 43(2):130–136PubMedPubMedCentral Hodgson NF, Stewart TC, Girotti MJ (2000) Autopsies and death certification in deaths due to blunt trauma: what are we missing? Can J Surg 43(2):130–136PubMedPubMedCentral
7.
go back to reference Sharma BR, Gupta M, Harish D, Singh VP (2005) Missed diagnoses in trauma patients vis-a-vis significance of autopsy. Injury 36(8):976–983CrossRefPubMed Sharma BR, Gupta M, Harish D, Singh VP (2005) Missed diagnoses in trauma patients vis-a-vis significance of autopsy. Injury 36(8):976–983CrossRefPubMed
8.
go back to reference Stothert JC Jr, Gbaanador GB, Herndon DN (1990) The role of autopsy in death resulting from trauma. J Trauma 30(8):1021–1026CrossRefPubMed Stothert JC Jr, Gbaanador GB, Herndon DN (1990) The role of autopsy in death resulting from trauma. J Trauma 30(8):1021–1026CrossRefPubMed
9.
go back to reference Steinwall D, Befrits F, Naidoo SR, Hardcastle T, Eriksson A, Muckart DJ (2012) Deaths at a Level 1 Trauma Unit: a clinical finding and post-mortem correlation study. Injury 43(1):91–95CrossRefPubMed Steinwall D, Befrits F, Naidoo SR, Hardcastle T, Eriksson A, Muckart DJ (2012) Deaths at a Level 1 Trauma Unit: a clinical finding and post-mortem correlation study. Injury 43(1):91–95CrossRefPubMed
10.
go back to reference Forsythe RM, Livingston DH, Lavery RF, Mosenthal AC, Hauser CJ (2002) Autopsies in trauma do not add to peer review or quality assurance. J Trauma 53(2):321–325CrossRefPubMed Forsythe RM, Livingston DH, Lavery RF, Mosenthal AC, Hauser CJ (2002) Autopsies in trauma do not add to peer review or quality assurance. J Trauma 53(2):321–325CrossRefPubMed
11.
go back to reference Fung Kon Jin PH, Klaver JF, Maes A, Ponsen KJ, Das C, Goslings JC (2008) Autopsies following death due to traumatic injuries in The Netherlands: an evaluation of current practice. Injury 39(1):83–89CrossRefPubMed Fung Kon Jin PH, Klaver JF, Maes A, Ponsen KJ, Das C, Goslings JC (2008) Autopsies following death due to traumatic injuries in The Netherlands: an evaluation of current practice. Injury 39(1):83–89CrossRefPubMed
12.
go back to reference Ong AW, Cohn SM, Cohn KA, Jaramillo DH, Parbhu R, McKenney MG et al (2002) Unexpected findings in trauma patients dying in the intensive care unit: results of 153 consecutive autopsies. J Am Coll Surg 194(4):401–406CrossRefPubMed Ong AW, Cohn SM, Cohn KA, Jaramillo DH, Parbhu R, McKenney MG et al (2002) Unexpected findings in trauma patients dying in the intensive care unit: results of 153 consecutive autopsies. J Am Coll Surg 194(4):401–406CrossRefPubMed
13.
go back to reference Matthes G, Seifert J, Ostermann PA, Wurfel S, Ekkernkamp A, Wich M (2001) Early death of the severly injured patient—a retrospective analysis. Zentralbl Chir 126(12):995–999CrossRefPubMed Matthes G, Seifert J, Ostermann PA, Wurfel S, Ekkernkamp A, Wich M (2001) Early death of the severly injured patient—a retrospective analysis. Zentralbl Chir 126(12):995–999CrossRefPubMed
14.
go back to reference Streat SJ, Civil ID (1990) Injury scaling at autopsy: the comparison with premortem clinical data. Accid Anal Prev 22(3):241–252CrossRefPubMed Streat SJ, Civil ID (1990) Injury scaling at autopsy: the comparison with premortem clinical data. Accid Anal Prev 22(3):241–252CrossRefPubMed
15.
go back to reference Molina DK, Nichols JJ, Dimaio VJ (2007) The sensitivity of computed tomography (CT) scans in detecting trauma: are CT scans reliable enough for courtroom testimony? J Trauma 63(3):625–629CrossRefPubMed Molina DK, Nichols JJ, Dimaio VJ (2007) The sensitivity of computed tomography (CT) scans in detecting trauma: are CT scans reliable enough for courtroom testimony? J Trauma 63(3):625–629CrossRefPubMed
Metadata
Title
Do we still need autopsy in times of modern multislice computed tomography?—Missed diagnoses in the emergency room
Authors
S. A. Euler
T. Kastenberger
R. Attal
M. Rieger
M. Blauth
M. Petri
Publication date
01-01-2017
Publisher
Springer Berlin Heidelberg
Published in
Archives of Orthopaedic and Trauma Surgery / Issue 1/2017
Print ISSN: 0936-8051
Electronic ISSN: 1434-3916
DOI
https://doi.org/10.1007/s00402-016-2588-4

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