Skip to main content
Top
Published in: Archives of Orthopaedic and Trauma Surgery 5/2016

Open Access 01-05-2016 | Arthroscopy and Sports Medicine

Biomechanical effect of unloader braces for medial osteoarthritis of the knee: a systematic review (CRD 42015026136)

Authors: Wolf Petersen, Andree Ellermann, Thore Zantop, Ingo Volker Rembitzki, Hartmut Semsch, Christian Liebau, Raymond Best

Published in: Archives of Orthopaedic and Trauma Surgery | Issue 5/2016

Login to get access

Abstract

Purpose

There is a lack of consensus regarding biomechanical effects of unloader braces for the treatment of medial osteoarthritis (OA) of the knee. The purpose of this study was to perform a systematic review of studies examining the biomechanical effect of unloader braces.

Methods

A systematic search for articles about the biomechanical effect of unloader braces was performed. Primary outcome measure was the influence of the brace on the knee adduction moment. Data sources were Pubmed central and google scholar.

Results

Twenty-four articles were included. Twenty articles showed that valgus unloader braces significantly decrease the knee adduction moment. Seven of those studies reported a decrease of pain in braced patients (secondary outcome measure). Positive effects on the knee adduction moment could be found for custom made braces for conventional knee braces and for a foot ankle orthosis. Four studies could not show any effect of knee unloader braces on the knee adduction moment although one of these studies found decreased pain in braced patients. One of these studies examined healthy patients with a neutral axis.

Conclusion

This systematic review could demonstrate evidence that unloader braces reduce the adduction moment of the knee. Foresighted, a systematic review about the clinical effect of unloader braces is required.
Literature
1.
go back to reference Arazpour M, Hutchins SW, Bani MA, Curran S, Aksenov A (2014) The influence of a bespoke unloader knee brace on gait in medial compartment osteoarthritis: a pilot study. Prosthet Orthot Int 38(5):379–386CrossRefPubMed Arazpour M, Hutchins SW, Bani MA, Curran S, Aksenov A (2014) The influence of a bespoke unloader knee brace on gait in medial compartment osteoarthritis: a pilot study. Prosthet Orthot Int 38(5):379–386CrossRefPubMed
2.
go back to reference Arazpour M, Ahmadi Bani M, Hutchins SW, Jones RK, Habibi Babadi M (2013) Frontal plane corrective ability of a new unloader orthosis for medial compartment of the knee. Prosthet Orthot Int 37(6):481–488CrossRefPubMed Arazpour M, Ahmadi Bani M, Hutchins SW, Jones RK, Habibi Babadi M (2013) Frontal plane corrective ability of a new unloader orthosis for medial compartment of the knee. Prosthet Orthot Int 37(6):481–488CrossRefPubMed
3.
go back to reference Brouwer RW, van Raaij TM, Verhaar JA, Coene LN, Bierma- Zienstra SM (2006) Brace treatment for osteoarthritis of the knee: a prospective randomized multi-centre trial. Osteoarthritis Cartilage 14:777–783CrossRefPubMed Brouwer RW, van Raaij TM, Verhaar JA, Coene LN, Bierma- Zienstra SM (2006) Brace treatment for osteoarthritis of the knee: a prospective randomized multi-centre trial. Osteoarthritis Cartilage 14:777–783CrossRefPubMed
4.
go back to reference Della Croce U, Crapanzano F, Li L, Kasi PK, Patritti BL, Mancinelli C, Hunter DJ, Stamenović D, Harvey WF, Bonato P (2013) A preliminary assessment of a novel pneumatic unloading knee brace on the gait mechanics of patients with knee osteoarthritis. PM R 5(10):816–824CrossRefPubMed Della Croce U, Crapanzano F, Li L, Kasi PK, Patritti BL, Mancinelli C, Hunter DJ, Stamenović D, Harvey WF, Bonato P (2013) A preliminary assessment of a novel pneumatic unloading knee brace on the gait mechanics of patients with knee osteoarthritis. PM R 5(10):816–824CrossRefPubMed
5.
go back to reference Dessery Y, Belzile EL, Turmel S, Corbeil P (2014) Comparison of three knee braces in the treatment of medial knee osteoarthritis. Knee 21(6):1107–1114CrossRefPubMed Dessery Y, Belzile EL, Turmel S, Corbeil P (2014) Comparison of three knee braces in the treatment of medial knee osteoarthritis. Knee 21(6):1107–1114CrossRefPubMed
6.
go back to reference Draganich L, Reider B, Rimington T, Piotrowski G, Mallik K, Nasson S (2006) The effectiveness of self-adjustable custom and off-the-shelf bracing in the treatment of varus gonarthrosis. J Bone Joint Surg Am 88(12):2645–2652CrossRefPubMed Draganich L, Reider B, Rimington T, Piotrowski G, Mallik K, Nasson S (2006) The effectiveness of self-adjustable custom and off-the-shelf bracing in the treatment of varus gonarthrosis. J Bone Joint Surg Am 88(12):2645–2652CrossRefPubMed
7.
go back to reference Duivenvoorden T, van Raaij TM, Horemans HL, Brouwer RW, Bos PK, Bierma-Zeinstra SM, Verhaar JA, Reijman M (2015) Do laterally wedged insoles or valgus braces unload the medial compartment of the knee in patients with osteoarthritis? Clin Orthop Relat Res 473(1):265–274CrossRefPubMedPubMedCentral Duivenvoorden T, van Raaij TM, Horemans HL, Brouwer RW, Bos PK, Bierma-Zeinstra SM, Verhaar JA, Reijman M (2015) Do laterally wedged insoles or valgus braces unload the medial compartment of the knee in patients with osteoarthritis? Clin Orthop Relat Res 473(1):265–274CrossRefPubMedPubMedCentral
8.
go back to reference Ebert JR, Hambly K, Joss B, Ackland TR, Donnelly CJ (2014) Does an unloader brace reduce knee loading in normally aligned knees? Clin Orthop Relat Res 472(3):915–922CrossRefPubMedPubMedCentral Ebert JR, Hambly K, Joss B, Ackland TR, Donnelly CJ (2014) Does an unloader brace reduce knee loading in normally aligned knees? Clin Orthop Relat Res 472(3):915–922CrossRefPubMedPubMedCentral
9.
go back to reference Fantini Pagani CH, Potthast W, Brüggemann GP (2010) The effect of valgus bracing on the knee adduction moment during gait and running in male subjects with varus alignment. Clin Biomech (Bristol, Avon); 25(1):70–76 Fantini Pagani CH, Potthast W, Brüggemann GP (2010) The effect of valgus bracing on the knee adduction moment during gait and running in male subjects with varus alignment. Clin Biomech (Bristol, Avon); 25(1):70–76
10.
go back to reference Fantini Pagani CH, Hinrichs M, Brüggemann GP (2012) Kinetic and kinematic changes with the use of valgus knee brace and lateral wedge insoles in patients with medial knee osteoarthritis. J Orthop Res 30(7):1125–1132CrossRefPubMed Fantini Pagani CH, Hinrichs M, Brüggemann GP (2012) Kinetic and kinematic changes with the use of valgus knee brace and lateral wedge insoles in patients with medial knee osteoarthritis. J Orthop Res 30(7):1125–1132CrossRefPubMed
11.
go back to reference Fantini Pagani CH, Willwacher S, Benker R, Brüggemann GP (2014) Effect of an ankle-foot orthosis on knee joint mechanics: a novel conservative treatment for knee osteoarthritis. Prosthet Orthot Int 38(6):481–491CrossRefPubMed Fantini Pagani CH, Willwacher S, Benker R, Brüggemann GP (2014) Effect of an ankle-foot orthosis on knee joint mechanics: a novel conservative treatment for knee osteoarthritis. Prosthet Orthot Int 38(6):481–491CrossRefPubMed
12.
go back to reference Fitzgerald GK (2005) Therapeutic exercise for knee osteoarthritis: considering factors that may influence outcome. Eura Medicophys 41:163–171PubMed Fitzgerald GK (2005) Therapeutic exercise for knee osteoarthritis: considering factors that may influence outcome. Eura Medicophys 41:163–171PubMed
13.
go back to reference Fu HC, Lie CW, Ng TP, Chen KW, Tse CY, Wong WH (2015) Prospective study on the effects of orthotic treatment for medial knee osteoarthritis in Chinese patients: clinical outcome and gait analysis. Hong Kong Med J 21(2):98–106PubMed Fu HC, Lie CW, Ng TP, Chen KW, Tse CY, Wong WH (2015) Prospective study on the effects of orthotic treatment for medial knee osteoarthritis in Chinese patients: clinical outcome and gait analysis. Hong Kong Med J 21(2):98–106PubMed
14.
go back to reference Gaasbeek RD, Groen BE, Hampsink B, van Heerwaarden RJ, Duysens J (2007) Valgus bracing in patients with medial compartment osteoarthritis of the knee. A gait analysis study of a new brace. Gait Posture 26(1):3–10 Gaasbeek RD, Groen BE, Hampsink B, van Heerwaarden RJ, Duysens J (2007) Valgus bracing in patients with medial compartment osteoarthritis of the knee. A gait analysis study of a new brace. Gait Posture 26(1):3–10
15.
go back to reference Harris JD, Quatman CE, Manring MM, Siston RA, Flanigan DC (2014) How to write a systematic review. Am J Sports Med 42(11):2761–2768CrossRefPubMed Harris JD, Quatman CE, Manring MM, Siston RA, Flanigan DC (2014) How to write a systematic review. Am J Sports Med 42(11):2761–2768CrossRefPubMed
16.
go back to reference Hewett TE, Noyes FR, Barber-Westin SD, Heckmann TP (1998) Decrease in knee joint pain and increase in function in patients with medial compartment arthrosis: a prospective analysis of valgus bracing. Orthopedics 21(2):131–138PubMed Hewett TE, Noyes FR, Barber-Westin SD, Heckmann TP (1998) Decrease in knee joint pain and increase in function in patients with medial compartment arthrosis: a prospective analysis of valgus bracing. Orthopedics 21(2):131–138PubMed
17.
go back to reference Horlick SG, Loomer RL (1993) Valgus knee bracing for medial gonarthrosis. Clin Sport Med 3:251–255CrossRef Horlick SG, Loomer RL (1993) Valgus knee bracing for medial gonarthrosis. Clin Sport Med 3:251–255CrossRef
18.
go back to reference Johnson AJ, Starr R, Kapadia BH, Bhave A, Mont MA (2013) Gait and clinical improvements with a novel knee brace for knee OA. J Knee Surg 26(3):173–178CrossRefPubMed Johnson AJ, Starr R, Kapadia BH, Bhave A, Mont MA (2013) Gait and clinical improvements with a novel knee brace for knee OA. J Knee Surg 26(3):173–178CrossRefPubMed
19.
go back to reference Jones RK, Nester CJ, Richards JD, Kim WY, Johnson DS, Jari S, Laxton P, Tyson SF (2013) A comparison of the biomechanical effects of valgus knee braces and lateral wedged insoles in patients with knee osteoarthritis. Gait Posture 37(3):368–372CrossRefPubMed Jones RK, Nester CJ, Richards JD, Kim WY, Johnson DS, Jari S, Laxton P, Tyson SF (2013) A comparison of the biomechanical effects of valgus knee braces and lateral wedged insoles in patients with knee osteoarthritis. Gait Posture 37(3):368–372CrossRefPubMed
20.
go back to reference Kemp G, Crossley KM, Wrigley TV, Metcalf BR, Hinman RS (2008) Reducing joint loading in medial knee osteoarthritis: shoes and canes. Arthritis Rheum 59(5):609–614CrossRefPubMed Kemp G, Crossley KM, Wrigley TV, Metcalf BR, Hinman RS (2008) Reducing joint loading in medial knee osteoarthritis: shoes and canes. Arthritis Rheum 59(5):609–614CrossRefPubMed
21.
go back to reference Komistek RD, Dennis DA, Northcut EJ, Wood A, Parker AW, Traina SM (1999) An in vivo analysis of the effectiveness of the osteoarthritic knee brace during heel-strike of gait. J Arthroplasty 14(6):738–742CrossRefPubMed Komistek RD, Dennis DA, Northcut EJ, Wood A, Parker AW, Traina SM (1999) An in vivo analysis of the effectiveness of the osteoarthritic knee brace during heel-strike of gait. J Arthroplasty 14(6):738–742CrossRefPubMed
22.
go back to reference Kutzner I, Küther S, Heinlein B, Dymke J, Bender A, Halder AM, Bergmann G (2011) The effect of valgus braces on medial compartment load of the knee joint—in vivo load measurements in three subjects. J Biomech 44(7):1354–1360CrossRefPubMed Kutzner I, Küther S, Heinlein B, Dymke J, Bender A, Halder AM, Bergmann G (2011) The effect of valgus braces on medial compartment load of the knee joint—in vivo load measurements in three subjects. J Biomech 44(7):1354–1360CrossRefPubMed
23.
go back to reference Lamberg EM, Streb R, Werner M, Kremenic I, Penna J (2015) The 2- and 8-week effects of decompressive brace use in people with medial compartment knee osteoarthritis. Prosthet Orthot Int. pii: 0309364615589537 (Epub ahead of print) Lamberg EM, Streb R, Werner M, Kremenic I, Penna J (2015) The 2- and 8-week effects of decompressive brace use in people with medial compartment knee osteoarthritis. Prosthet Orthot Int. pii: 0309364615589537 (Epub ahead of print)
24.
go back to reference Laroche D, Morisset C, Fortunet C, Gremeaux V, Maillefert JF, Ornetti P (2014) Biomechanical effectiveness of a distraction-rotation knee brace in medial knee osteoarthritis: preliminary results. Knee. 21(3):710–716CrossRefPubMed Laroche D, Morisset C, Fortunet C, Gremeaux V, Maillefert JF, Ornetti P (2014) Biomechanical effectiveness of a distraction-rotation knee brace in medial knee osteoarthritis: preliminary results. Knee. 21(3):710–716CrossRefPubMed
25.
go back to reference Lewek MD, Rudolph KS, Snyder-Mackler L (2004) Control of frontal plane knee laxity during gait in patients with medial compartment knee osteoarthritis. Osteoarthritis Cartilage 12:745–751CrossRefPubMedPubMedCentral Lewek MD, Rudolph KS, Snyder-Mackler L (2004) Control of frontal plane knee laxity during gait in patients with medial compartment knee osteoarthritis. Osteoarthritis Cartilage 12:745–751CrossRefPubMedPubMedCentral
26.
go back to reference Lindenfeld TN, Hewett TE, Andriacchi TP (1997) Joint loading with valgus bracing in patients with varus gonarthrosis. Clin Orthop Relat Res 344:290–297CrossRefPubMed Lindenfeld TN, Hewett TE, Andriacchi TP (1997) Joint loading with valgus bracing in patients with varus gonarthrosis. Clin Orthop Relat Res 344:290–297CrossRefPubMed
27.
go back to reference McAlindon TE, Bannuru RR, Sullivan MC, Arden NK, Berenbaum F, Bierma-Zeinstra SM, Hawker GA, Henrotin Y, Hunter DJ, Kawaguchi H, Kwoh K, Lohmander S, Rannou F, Roos EM, Underwood M (2014) OARSI guidelines for the non-surgical management of knee osteoarthritis. Osteoarthritis Cartilage 22(3):363–388CrossRefPubMed McAlindon TE, Bannuru RR, Sullivan MC, Arden NK, Berenbaum F, Bierma-Zeinstra SM, Hawker GA, Henrotin Y, Hunter DJ, Kawaguchi H, Kwoh K, Lohmander S, Rannou F, Roos EM, Underwood M (2014) OARSI guidelines for the non-surgical management of knee osteoarthritis. Osteoarthritis Cartilage 22(3):363–388CrossRefPubMed
28.
go back to reference Moher D, The PRISMA Group et al (2010) Preferred reporting items for systematic reviews and meta-analyses: the PRISMA statement. Int J Surg 8(5):336–341CrossRefPubMed Moher D, The PRISMA Group et al (2010) Preferred reporting items for systematic reviews and meta-analyses: the PRISMA statement. Int J Surg 8(5):336–341CrossRefPubMed
29.
go back to reference Moyer RF, Birmingham TB, Dombroski CE, Walsh RF, Leitch KM, Jenkyn TR, Giffin JR (2013) Combined effects of a valgus knee brace and lateral wedge foot orthotic on the external knee adduction moment in patients with varus gonarthrosis. Arch Phys Med Rehabil 94(1):103–112CrossRefPubMed Moyer RF, Birmingham TB, Dombroski CE, Walsh RF, Leitch KM, Jenkyn TR, Giffin JR (2013) Combined effects of a valgus knee brace and lateral wedge foot orthotic on the external knee adduction moment in patients with varus gonarthrosis. Arch Phys Med Rehabil 94(1):103–112CrossRefPubMed
30.
go back to reference Orishimo KF, Kremenic IJ, Lee SJ, McHugh MP, Nicholas SJ (2013) Is valgus unloader bracing effective in normally aligned individuals: implications for post-surgical protocols following cartilage restoration procedures. Knee Surg Sports Traumatol Arthrosc 21(12):2661–2666CrossRefPubMed Orishimo KF, Kremenic IJ, Lee SJ, McHugh MP, Nicholas SJ (2013) Is valgus unloader bracing effective in normally aligned individuals: implications for post-surgical protocols following cartilage restoration procedures. Knee Surg Sports Traumatol Arthrosc 21(12):2661–2666CrossRefPubMed
31.
go back to reference Ota S, Kanai A, Torii Y, Taniyama H, Imaizumi F, Matsui Y (2015) Effects of a custom-made hinged knee brace with knee flexion support for patients with knee osteoarthritis:a preliminary study. Nagoya J Med Sci 77(1–2):95–101PubMedPubMedCentral Ota S, Kanai A, Torii Y, Taniyama H, Imaizumi F, Matsui Y (2015) Effects of a custom-made hinged knee brace with knee flexion support for patients with knee osteoarthritis:a preliminary study. Nagoya J Med Sci 77(1–2):95–101PubMedPubMedCentral
32.
go back to reference Pollo FE, Otis JC, Backus SI, Warren RF, Wickiewicz TL (2002) Reduction of medial compartment loads with valgus bracing of the osteoarthritic knee. Am J Sports Med 30(3):414–421PubMed Pollo FE, Otis JC, Backus SI, Warren RF, Wickiewicz TL (2002) Reduction of medial compartment loads with valgus bracing of the osteoarthritic knee. Am J Sports Med 30(3):414–421PubMed
33.
go back to reference Ramsey DK, Russell ME (2009) Unloader braces for medial compartment knee osteoarthritis: implications on mediating progression. Sports Health 8:416–426CrossRef Ramsey DK, Russell ME (2009) Unloader braces for medial compartment knee osteoarthritis: implications on mediating progression. Sports Health 8:416–426CrossRef
34.
go back to reference Ramsey DK, Briem K, Axe MJ, Snyder-Mackler L (2007) A mechanical theory for the effectiveness of bracing for medial compartment osteoarthritis of the knee. J Bone Joint Surg Am 89(11):2398–2407CrossRefPubMedPubMedCentral Ramsey DK, Briem K, Axe MJ, Snyder-Mackler L (2007) A mechanical theory for the effectiveness of bracing for medial compartment osteoarthritis of the knee. J Bone Joint Surg Am 89(11):2398–2407CrossRefPubMedPubMedCentral
35.
go back to reference Self BP, Greenwald RM, Pflaster DS (2000) A biomechanical analysis of a medial unloading brace for osteoarthritis in the knee. Arthritis Care Res 13(4):191–197CrossRefPubMed Self BP, Greenwald RM, Pflaster DS (2000) A biomechanical analysis of a medial unloading brace for osteoarthritis in the knee. Arthritis Care Res 13(4):191–197CrossRefPubMed
36.
go back to reference Schmalz T, Knopf E, Drewitz H, Blumentritt S (2010) Analysis of biomechanical effectiveness of valgus-inducing knee brace for osteoarthritis of knee. J Rehabil Res 47(5):419–429 Schmalz T, Knopf E, Drewitz H, Blumentritt S (2010) Analysis of biomechanical effectiveness of valgus-inducing knee brace for osteoarthritis of knee. J Rehabil Res 47(5):419–429
37.
go back to reference Sharma L, Lou C, Felson DT, Dunlop DD, Kirwan-Mellis G, Hayes KW, Weinrach D, Buchanan TS (1999) Laxity in healthy and osteoarthritic knees. Arthritis Rheum 42:861–870CrossRefPubMed Sharma L, Lou C, Felson DT, Dunlop DD, Kirwan-Mellis G, Hayes KW, Weinrach D, Buchanan TS (1999) Laxity in healthy and osteoarthritic knees. Arthritis Rheum 42:861–870CrossRefPubMed
38.
go back to reference Sharma L, Song J, Felson DT, Cahue S, Shamiyeh E, Dunlop DD (2001) The role of knee alignment in disease progression and functional decline in knee osteoarthritis. JAMA 286:188–195CrossRefPubMed Sharma L, Song J, Felson DT, Cahue S, Shamiyeh E, Dunlop DD (2001) The role of knee alignment in disease progression and functional decline in knee osteoarthritis. JAMA 286:188–195CrossRefPubMed
39.
go back to reference Squyer E, Stamper DL, Hamilton DT, Sabin JA, Leopold SS (2013) Unloader knee braces for osteoarthritis: do patients actually wear them? Clin Orthop Relat Res 471(6):1982–1991CrossRefPubMedPubMedCentral Squyer E, Stamper DL, Hamilton DT, Sabin JA, Leopold SS (2013) Unloader knee braces for osteoarthritis: do patients actually wear them? Clin Orthop Relat Res 471(6):1982–1991CrossRefPubMedPubMedCentral
40.
go back to reference van Raaij TM, Reijman M, Brouwer RW, Bierma-Zeinstra SM, Verhaar JA (2010) Medial knee osteoarthritis treated by insoles or braces: a randomized trial. Clin Orthop Relat Res 468(7):1926–1932CrossRefPubMedPubMedCentral van Raaij TM, Reijman M, Brouwer RW, Bierma-Zeinstra SM, Verhaar JA (2010) Medial knee osteoarthritis treated by insoles or braces: a randomized trial. Clin Orthop Relat Res 468(7):1926–1932CrossRefPubMedPubMedCentral
Metadata
Title
Biomechanical effect of unloader braces for medial osteoarthritis of the knee: a systematic review (CRD 42015026136)
Authors
Wolf Petersen
Andree Ellermann
Thore Zantop
Ingo Volker Rembitzki
Hartmut Semsch
Christian Liebau
Raymond Best
Publication date
01-05-2016
Publisher
Springer Berlin Heidelberg
Published in
Archives of Orthopaedic and Trauma Surgery / Issue 5/2016
Print ISSN: 0936-8051
Electronic ISSN: 1434-3916
DOI
https://doi.org/10.1007/s00402-015-2388-2

Other articles of this Issue 5/2016

Archives of Orthopaedic and Trauma Surgery 5/2016 Go to the issue