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Archives of Orthopaedic and Trauma Surgery

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01-03-2010 | Orthopaedic Surgery

The effect of intraarticular combinations of tramadol and ropivacaine with ketamine on postoperative pain after arthroscopic meniscectomy

Authors: Hilal Ayoglu, Hanife Altunkaya, Ahmet Bayar, Isil Ozkocak Turan, Yetkin Ozer, Ahmet Ege

Published in: Archives of Orthopaedic and Trauma Surgery | Issue 3/2010

Abstract

Introduction

The purpose of this prospective randomized study was to evaluate the effects of intraarticular combinations of tramadol and ropivacaine with ketamine in postoperative pain control of patients undergoing arthroscopic meniscectomy.

Materials and methods

We randomly divided 80 patients into four groups to receive intraarticular 50 mg tramadol (Group T), 50 mg tramadol with 0.5 mg kg⁻¹ ketamine (Group TK), 75 mg ropivacaine (Group R), 75 mg ropivacaine with 0.5 mg kg⁻¹ ketamine (Group RK) in 20 ml normal saline at the end of surgery. Postoperative analgesia was provided with patient-controlled analgesia with morphine. Postoperative pain scores, total morphine consumption amount and side effects were recorded at intervals of 0, 1, 2, 4, 8, 12 and 24 h after the operation.

Results

Pain scores were higher in Group T when compared with Group R and Group RK at second and fourth hours, also compared with Group RK at zeroth, first, second, fourth and eighth hours. Total morphine consumption amount was found to be higher in Group T when compared to Group TK at eighth and twelfth hours and Group RK at eighth hours (P < 0.05). Total morphine consumption was lowest in Group TK (P < 0.05). There were no significant differences among the study groups regarding side effects.

Conclusions

Administration of intraarticular tramadol–ketamine combination was found to be more effective in decreasing postoperative daily analgesic consumption.

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Title: The effect of intraarticular combinations of tramadol and ropivacaine with ketamine on postoperative pain after arthroscopic meniscectomy
Authors: Hilal Ayoglu
Hanife Altunkaya
Ahmet Bayar
Isil Ozkocak Turan
Yetkin Ozer
Ahmet Ege
Publication date: 01-03-2010
Publisher: Springer-Verlag
Published in: Archives of Orthopaedic and Trauma Surgery / Issue 3/2010
Print ISSN: 0936-8051
Electronic ISSN: 1434-3916
DOI: https://doi.org/10.1007/s00402-008-0770-z

At a glance: The STEP trials

Springer Medicine

The effect of intraarticular combinations of tramadol and ropivacaine with ketamine on postoperative pain after arthroscopic meniscectomy

Abstract

Introduction

Materials and methods

Results

Conclusions

At a glance: The STEP trials

Springer Medicine

Abstract

Introduction

Materials and methods

Results

Conclusions

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