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Published in: Archives of Orthopaedic and Trauma Surgery 1/2005

01-02-2005 | Original Article

Iatrogenic paraplegia in spinal surgery

Authors: K.-S. Delank, H. W. Delank, D. P. König, F. Popken, S. Fürderer, P. Eysel

Published in: Archives of Orthopaedic and Trauma Surgery | Issue 1/2005

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Abstract

Introduction

Paraplegia as a result of a surgical spinal procedure is a rare complication. The risk cannot be precisely quantified due to the lack of current data. The aim of this study was to record a sufficiently large number of major spinal operations, especially extended methods in scoliosis surgery. Hereby, a reliable statement regarding the risk of severe neurological complications with these surgical techniques should be possible. First, a retrospective analysis of patients from a German spine centre (spinal fusion) and a survey of 17 German centres of spinal surgery were conducted for the retrospective acquisition of severe iatrogenic neurological complications.

Materials and methods

The study included 1194 patients who underwent a spinal fusion during the period 1992–2002. The incidents of postoperative paraplegia are described in detail, and case studies done. Possible causes, methods of intraoperative monitoring and options of therapy are discussed according to research in relevant publications. Additionally, severe neurological complications of 3115 spinal operations were recorded in a standardised survey conducted throughout major German spinal centres.

Results

Of the 1194 patients surveyed, 7 (0.59%) experienced a postsurgical complete or incomplete paraplegia. In 3 of the recorded cases, the cause could be identified. The survey of 3115 scoliosis surgeries showed that iatrogenic paraplegia occurred with a frequency of 0.55%. The risks associated with short spinal fusions (0.14%), cervical discectomies (0.07%) and lumbar discectomies (0.03%) are considerably less.

Conclusion

Operative treatment of scoliosis with a high degree of correction carries a risk of neurological complications of about 0.5%. Mechanical as well as ischaemic damage to the spinal cord can be detected early by means of consistent intraoperative neuromonitoring.
Literature
1.
go back to reference Bacher T, Schiltenwolf M, Niethard FU et al (1999) The risk of paraplegia through medical treatment. Spinal Cord 37:172–182 Bacher T, Schiltenwolf M, Niethard FU et al (1999) The risk of paraplegia through medical treatment. Spinal Cord 37:172–182
2.
go back to reference Bracken MB, Collins WF, Freemann DF et al (1984) Efficacy of methylprednisolone in acute spinal cord injury. JAMA 251:45–52CrossRefPubMed Bracken MB, Collins WF, Freemann DF et al (1984) Efficacy of methylprednisolone in acute spinal cord injury. JAMA 251:45–52CrossRefPubMed
3.
go back to reference Bracken MB, Shepard MJ, Collins WF et al (1990) A randomised, controlled trial of methylprednisolone or naloxone in the treatment of acute spinal-cord injury. Results of the second national acute spinal cord injury study. N Engl J Med 322:1405–1411PubMed Bracken MB, Shepard MJ, Collins WF et al (1990) A randomised, controlled trial of methylprednisolone or naloxone in the treatment of acute spinal-cord injury. Results of the second national acute spinal cord injury study. N Engl J Med 322:1405–1411PubMed
4.
go back to reference Bracken MB, Shepard MJ, Collins WF et al (1992) Methylprednisolone or naloxone treatment after acute spinal cord injury: 1-year follow-up data. J Neurosurg 76:23–31PubMed Bracken MB, Shepard MJ, Collins WF et al (1992) Methylprednisolone or naloxone treatment after acute spinal cord injury: 1-year follow-up data. J Neurosurg 76:23–31PubMed
5.
go back to reference Cabana F, Pointillart V, Vital J et al (2000) Postoperative compressive spinal epidural hematomas. 15 cases and a review of the literature. Rev Chir Orthop Rep Appar Mot 86:335–345 Cabana F, Pointillart V, Vital J et al (2000) Postoperative compressive spinal epidural hematomas. 15 cases and a review of the literature. Rev Chir Orthop Rep Appar Mot 86:335–345
6.
go back to reference Edwards CC, Heller JG, Murakami H (2002) Corporectomy versus laminoplasty for multilevel cervical myelopathy. An independent matched-cohort analysis. Spine 27:1168–1175CrossRefPubMed Edwards CC, Heller JG, Murakami H (2002) Corporectomy versus laminoplasty for multilevel cervical myelopathy. An independent matched-cohort analysis. Spine 27:1168–1175CrossRefPubMed
7.
go back to reference Faciszewski T, Winter RB et al (1995) The surgical and medical perioperative complications of anterior spinal fusion surgery in the thoracic and lumbar spine in adults. A review of 1223 procedures. Spine 20:1592–1599PubMed Faciszewski T, Winter RB et al (1995) The surgical and medical perioperative complications of anterior spinal fusion surgery in the thoracic and lumbar spine in adults. A review of 1223 procedures. Spine 20:1592–1599PubMed
8.
go back to reference George ER, Scholten DJ, Buechler CM et al (1995) Failure of methylprednisolone to improve the outcome of spinal cord injuries. Am Surg 61:659–664PubMed George ER, Scholten DJ, Buechler CM et al (1995) Failure of methylprednisolone to improve the outcome of spinal cord injuries. Am Surg 61:659–664PubMed
9.
go back to reference Kou J, Fischgrund J, Biddinger A et al (2002) Risk factors for spinal epidural hematoma after spinal surgery. Spine 27:1670–1673CrossRefPubMed Kou J, Fischgrund J, Biddinger A et al (2002) Risk factors for spinal epidural hematoma after spinal surgery. Spine 27:1670–1673CrossRefPubMed
10.
go back to reference Legos JJ, Gopez JJ, Young WF (2002) Non-surgical management of spinal cord injury. Expert Opin Investig Drugs 11:469–482PubMed Legos JJ, Gopez JJ, Young WF (2002) Non-surgical management of spinal cord injury. Expert Opin Investig Drugs 11:469–482PubMed
11.
go back to reference Lonstein JE, Winter RB, Moe JH, Bradford S,Chou SN, Pinto WC (1980) Neurologic deficits. Secondary to spinal deformity. A review of the literature and report of 43 cases. Spine 5:4PubMed Lonstein JE, Winter RB, Moe JH, Bradford S,Chou SN, Pinto WC (1980) Neurologic deficits. Secondary to spinal deformity. A review of the literature and report of 43 cases. Spine 5:4PubMed
12.
go back to reference Mayr MT, Subach BR, Comey CH et al (2002) Cervical spinal stenosis: outcome after anterior corporectomy, allograft reconstruction, and instrumentation. J Neurosurg 96 [Supp1]:10–16 Mayr MT, Subach BR, Comey CH et al (2002) Cervical spinal stenosis: outcome after anterior corporectomy, allograft reconstruction, and instrumentation. J Neurosurg 96 [Supp1]:10–16
13.
go back to reference McEwen GD, Bunnell WP, Sriram K (1975) Acute neurological complications in treatment of scoliosis. A report of the scoliosis research society. J Bone Joint Surg Am 57:404–408PubMed McEwen GD, Bunnell WP, Sriram K (1975) Acute neurological complications in treatment of scoliosis. A report of the scoliosis research society. J Bone Joint Surg Am 57:404–408PubMed
14.
go back to reference McMaster MJ, Singh H (1999) Natural history of congenital kyphosis and kyphoscoliosis. A study of one hundred and twelve patients. J Bone Joint Surg Am 81:1367–1383PubMed McMaster MJ, Singh H (1999) Natural history of congenital kyphosis and kyphoscoliosis. A study of one hundred and twelve patients. J Bone Joint Surg Am 81:1367–1383PubMed
15.
go back to reference Meinecke FW (1988) Rückenmarksschäden im Gefolge von Diagnostik und Therapie. Unfallchirurg 91:270–277PubMed Meinecke FW (1988) Rückenmarksschäden im Gefolge von Diagnostik und Therapie. Unfallchirurg 91:270–277PubMed
16.
go back to reference Metz-Stavenhagen P, Krebs S, Völpel HJ (2001) Operationsmethoden zur Behandlung der Totalkyphose bei der Spondylitis ankylosans. Orthopäde 30:988–995 Metz-Stavenhagen P, Krebs S, Völpel HJ (2001) Operationsmethoden zur Behandlung der Totalkyphose bei der Spondylitis ankylosans. Orthopäde 30:988–995
17.
go back to reference Otani K, Abe H, Kadoya S et al (1994) Beneficial effect of methylprednisolone sodium succinate in the treatment of acute spinal cord injury. Sekirsu Sekizui 7:633–647 Otani K, Abe H, Kadoya S et al (1994) Beneficial effect of methylprednisolone sodium succinate in the treatment of acute spinal cord injury. Sekirsu Sekizui 7:633–647
18.
go back to reference Pascal-Moussellard H, Broc G, Pointillart V et al (1998) Complications of vertebral metastasis surgery. Eur Spine J 7:438–444CrossRefPubMed Pascal-Moussellard H, Broc G, Pointillart V et al (1998) Complications of vertebral metastasis surgery. Eur Spine J 7:438–444CrossRefPubMed
19.
go back to reference Pointillart V, Petitjean ME, Wiart L et al (2000) Pharmacological therapy of spinal cord injury during the acute phase. Spinal Cord 38:71–76 Pointillart V, Petitjean ME, Wiart L et al (2000) Pharmacological therapy of spinal cord injury during the acute phase. Spinal Cord 38:71–76
20.
go back to reference Poynton AR, O’Farell DA, Shannon F et al (1997) An evaluation of the factors affecting neurological recovery following spinal cord injury. Injury 28:545–548CrossRefPubMed Poynton AR, O’Farell DA, Shannon F et al (1997) An evaluation of the factors affecting neurological recovery following spinal cord injury. Injury 28:545–548CrossRefPubMed
21.
go back to reference Takahashi S, Delecrin J, Passuti N (2001) Intraspinal metallosis causing delayed neurologic symptoms after spinal instrumentation surgery. Spine 26:1495–1498CrossRefPubMed Takahashi S, Delecrin J, Passuti N (2001) Intraspinal metallosis causing delayed neurologic symptoms after spinal instrumentation surgery. Spine 26:1495–1498CrossRefPubMed
22.
go back to reference Wada E, Suzuki S, Kanazawa A et al (2001) Subtotal corporectomy versus laminoplasty for multilevel cervical spondylotic myelopathy. A long-term follow-up study over 10 years. Spine 26:1443–1448CrossRefPubMed Wada E, Suzuki S, Kanazawa A et al (2001) Subtotal corporectomy versus laminoplasty for multilevel cervical spondylotic myelopathy. A long-term follow-up study over 10 years. Spine 26:1443–1448CrossRefPubMed
23.
go back to reference Wilkins C, McEwen GD (1977) Cranial nerve injury from halo traction. Clin Orthop 126:106–110PubMed Wilkins C, McEwen GD (1977) Cranial nerve injury from halo traction. Clin Orthop 126:106–110PubMed
24.
go back to reference Winter RB, Moe JH, Lonstein JE (1985) The surgical treatment of congenital kyphosis. A review of 94 patients age 5 years or older, with 2 years or more follow-up in 77 patients. Spine 10:224–231 Winter RB, Moe JH, Lonstein JE (1985) The surgical treatment of congenital kyphosis. A review of 94 patients age 5 years or older, with 2 years or more follow-up in 77 patients. Spine 10:224–231
25.
go back to reference Wise JJ, Fischgrund JS, Herkowitz HN et al (1999) Complication, survival rates, and risk factors of surgery for metastatic disease of the spine. Spine 15:1943–1951CrossRef Wise JJ, Fischgrund JS, Herkowitz HN et al (1999) Complication, survival rates, and risk factors of surgery for metastatic disease of the spine. Spine 15:1943–1951CrossRef
26.
go back to reference Zielke K, Pellin B (1975) Das neurologische Risiko der Harrington-Operation. Arch Orthop Unfall Chir 83:311–322 Zielke K, Pellin B (1975) Das neurologische Risiko der Harrington-Operation. Arch Orthop Unfall Chir 83:311–322
Metadata
Title
Iatrogenic paraplegia in spinal surgery
Authors
K.-S. Delank
H. W. Delank
D. P. König
F. Popken
S. Fürderer
P. Eysel
Publication date
01-02-2005
Publisher
Springer-Verlag
Published in
Archives of Orthopaedic and Trauma Surgery / Issue 1/2005
Print ISSN: 0936-8051
Electronic ISSN: 1434-3916
DOI
https://doi.org/10.1007/s00402-004-0763-5

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