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International Journal of Colorectal Disease

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01-03-2021 | Foreign Body Aspiration | Original Article

Needle aspiration treatment vs. incision of acute simple perianal abscess: randomized controlled study

Authors: Karam Matlub Sørensen, Sören Möller, Niels Qvist

Published in: International Journal of Colorectal Disease | Issue 3/2021

Abstract

Purpose

Needle aspiration of an acute simple perianal abscess may be an alternative to conventional incision drainage with potential advantages in wound healing, functional outcome, and quality of life. The aim and objectives of the study are to compare the outcome of needle aspiration and postoperative antibiotics with that of conventional surgical incision drainage of acute perianal abscess. The primary outcome was abscess recurrence. Secondary outcomes were fistula formation, wound healing, quality of life, and fecal continence.

Methods

This is a three-center randomized controlled trial, including adults with acute perianal abscess. The needle aspiration group received clindamycin for one week postoperatively. All included patients were scheduled for a follow-up at 2, 12, and 52 weeks postoperatively including physical examination, quality of life assessment (SF 36 questionnaire), and fecal continence (Wexner score).

Results

A total of 98 patients were included. The recurrence rate was 41% in needle aspiration and 15% in incision drainage, with HR of 3.033 (p = 0.014). Fistula formation was 15% without significant difference between the groups. There was no significant difference in wound healing, quality of life, or fecal incontinence scores.

Conclusion

Needle aspiration with postoperative antibiotics cannot be recommended as an alternative for surgical incision in the treatment of acute perianal abscess.

Trial registration number

ClinicalTrials.org with identification number NCT02585141, initial release on 15 October 2015.

RedCap (Research Electronic Data Capture) is a secure, web-based software platform designed to support data capture for research studies, providing (1) an intuitive interface for validated data capture, (2) audit trails for tracking data manipulation and export procedures, (3) automated export procedures for seamless data downloads to common statistical packages, and (4) procedures for data integration and interoperability with external sources.

Unit alcohol = 12 g alcohol. Seven units for females and 14 units for males per week according to Danish health administration recommendation for alcohol consumption

Variables with a cursive style were analyzed as both continuous and categorical variables.

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Title: Needle aspiration treatment vs. incision of acute simple perianal abscess: randomized controlled study
Authors: Karam Matlub Sørensen
Sören Möller
Niels Qvist
Publication date: 01-03-2021
Publisher: Springer Berlin Heidelberg
Keywords: Foreign Body Aspiration
Antibiotic
Foreign Body Aspiration
Aspiration
Fecal Incontinence
Incision
Published in: International Journal of Colorectal Disease / Issue 3/2021
Print ISSN: 0179-1958
Electronic ISSN: 1432-1262
DOI: https://doi.org/10.1007/s00384-021-03845-6

At a glance: The ONWARDS insulin icodec trials

Springer Medicine

Needle aspiration treatment vs. incision of acute simple perianal abscess: randomized controlled study

Abstract

Purpose

Methods

Results

Conclusion

Trial registration number

At a glance: The ONWARDS insulin icodec trials

Springer Medicine

Abstract

Purpose

Methods

Results

Conclusion

Trial registration number

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