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International Journal of Colorectal Disease

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Open Access 01-01-2021 | Wound Dehiscence | Review

The role of perineal application of prophylactic negative-pressure wound therapy for prevention of wound-related complications after abdomino-perineal resection: a systematic review

Authors: Jeremy Meyer, Elin Roos, Ziad Abbassi, Christian Toso, Frédéric Ris, Nicolas C. Buchs

Published in: International Journal of Colorectal Disease | Issue 1/2021

Abstract

Background

Closed perineal wounds often fail to heal by primary intention after abdomino-perineal resection (APR) and are often complicated by surgical site infection (SSI) and/or wound dehiscence. Recent evidence showed encouraging results of prophylactic negative-pressure wound therapy (pNPWT) for prevention of wound-related complications in surgery. Our objective was to gather and discuss the early existing literature regarding the use of pNPWT to prevent wound-related complications on perineal wounds after APR.

Methods

Medline, Embase, and Web of Science were searched for original publications and congress abstracts reporting the use of pNPWT after APR on closed perineal wounds.

Results

Seven publications were included for analysis. Two publications reported significantly lower incidence of SSI in pNPWT patients than in controls with a risk reduction of about 25–30%. Two other publications described similar incidences of SSI between the two groups of patients but described SSI in pNPWT patients to be less severe. One study reported significantly lower incidence of wound dehiscence in pNPWT patients than in controls.

Conclusion

The largest non-randomized studies investigating the effect of pNPWT on the prevention of wound-related complications after APR showed encouraging results in terms of reduction of SSI and wound dehiscence that deserve further investigation and confirmation.

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Title: The role of perineal application of prophylactic negative-pressure wound therapy for prevention of wound-related complications after abdomino-perineal resection: a systematic review
Authors: Jeremy Meyer
Elin Roos
Ziad Abbassi
Christian Toso
Frédéric Ris
Nicolas C. Buchs
Publication date: 01-01-2021
Publisher: Springer Berlin Heidelberg
Keywords: Wound Dehiscence
Rectal Cancer
Rectal Cancer
Wound Management
Published in: International Journal of Colorectal Disease / Issue 1/2021
Print ISSN: 0179-1958
Electronic ISSN: 1432-1262
DOI: https://doi.org/10.1007/s00384-020-03732-6

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The role of perineal application of prophylactic negative-pressure wound therapy for prevention of wound-related complications after abdomino-perineal resection: a systematic review

Abstract

Background

Methods

Results

Conclusion

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