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Published in: International Journal of Colorectal Disease 6/2020

01-06-2020 | Colonoscopy | Original Article

The impact of sedation on quality metrics of colonoscopy: a single-center experience of 48,838 procedures

Authors: Song Zhao, Xiao-lian Deng, Li Wang, Jing-wang Ye, Zheng-yong Liu, Bin Huang, Ying Kan, Bao-hua Liu, An-ping Zhang, Chun-xue Li, Fan Li, Wei-dong Tong

Published in: International Journal of Colorectal Disease | Issue 6/2020

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Abstract

Purpose

Investigation of the role of sedation during colonoscopy is meaningful as the advantages of colonoscopy performing with sedation are still controversial.

Methods

Medical records of patients who underwent colonoscopy in our institution were retrospectively analyzed. The sedation rate, adenoma detection rate (ADR), polyp detection rate (PDR), cecal intubation rate (CIR), iatrogenic colonic perforation rate (ICP) were calculated.

Results

A total of 48,838 colonoscopies (24,498 in males) dated from July 2007 to February 2017 were analyzed. The median age was 50 years (range 16–85 years). An overall sedation rate was 80.38%. The PDR was 26.77%, and was not statistically different between colonoscopy with or without sedation (26.67% vs 27.22, p = 0.474). ADR was 12.9% regardless of applying sedation or not (13.0% vs 12.44%, p = 0.337). The CIR was 87.42% in all examinations with an adjusted CIR of 90.34%, and was higher when performed with sedation than without sedation (88.92% vs 80.64%, p < 0.0001). Five cases (0.01%) of ICP were reported, all of which occurred in patients under sedation.

Conclusions

The use of sedation is associated with increased CIR, but ADR and PDR remain unchanged with or without sedation. However, perforation rate, albeit very low, is significantly higher in sedated patients.
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Metadata
Title
The impact of sedation on quality metrics of colonoscopy: a single-center experience of 48,838 procedures
Authors
Song Zhao
Xiao-lian Deng
Li Wang
Jing-wang Ye
Zheng-yong Liu
Bin Huang
Ying Kan
Bao-hua Liu
An-ping Zhang
Chun-xue Li
Fan Li
Wei-dong Tong
Publication date
01-06-2020
Publisher
Springer Berlin Heidelberg
Keyword
Colonoscopy
Published in
International Journal of Colorectal Disease / Issue 6/2020
Print ISSN: 0179-1958
Electronic ISSN: 1432-1262
DOI
https://doi.org/10.1007/s00384-020-03586-y

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ACKNOWLEDGMENTS

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