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International Journal of Colorectal Disease

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Open Access 01-11-2019 | Chronic Inflammatory Bowel Disease | Case Report

EBV-associated lymphoproliferative disorder involving the gastrointestinal tract which mimic IBD in immunocompetent patients: case reports and literature review

Authors: Yanhua Zhou, Yanlin Zhang, Haiying Zhao, Xuan Cui, Yongqiu Wei, Yongdong Wu, Shutian Zhang, Ye Zong

Published in: International Journal of Colorectal Disease | Issue 11/2019

Abstract

Introduction

Epstein-Barr virus (EBV)–associated lymphoproliferative diseases (LPD) with digestive tract involvement in immunocompetent patients is rather rare. Since the symptoms of EBV-associated LPD involving the gastrointestinal tract in immunocompetent patients are similar to those of inflammatory bowel disease (IBD), most patients are initially misdiagnosed.

Case presentation

In this paper, we present two cases of EBV-associated T cell LPD involving the colon in immunocompetent patients and review the relevant literature.

Conclusion

EBV serological testing may help in detecting this disease, and our findings suggest that histopathological evidence of EBV, such as the Epstein-Barr encoding region, is very important to establish the diagnosis.

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Title: EBV-associated lymphoproliferative disorder involving the gastrointestinal tract which mimic IBD in immunocompetent patients: case reports and literature review
Authors: Yanhua Zhou
Yanlin Zhang
Haiying Zhao
Xuan Cui
Yongqiu Wei
Yongdong Wu
Shutian Zhang
Ye Zong
Publication date: 01-11-2019
Publisher: Springer Berlin Heidelberg
Keywords: Chronic Inflammatory Bowel Disease
Epstein-Barr Virus
Colonoscopy
Published in: International Journal of Colorectal Disease / Issue 11/2019
Print ISSN: 0179-1958
Electronic ISSN: 1432-1262
DOI: https://doi.org/10.1007/s00384-019-03400-4

At a glance: The ONWARDS insulin icodec trials

Springer Medicine

EBV-associated lymphoproliferative disorder involving the gastrointestinal tract which mimic IBD in immunocompetent patients: case reports and literature review

Abstract

Introduction

Case presentation

Conclusion

At a glance: The ONWARDS insulin icodec trials

Springer Medicine

Abstract

Introduction

Case presentation

Conclusion

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