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International Journal of Colorectal Disease
Published in: International Journal of Colorectal Disease 6/2018

01-06-2018 | Original Article

Improved perioperative care is associated with improved long-term survival in colorectal cancer

Authors: Eligijus Poskus, Marius Kryzauskas, Tomas Poskus, Saulius Mikalauskas, Narimantas Evaldas Samalavicius, Oleg Aliosin, Sarunas Dailidenas, Algimantas Tamelis, Zilvinas Saladzinskas, Paulius Lizdenis, Audrone Jakaitiene, Giedre Smailyte, Kestutis Strupas

Published in: International Journal of Colorectal Disease | Issue 6/2018

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Abstract

Purpose

To compare perioperative colorectal cancer care and survival in patient cohorts operated in 2005 and in 2010 in Lithuania.

Methods

Comparative observational cohort study was performed. The study was conducted in the three Lithuanian cancer hospitals. Patients, who underwent curative surgery for colorectal cancer in 2005 and 2010, were included. Demographic characteristics, distribution of the tumors, preoperative diagnostics and staging, surgical treatment, the quality of pathological examination, morbidity, and mortality were analyzed. One- and 5-year overall survival data were compared between the groups.

Results

Colorectal cancer diagnostics and treatment improved from 2005 to 2010 significantly. The disease was identified as stage III–IV for 45 vs. 48% of the patients; however, computed tomography staging scan was performed only for 5.9 vs. 17.8% in 2005 and 2010, respectively. Laparoscopic operations were performed 1.5 vs. 10.5% and abdominoperineal resections—42.7 vs. 31.7% in 2005 and 2010, respectively. The number of harvested lymph nodes was mentioned in 55.8 vs. 97.7% of the cases, whereas more than 12 lymph nodes were examined in 18 vs. 66.6% of cases after histological examination. The overall 5-year survival was 52.1 vs. 63.1% (p < 0.0001), while the 5-year survival of the patients with stage IV of disease was 4.2 vs. 17.8% in 2005 and 2010, respectively.

Conclusion

Preoperative investigation, surgical treatment, pathological examination, and postoperative course are associated with improved overall survival in colorectal cancer patients, undergoing curative surgery in the resource-limited settings.
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Metadata
Title
Improved perioperative care is associated with improved long-term survival in colorectal cancer
Authors
Eligijus Poskus
Marius Kryzauskas
Tomas Poskus
Saulius Mikalauskas
Narimantas Evaldas Samalavicius
Oleg Aliosin
Sarunas Dailidenas
Algimantas Tamelis
Zilvinas Saladzinskas
Paulius Lizdenis
Audrone Jakaitiene
Giedre Smailyte
Kestutis Strupas
Publication date
01-06-2018
Publisher
Springer Berlin Heidelberg
Published in
International Journal of Colorectal Disease / Issue 6/2018
Print ISSN: 0179-1958
Electronic ISSN: 1432-1262
DOI
https://doi.org/10.1007/s00384-018-3021-y

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