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International Journal of Colorectal Disease
Published in: International Journal of Colorectal Disease 6/2018

01-06-2018 | Review

Chronic diarrhoea following surgery for colon cancer—frequency, causes and treatment options

Authors: Jonathan Yde, Helene M. Larsen, Søren Laurberg, Klaus Krogh, Hanne B. Moeller

Published in: International Journal of Colorectal Disease | Issue 6/2018

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Abstract

Purpose

The growing population of survivors after colon cancer warrants increased attention to the long-term outcome of surgical treatment. The change in bowel anatomy after resection disrupts normal gastrointestinal function and may cause symptoms. Thus, many patients surviving colon cancer have to cope with bowel dysfunction for the rest of their lives. We here aim to provide an overview of the literature on this topic.

Methods

We review long-term functional outcomes of surgical treatment for colon cancer, the underlying pathology, and treatment options.

Results

Common symptoms include constipation, urge for defecation and diarrhoea. Causes of diarrhoea after colon cancer surgery are sparsely studied, but they probably include bile acid malabsorption, small intestinal bacterial overgrowth and disruption of the ileal brake. Specific diagnosis should be made to allow individual treatment based on the underlying pathology. Studies on treatment of functional problems after surgery for colon cancer are extremely few, but some lessons can be drawn from the treatment of other patient groups having undergone colon surgery.

Conclusion

Diarrhoea is likely a common long-term complication after colon cancer surgery. Attention to this complication and a specific diagnosis will aid the targeted treatment of patients suffering from this complication.
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Metadata
Title
Chronic diarrhoea following surgery for colon cancer—frequency, causes and treatment options
Authors
Jonathan Yde
Helene M. Larsen
Søren Laurberg
Klaus Krogh
Hanne B. Moeller
Publication date
01-06-2018
Publisher
Springer Berlin Heidelberg
Published in
International Journal of Colorectal Disease / Issue 6/2018
Print ISSN: 0179-1958
Electronic ISSN: 1432-1262
DOI
https://doi.org/10.1007/s00384-018-2993-y

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